HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression
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Title
HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression
Authors
Keywords
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Journal
BLOOD
Volume 124, Issue 8, Pages 1335-1343
Publisher
American Society of Hematology
Online
2014-06-06
DOI
10.1182/blood-2014-01-552281
References
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Related references
Note: Only part of the references are listed.- In Situ Proximity Ligation Assays Indicate That Hemochromatosis Proteins Hfe and Transferrin Receptor 2 (Tfr2) Do Not Interact
- (2013) Gautam Rishi et al. PLoS One
- Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2
- (2012) Paul J. Schmidt et al. AMERICAN JOURNAL OF HEMATOLOGY
- The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation
- (2012) Flavia D’Alessio et al. JOURNAL OF HEPATOLOGY
- Closing the Iron Gate
- (2012) Nancy C. Andrews NEW ENGLAND JOURNAL OF MEDICINE
- Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
- (2011) A. U. Steinbicker et al. BLOOD
- Hepcidin and iron regulation, 10 years later
- (2011) T. Ganz BLOOD
- Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
- (2011) A. U. Steinbicker et al. BLOOD
- Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension
- (2011) Koko Murakami et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Iron Regulation of Hepcidin Despite Attenuated Smad1,5,8 Signaling in Mice Without Transferrin Receptor 2 or Hfe
- (2011) Elena Corradini et al. GASTROENTEROLOGY
- Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin
- (2010) P. J. Schmidt et al. BLOOD
- Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice
- (2010) J. Gao et al. BLOOD
- Altered hepatic BMP signaling pathway in human HFE hemochromatosis
- (2010) Giuliano Bolondi et al. BLOOD CELLS MOLECULES AND DISEASES
- Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment
- (2010) Antonello Pietrangelo GASTROENTEROLOGY
- Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis
- (2010) John D. Ryan et al. HEPATOLOGY
- Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages
- (2010) Y. Xia et al. JOURNAL OF IMMUNOLOGY
- BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression
- (2009) L. Kautz et al. BLOOD
- Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression
- (2009) Junwei Gao et al. Cell Metabolism
- Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis
- (2009) Elena Corradini et al. GASTROENTEROLOGY
- Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload
- (2009) Daniel F. Wallace et al. HEPATOLOGY
- Lack of the bone morphogenetic protein BMP6 induces massive iron overload
- (2009) Delphine Meynard et al. NATURE GENETICS
- BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
- (2009) Billy Andriopoulos Jr et al. NATURE GENETICS
- Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
- (2008) Y. Xia et al. BLOOD
- The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression
- (2008) Paul J. Schmidt et al. Cell Metabolism
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