Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

(2010) B. J. Sasu et al.   BLOOD

In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2

(2010) K. Maes et al.   BLOOD

Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease

(2010) S.-N. J. Song et al.   BLOOD

Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitors

(2010) Omid F. Harandi et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice

(2010) Ivana De Domenico et al.   JOURNAL OF CLINICAL INVESTIGATION

STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo

(2009) Ryotaro Sakamori et al.   JOURNAL OF GASTROENTEROLOGY

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

(2008) Gregory D. Cuny et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

(2008) J. Truksa et al.   BLOOD

Fine Tuning of Hepcidin Expression by Positive and Negative Regulators

(2008) Martina U. Muckenthaler   Cell Metabolism

Involvement of Hepcidin in the Anemia of Multiple Myeloma

(2008) S. Sharma et al.   CLINICAL CANCER RESEARCH

New and old players in the hepcidin pathway

(2008) C. Camaschella et al.   HAEMATOLOGICA

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

(2008) Maria Vittoria Verga Falzacappa et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Evaluation and Long-Term Prognosis of New-Onset, Transient, and Persistent Anemia in Ambulatory Patients With Chronic Heart Failure

(2008) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

BMP type I receptor inhibition reduces heterotopic ossification

(2008) Paul B Yu et al.   NATURE MEDICINE

Gal4/UAS Transgenic Tools and Their Application to Zebrafish

(2008) Marnie E. Halpern et al.   Zebrafish