The yin and yang of nitric oxide in cancer progression

Nitric oxide modifies chromatin to suppress ICAM-1 expression during colonic inflammation

(2012) Qingjie Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

nNOS downregulation attenuates neuronal apoptosis by inhibiting nNOS–GluR6 interaction and GluR6 nitrosylation in cerebral ischemic reperfusion

(2012) Jie-Hui Di et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide releasing prodrug inhibits androgen receptor and WNT-signaling in prostate cancer cells

(2012) Martin Laschak et al.   BMC CANCER

The prognostic importance of miR-21 in stage II colon cancer: a population-based study

(2012) S Kjaer-Frifeldt et al.   BRITISH JOURNAL OF CANCER

Targeting eNOS in Pancreatic Cancer

(2012) B. L. Lampson et al.   CANCER RESEARCH

Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways

(2012) Suboj Babykutty et al.   CLINICAL & EXPERIMENTAL METASTASIS

Dolastatin 15, a mollusk linear peptide, and Celecoxib, a selective cyclooxygenase-2 inhibitor, prevent preneoplastic colonic lesions and induce apoptosis through inhibition of the regulatory transcription factor NF-κB and an inflammatory protein, iNOS

(2012) Honit Piplani et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Emerging avenues linking inflammation and cancer

(2012) Joydeb Kumar Kundu et al.   FREE RADICAL BIOLOGY AND MEDICINE

NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression

(2012) Hirokazu Okayama et al.   INTERNATIONAL JOURNAL OF CANCER

S-Nitrosylation of EGFR and Src Activates an Oncogenic Signaling Network in Human Basal-Like Breast Cancer

(2012) C. H. Switzer et al.   MOLECULAR CANCER RESEARCH

Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells

(2012) Marlies Van de Wouwer et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Nitric Oxide Donor Exisulind Is an Effective Inhibitor of Murine Photocarcinogenesis†

(2012) Tripti Singh et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease

(2012) Jane J. Sohn et al.   PLoS One

In Vitro Epigenetic Reprogramming of Human Cardiac Mesenchymal Stromal Cells into Functionally Competent Cardiovascular Precursors

(2012) Matteo Vecellio et al.   PLoS One

S-nitrosylation in the regulation of gene transcription

(2011) Yonggang Sha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nitric oxide: role in tumour biology and iNOS/NO-based anticancer therapies

(2011) Simendra Singh et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Reduction of nitric oxide level enhances the radiosensitivity of hypoxic non-small cell lung cancer

(2011) Wael Saleem et al.   CANCER SCIENCE

Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2

(2011) Christine E. Eyler et al.   CELL

Mechanisms of nitric oxide-mediated inhibition of EMT in cancer

(2011) Stavroula Baritaki et al.   CELL CYCLE

Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer

(2011) Stefan Ambs et al.   CELL CYCLE

In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells

(2011) Marco Donia et al.   CELL CYCLE

iNOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes

(2011) Kewei Wang et al.   CELLULAR SIGNALLING

Mechanism of nitric oxide synthase regulation: Electron transfer and interdomain interactions

(2011) Changjian Feng   COORDINATION CHEMISTRY REVIEWS

Nitric Oxide and Cancer: The Emerging Role of S-Nitrosylation

(2011) E. Aranda et al.   CURRENT MOLECULAR MEDICINE

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Nitric Oxide Suppresses Tumor Cell Migration through N-Myc Downstream-regulated Gene-1 (NDRG1) Expression

(2011) Jason R. Hickok et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitric Oxide Radical-induced Radioadaptation and Radiosensitization Are G2/M Phase-dependent

(2011) Xiaoming SU et al.   JOURNAL OF RADIATION RESEARCH

Antitumor Actions of Ruthenium(III)-Based Nitric Oxide Scavengers and Nitric Oxide Synthase Inhibitors

(2011) F. W. Flitney et al.   MOLECULAR CANCER THERAPEUTICS

Silencing ofGSTP1, a Prostate Cancer Prognostic Gene, by the Estrogen Receptor-β and Endothelial Nitric Oxide Synthase Complex

(2011) A. Re et al.   MOLECULAR ENDOCRINOLOGY

Nitric Oxide Synthase Inhibition Enhances the Antitumor Effect of Radiation in the Treatment of Squamous Carcinoma Xenografts

(2011) Robert J. G. Cardnell et al.   PLoS One

DNA strand breaks and hypoxia response inhibition mediate the radiosensitisation effect of nitric oxide donors on prostate cancer under varying oxygen conditions

(2010) Grant D. Stewart et al.   BIOCHEMICAL PHARMACOLOGY

Nitration of the Tumor Suppressor Protein p53 at Tyrosine 327 Promotes p53 Oligomerization and Activation

(2010) Vasily A. Yakovlev et al.   BIOCHEMISTRY

Synthesis and biological evaluation of furoxan-based nitric oxide-releasing derivatives of glycyrrhetinic acid as anti-hepatocellular carcinoma agents

(2010) Yisheng Lai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nitric Oxide-Mediated Histone Hyperacetylation in Oral Cancer: Target for a Water-Soluble HAT Inhibitor, CTK7A

(2010) Mohammed Arif et al.   CHEMISTRY & BIOLOGY

Targeted Inhibition of Inducible Nitric Oxide Synthase Inhibits Growth of Human Melanoma In vivo and Synergizes with Chemotherapy

(2010) A. G. Sikora et al.   CLINICAL CANCER RESEARCH

Nitric Oxide Control of Proliferation in Nerve Cells and in Tumor Cells of Nervous Origin

(2010) Emiliano Pena-Altamira et al.   CURRENT PHARMACEUTICAL DESIGN

Nitric Oxide and Cancer Therapy: The Emperor has NO Clothes

(2010) Jason Hickok et al.   CURRENT PHARMACEUTICAL DESIGN

Cdk2 nitrosylation and loss of mitochondrial potential mediate NO-dependent biphasic effect on HL-60 cell cycle

(2010) Sachin Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitric Oxide: Perspectives and Emerging Studies of a Well Known Cytotoxin

(2010) William A. Paradise et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Risk factors of neurosensory deficits in lower third molar surgery: a literature review of prospective studies

(2010) Y.Y. Leung et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Evaluation of a multi-functional nanocarrier for targeted breast cancer iNOS gene therapy

(2010) Helen O. McCarthy et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biphasic Effects of Nitric Oxide Radicals on Radiation-Induced Lethality and Chromosome Aberrations in Human Lung Cancer Cells Carrying Different p53 Gene Status

(2010) Xiaoming Su et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Increased NOS2 predicts poor survival in estrogen receptor–negative breast cancer patients

(2010) Sharon A. Glynn et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy

(2010) Jonathan M. Weiss et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional regulation of inducible nitric oxide synthase gene therapy: targeting early stage and advanced prostate cancer

(2010) Jonathan A. Coulter et al.   JOURNAL OF GENE MEDICINE

JS-K has potent anti-angiogenic activityin vitroand inhibits tumour angiogenesis in a multiple myeloma modelin vivo

(2010) Tanyel Kiziltepe et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

GT-094, a NO-NSAID, Inhibits Colon Cancer Cell Growth by Activation of a Reactive Oxygen Species-MicroRNA-27a: ZBTB10-Specificity Protein Pathway

(2010) S. S. Pathi et al.   MOLECULAR CANCER RESEARCH

Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry

(2010) Benjamin Bonavida et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Modulators of arginine metabolism support cancer immunosurveillance

(2009) Giusy Capuano et al.   BMC IMMUNOLOGY

The novel NO-donating compound GIT-27NO inhibits in vivo growth of human prostate cancer cells and prevents murine immunoinflammatory hepatitis

(2009) Marco Donia et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nitric oxide suppresses transforming growth factor-β1-induced epithelial-to-mesenchymal transition and apoptosis in mouse hepatocytes

(2009) Xinchao Pan et al.   HEPATOLOGY

Molecular mechanisms of nitric oxide-dependent inhibition of TPA-induced matrix metalloproteinase-9 (MMP-9) in MCF-7 cells

(2009) Christine Jespersen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

NO sparks off chromatin: Tales of a multifaceted epigenetic regulator

(2009) Barbara Illi et al.   PHARMACOLOGY & THERAPEUTICS

The Impact of Intracellular Generation of Nitric Oxide on the Radiation Response of Human Tumor Cells

(2009) Simendra Singh et al.   RADIATION RESEARCH

Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling

(2009) J. B. Maxhimer et al.   Science Translational Medicine

Phase II Study of Nitric Oxide Donor for Men With Increasing Prostate-specific Antigen Level After Surgery or Radiotherapy for Prostate Cancer

(2009) D. Robert Siemens et al.   UROLOGY

Nitric Oxide Is a Key Component in Inflammation-Accelerated Tumorigenesis

(2008) S. P. Hussain et al.   CANCER RESEARCH

Hypoxic tumor cell radiosensitization through nitric oxide

(2008) Mark De Ridder et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Constitutive intracellular production of iNOS and NO in human melanoma: possible role in regulation of growth and resistance to apoptosis

(2008) Elizabeth A. Grimm et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Molecular mechanisms for discrete nitric oxide levels in cancer

(2008) Lisa A. Ridnour et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Regulation of apoptosis-related genes by nitric oxide in cancer

(2008) Samuel Y. Olson et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY