An update on the hyper-IgE syndromes

Hyper-IgE syndrome update

(2012) Kathryn J. Sowerwine et al.   Annals of the New York Academy of Sciences

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

(2012) Y. Harada et al.   BLOOD

Additional Diverse Findings Expand the Clinical Presentation of DOCK8 Deficiency

(2012) Ozden Sanal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

A Patient with Tyrosine Kinase 2 Deficiency without Hyper-IgE Syndrome

(2012) Sara S. Kilic et al.   JOURNAL OF PEDIATRICS

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

(2012) Haifa H Jabara et al.   NATURE IMMUNOLOGY

Successful bone marrow transplantation for DOCK8 deficient hyper IgE syndrome

(2012) Ayse Metin et al.   PEDIATRIC TRANSPLANTATION

Inactivation of IL11 Signaling Causes Craniosynostosis, Delayed Tooth Eruption, and Supernumerary Teeth

(2011) Pekka Nieminen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Pathobiology of Human Cervical High-Grade Lesions: Paracrine STAT3 Activation in Tumor-Instructed Myeloid Cells Drives Local MMP-9 Expression

(2011) N. Schroer et al.   CANCER RESEARCH

Frequent and Widespread Vascular Abnormalities in Human Signal Transducer and Activator of Transcription 3 Deficiency

(2011) Marie-Olivia Chandesris et al.   Circulation-Cardiovascular Genetics

Paucity of genotype–phenotype correlations in STAT3 mutation positive Hyper IgE Syndrome (HIES)

(2011) Jennifer Heimall et al.   CLINICAL IMMUNOLOGY

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

(2011) Teresa Lambe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory

(2011) Andrea M. Siegel et al.   IMMUNITY

Successful allogeneic hematopoietic stem cell transplantation for DOCK8 deficiency

(2011) Vincent Barlogis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Plasma metalloproteinase levels are dysregulated in signal transducer and activator of transcription 3 mutated hyper-IgE syndrome

(2011) Vibhav Sekhsaria et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Coronary Artery Abnormalities in Hyper-IgE Syndrome

(2011) Alexandra F. Freeman et al.   JOURNAL OF CLINICAL IMMUNOLOGY

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

(2011) Katrina L. Randall et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Curative treatment of autosomal-recessive hyper-IgE syndrome by hematopoietic cell transplantation

(2010) S A Gatz et al.   BONE MARROW TRANSPLANTATION

Anti-cytokine autoantibodies explain some chronic mucocutaneous candidiasis

(2010) Sarah K Browne et al.   IMMUNOLOGY AND CELL BIOLOGY

Diagnostic approach to the hyper-IgE syndromes: Immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis

(2010) Lena F. Schimke et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Successful long-term immunologic reconstitution by allogeneic hematopoietic stem cell transplantation cures patients with autosomal dominant hyper-IgE syndrome

(2010) Evgenios Goussetis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Invasive fungal disease in autosomal-dominant hyper-IgE syndrome

(2010) Donald C. Vinh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome

(2010) Cristina Woellner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Diffuse Large B Cell Lymphoma in Hyper-IgE Syndrome Due To STAT3 Mutation

(2010) Attila Kumánovics et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Successful Long-Term Correction of Autosomal Recessive Hyper-IgE Syndrome due to DOCK8 Deficiency by Hematopoietic Stem Cell Transplantation

(2010) T. C. Bittner et al.   KLINISCHE PADIATRIE

Elevated MMP-8 and Decreased Myeloperoxidase Concentrations Associate Significantly with the Risk for Peripheral Atherosclerosis Disease and Abdominal Aortic Aneurysm1

(2010) P. Pradhan-Palikhe et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Pneumocystis jirovecii pneumonia in a baby with hyper-IgE syndrome

(2009) Ben Zion Garty et al.   EUROPEAN JOURNAL OF PEDIATRICS

Pulmonary nontuberculous mycobacterial infections in hyper-IgE syndrome

(2009) Elizabeth Melia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

(2009) Karin R. Engelhardt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

(2009) Yoshiyuki Minegishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Matrix Metalloproteinase-8 Inactivates Macrophage Inflammatory Protein-1  To Reduce Acute Lung Inflammation and Injury in Mice

(2009) P. A. Quintero et al.   JOURNAL OF IMMUNOLOGY

An Unusual Giant Right Coronary Artery Aneurysm Resembles an Intracardiac Mass

(2008) Estibaliz Alomar-Melero et al.   ANESTHESIA AND ANALGESIA

Reduced memory B cells in patients with hyper IgE syndrome

(2008) C. Speckmann et al.   CLINICAL IMMUNOLOGY

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3

(2008) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel and recurrent STAT3 mutations in hyper-IgE syndrome patients from different ethnic groups

(2008) Hong Jiao et al.   MOLECULAR IMMUNOLOGY

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

(2008) Shean J Aujla et al.   NATURE MEDICINE

Fra-1 and Stat3 synergistically regulate activation of human MMP-9 gene

(2007) Yuhua Song et al.   MOLECULAR IMMUNOLOGY