Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2

Iron Regulation of Hepcidin Despite Attenuated Smad1,5,8 Signaling in Mice Without Transferrin Receptor 2 or Hfe

(2011) Elena Corradini et al.   GASTROENTEROLOGY

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

(2011) Emilio Ramos et al.   HEPATOLOGY

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

(2010) P. J. Schmidt et al.   BLOOD

Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice

(2010) J. Gao et al.   BLOOD

Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis

(2010) D. H. Lee et al.   BLOOD

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-  and Tfr2-  isoforms in different tissues

(2010) A. Roetto et al.   BLOOD

BMP6 Treatment Compensates for the Molecular Defect and Ameliorates Hemochromatosis in Hfe Knockout Mice

(2010) Elena Corradini et al.   GASTROENTEROLOGY

Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8Å

(2010) Fan Yang et al.   JOURNAL OF STRUCTURAL BIOLOGY

Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression

(2009) Junwei Gao et al.   Cell Metabolism

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis

(2009) Elena Corradini et al.   GASTROENTEROLOGY

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

(2008) Abdul Waheed et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Neogenin Interacts with Hemojuvelin through Its Two Membrane-Proximal Fibronectin Type III Domains†

(2008) Fan Yang et al.   BIOCHEMISTRY

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism