Microengineered tumor models: insights & opportunities from a physical sciences-oncology perspective
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Microengineered tumor models: insights & opportunities from a physical sciences-oncology perspective
Authors
Keywords
Cancer, Tumor microenvironment, Stroma, Transport, Tissue engineering, Biomaterials
Journal
BIOMEDICAL MICRODEVICES
Volume 15, Issue 4, Pages 583-593
Publisher
Springer Nature
Online
2013-04-04
DOI
10.1007/s10544-013-9763-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Multiscale Models of Breast Cancer Progression
- (2012) Anirikh Chakrabarti et al. ANNALS OF BIOMEDICAL ENGINEERING
- Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture
- (2012) Shawn P. Carey et al. BIOMATERIALS
- Spatial control of cell-mediated degradation to regulate vasculogenesis and angiogenesis in hyaluronan hydrogels
- (2012) Donny Hanjaya-Putra et al. BIOMATERIALS
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance
- (2012) Elizabeth S. Nakasone et al. CANCER CELL
- A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model
- (2012) B. J. Gill et al. CANCER RESEARCH
- Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targets
- (2012) Janice A. Nagy et al. CLINICAL & EXPERIMENTAL METASTASIS
- Individual versus collective fibroblast spreading and migration: Regulation by matrix composition in 3D culture
- (2012) Miguel Miron-Mendoza et al. EXPERIMENTAL EYE RESEARCH
- Anastomosis of endothelial sprouts forms new vessels in a tissue analogue of angiogenesis
- (2012) Jonathan W. Song et al. Integrative Biology
- Hedgehog signaling in myofibroblasts directly promotes prostate tumor cell growth
- (2012) Maribella Domenech et al. Integrative Biology
- Effects of Pharmacokinetic Processes and Varied Dosing Schedules on the Dynamics of Acquired Resistance to Erlotinib in EGFR-Mutant Lung Cancer
- (2012) Jasmine Foo et al. Journal of Thoracic Oncology
- Exploiting Evolution To Treat Drug Resistance: Combination Therapy and the Double Bind
- (2012) David Basanta et al. MOLECULAR PHARMACEUTICS
- Extracellular-matrix tethering regulates stem-cell fate
- (2012) Britta Trappmann et al. NATURE MATERIALS
- Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
- (2012) Jordan S. Miller et al. NATURE MATERIALS
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Controlled Breast Cancer Microarrays for the Deconvolution of Cellular Multilayering and Density Effects upon Drug Responses
- (2012) Maria Håkanson et al. PLoS One
- Independent regulation of tumor cell migration by matrix stiffness and confinement
- (2012) A. Pathak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Implanted adipose progenitor cells as physicochemical regulators of breast cancer
- (2012) E. M. Chandler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vitro microvessels for the study of angiogenesis and thrombosis
- (2012) Y. Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evolution of the cancer genome
- (2012) Ondrej Podlaha et al. TRENDS IN GENETICS
- Generating Nonlinear Concentration Gradients in Microfluidic Devices for Cell Studies
- (2011) Šeila Selimović et al. ANALYTICAL CHEMISTRY
- The Role of Body-on-a-Chip Devices in Drug and Toxicity Studies
- (2011) M.B. Esch et al. Annual Review of Biomedical Engineering
- Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform
- (2011) Badriprasad Ananthanarayanan et al. BIOMATERIALS
- Microfabricated scaffold-guided endothelial morphogenesis in three-dimensional culture
- (2011) Yuxin Liu et al. BIOMEDICAL MICRODEVICES
- Precisely targeted delivery of cells and biomolecules within microchannels using aqueous two-phase systems
- (2011) John P. Frampton et al. BIOMEDICAL MICRODEVICES
- Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments
- (2011) Ioannis K. Zervantonakis et al. Biomicrofluidics
- Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels
- (2011) Yanan Du et al. BIOTECHNOLOGY AND BIOENGINEERING
- Controlled activation of morphogenesis to generate a functional human microvasculature in a synthetic matrix
- (2011) D. Hanjaya-Putra et al. BLOOD
- Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game
- (2011) D Basanta et al. BRITISH JOURNAL OF CANCER
- Many Tumors in One: A Daunting Therapeutic Prospect
- (2011) Chibawanye I. Ene et al. CANCER CELL
- Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma
- (2011) Matija Snuderl et al. CANCER CELL
- Tumor Cell Invasion Is Promoted by Interstitial Flow-Induced Matrix Priming by Stromal Fibroblasts
- (2011) A. C. Shieh et al. CANCER RESEARCH
- Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber
- (2011) Ulrike Haessler et al. Integrative Biology
- Cellular modeling of cancer invasion: Integration of in silico and in vitro approaches
- (2011) Yoonseok Kam et al. JOURNAL OF CELLULAR PHYSIOLOGY
- In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients
- (2011) Yoojin Shin et al. LAB ON A CHIP
- Tumour evolution inferred by single-cell sequencing
- (2011) Nicholas Navin et al. NATURE
- Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
- (2011) Mina J Bissell et al. NATURE MEDICINE
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- Production of 2-hydroxyglutarate by isocitrate dehydrogenase 1-mutated gliomas: an evolutionary alternative to the Warburg shift?
- (2011) J. G. Scott et al. NEURO-ONCOLOGY
- Mechano-sensing and cell migration: a 3D model approach
- (2011) C Borau et al. PHYSICAL BIOLOGY
- Normalization of the Vasculature for Treatment of Cancer and Other Diseases
- (2011) Shom Goel et al. PHYSIOLOGICAL REVIEWS
- From Molecular Signal Activation to Locomotion: An Integrated, Multiscale Analysis of Cell Motility on Defined Matrices
- (2011) Amit Pathak et al. PLoS One
- Microfabricated Physical Spatial Gradients for Investigating Cell Migration and Invasion Dynamics
- (2011) Michael Mak et al. PLoS One
- Interstitial flow influences direction of tumor cell migration through competing mechanisms
- (2011) W. J. Polacheck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fluid forces control endothelial sprouting
- (2011) J. W. Song et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of Vascular Endothelial Growth Factor-Induced Pathfinding by Endothelial Sprouts in Biomaterials
- (2011) Amir Shamloo et al. TISSUE ENGINEERING PART A
- From 3D cell culture to organs-on-chips
- (2011) Dongeun Huh et al. TRENDS IN CELL BIOLOGY
- Microfluidic Platforms for Studies of Angiogenesis, Cell Migration, and Cell–Cell Interactions
- (2010) Seok Chung et al. ANNALS OF BIOMEDICAL ENGINEERING
- Expanding the Available Assays: Adapting and Validating In-Cell Westerns in Microfluidic Devices for Cell-Based Assays
- (2010) Amy L. Paguirigan et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Protein-engineered biomaterials: Nanoscale mimics of the extracellular matrix
- (2010) Nicole H. Romano et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- The role of cyclic AMP in normalizing the function of engineered human blood microvessels in microfluidic collagen gels
- (2010) Keith H.K. Wong et al. BIOMATERIALS
- Diffusion Anisotropy in Collagen Gels and Tumors: The Effect of Fiber Network Orientation
- (2010) Triantafyllos Stylianopoulos et al. BIOPHYSICAL JOURNAL
- Tumors on chips: oncology meets microfluidics
- (2010) Donald Wlodkowic et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Integration ofin silicoandin vitroplatforms for pharmacokinetic–pharmacodynamic modeling
- (2010) Jong Hwan Sung et al. Expert Opinion on Drug Metabolism & Toxicology
- Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo
- (2010) A. Beliveau et al. GENES & DEVELOPMENT
- Towards monitoring real-time cellular response using an integrated microfluidics-matrix assisted laser desorption ionisation/nanoelectrospray ionisation-ion mobility-mass spectrometry platform
- (2010) J.R. Enders et al. IET Systems Biology
- 3D microchannel co-culture: method and biological validation
- (2010) Maret Bauer et al. Integrative Biology
- Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis
- (2010) S. Raghavan et al. JOURNAL OF CELL SCIENCE
- A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip
- (2010) Jong Hwan Sung et al. LAB ON A CHIP
- Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients
- (2010) Amir Shamloo et al. LAB ON A CHIP
- Biomimetic materials in tissue engineering
- (2010) Jennifer Patterson et al. Materials Today
- A distinctive role for focal adhesion proteins in three-dimensional cell motility
- (2010) Stephanie I. Fraley et al. NATURE CELL BIOLOGY
- Oxygen-Controlled Three-Dimensional Cultures to Analyze Tumor Angiogenesis
- (2010) Scott S. Verbridge et al. TISSUE ENGINEERING PART A
- Tumor Engineering: The Other Face of Tissue Engineering
- (2010) Cyrus M. Ghajar et al. TISSUE ENGINEERING PART A
- Microfluidic Culture Models of Tumor Angiogenesis
- (2010) Abraham D. Stroock et al. TISSUE ENGINEERING PART A
- Engineering Tumors: A Tissue Engineering Perspective in Cancer Biology
- (2010) Emily Burdett et al. TISSUE ENGINEERING PART B-REVIEWS
- Microengineering Hydrogels for Stem Cell Bioengineering and Tissue Regeneration
- (2010) Ian Wheeldon et al. Journal of the Association for Laboratory Automation.
- Hydrogels as extracellular matrix mimics for 3D cell culture
- (2009) Mark W. Tibbitt et al. BIOTECHNOLOGY AND BIOENGINEERING
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Endothelial Cell Migration and Vascular Endothelial Growth Factor Expression Are the Result of Loss of Breast Tissue Polarity
- (2009) A. Chen et al. CANCER RESEARCH
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- Parylene peel-off arrays to probe the role of cell–cell interactions in tumour angiogenesis
- (2009) Christine P. Tan et al. Integrative Biology
- Integration column: microwell arrays for mammalian cell culture
- (2009) Mirren Charnley et al. Integrative Biology
- Biomimetic Macroporous Hydrogels: Protein Ligand Distribution and Cell Response to the Ligand Architecture in the Scaffold
- (2009) Irina N. Savina et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- A mechanosensitive transcriptional mechanism that controls angiogenesis
- (2009) Akiko Mammoto et al. NATURE
- A New Target for Tumor Therapy
- (2009) Rakesh K. Jain NEW ENGLAND JOURNAL OF MEDICINE
- Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement
- (2009) C. Fischbach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
- (2009) April M. Kloxin et al. SCIENCE
- Modular tissue engineering: engineering biological tissues from the bottom up
- (2009) Jason W. Nichol et al. Soft Matter
- Tissue stiffness, latent TGF-β1 Activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis
- (2009) Boris Hinz Current Rheumatology Reports
- Vascular permeability, vascular hyperpermeability and angiogenesis
- (2008) Janice A. Nagy et al. ANGIOGENESIS
- Imaging angiogenesis and the microenvironment
- (2008) DAI FUKUMURA et al. APMIS
- An adaptable hydrogel array format for 3-dimensional cell culture and analysis
- (2008) Leenaporn Jongpaiboonkit et al. BIOMATERIALS
- Microenvironment driven invasion: a multiscale multimodel investigation
- (2008) Alexander R. A. Anderson et al. JOURNAL OF MATHEMATICAL BIOLOGY
- Endothelial cell polarization and chemotaxis in a microfluidic device
- (2008) Amir Shamloo et al. LAB ON A CHIP
- Cell migration into scaffolds under co-culture conditions in a microfluidic platform
- (2008) Seok Chung et al. LAB ON A CHIP
- Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression
- (2008) Celeste M Nelson et al. Nature Protocols
- Invasion emerges from cancer cell adaptation to competitive microenvironments: Quantitative predictions from multiscale mathematical models
- (2008) Vito Quaranta et al. SEMINARS IN CANCER BIOLOGY
- Breast cancer by proxy: can the microenvironment be both the cause and consequence?
- (2008) Lone Rønnov-Jessen et al. TRENDS IN MOLECULAR MEDICINE
- Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices
- (2007) Walter Georgescu et al. LAB ON A CHIP
- Development of a Microscale Cell Culture Analog To Probe Naphthalene Toxicity
- (2004) Kwanchanok Viravaidya et al. BIOTECHNOLOGY PROGRESS
- The Design and Fabrication of Three-Chamber Microscale Cell Culture Analog Devices with Integrated Dissolved Oxygen Sensors
- (2004) Aaron Sin et al. BIOTECHNOLOGY PROGRESS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now