Successful Haploidentical Donor Hematopoietic Stem Cell Transplant and Restoration of STAT3 Function in an Adolescent with Autosomal Dominant Hyper-IgE Syndrome

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts

(2013) L. J. Berglund et al.   BLOOD

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function

(2013) Megan L. Ives et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells

(2013) Elissa K. Deenick et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clinical Features, STAT3 Gene Mutations and Th17 Cell Analysis in Nine Children with Hyper-IgE Syndrome in Mainland China

(2013) L.-Y. Zhang et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

DOCK8 deficiency

(2012) Helen C. Su et al.   Annals of the New York Academy of Sciences

Molecular mechanisms of the immunological abnormalities in hyper-IgE syndrome

(2012) Yoshiyuki Minegishi et al.   Annals of the New York Academy of Sciences

Effects of Conditioning Regimens and T Cell Depletion in Hematopoietic Cell Transplantation for Primary Immune Deficiency

(2012) Brandon M. Triplett et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

TH17 deficiency in human disease

(2012) Douglas R. McDonald   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An update on the hyper-IgE syndromes

(2012) Patrick FK Yong et al.   ARTHRITIS RESEARCH & THERAPY

A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory

(2011) Andrea M. Siegel et al.   IMMUNITY

Long-term immune deficiency after allogeneic stem cell transplantation: B-cell deficiency is associated with late infections

(2010) E. Corre et al.   HAEMATOLOGICA

Successful long-term immunologic reconstitution by allogeneic hematopoietic stem cell transplantation cures patients with autosomal dominant hyper-IgE syndrome

(2010) Evgenios Goussetis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

(2009) Yoshiyuki Minegishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Elevated Numbers of Immature/Transitional CD21− B Lymphocytes and Deficiency of Memory CD27+ B Cells Identify Patients with Active Chronic Graft-versus-Host Disease

(2008) Hildegard T. Greinix et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

The Hyper-IgE Syndromes

(2008) Alexandra F. Freeman et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3

(2008) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE