Integration ofin silicoandin vitroplatforms for pharmacokinetic–pharmacodynamic modeling

A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip

(2010) Jong Hwan Sung et al.   LAB ON A CHIP

Microchannel Technologies for Artificial Lungs: (1) Theory

(2009) J K. Lee et al.   ASAIO JOURNAL

Microchannel Technologies for Artificial Lungs: (3) Open Rectangular Channels

(2009) J-K Lee et al.   ASAIO JOURNAL

Microchannel Technologies for Artificial Lungs: (2) Screen-filled Wide Rectangular Channels

(2009) M C. Kung et al.   ASAIO JOURNAL

Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

(2009) P. Chao et al.   BIOCHEMICAL PHARMACOLOGY

Prevention of air bubble formation in a microfluidic perfusion cell culture system using a microscale bubble trap

(2009) Jong Hwan Sung et al.   BIOMEDICAL MICRODEVICES

In vitro microscale systems for systematic drug toxicity study

(2009) Jong Hwan Sung et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices

(2009) Jong Hwan Sung et al.   BIOTECHNOLOGY AND BIOENGINEERING

Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity

(2009) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Relationship Between the Pharmacokinetics of Levosimendan and Its Effects on Cardiovascular System

(2009) Charalambos Antoniades et al.   CURRENT DRUG METABOLISM

Scaling Pharmacodynamics from In Vitro and Preclinical Animal Studies to Humans

(2009) Donald E. Mager et al.   Drug Metabolism and Pharmacokinetics

Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments

(2009) Chi Zhang et al.   LAB ON A CHIP

A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

(2009) Jong Hwan Sung et al.   LAB ON A CHIP

A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells

(2009) Kyung-Jin Jang et al.   LAB ON A CHIP

Perfused multiwell plate for 3D liver tissue engineering

(2009) Karel Domansky et al.   LAB ON A CHIP

The Wearable Artificial Kidney, Why and How: From Holy Grail to Reality

(2009) Victor Gura et al.   SEMINARS IN DIALYSIS

Towards microfabricated biohybrid artificial lung modules for chronic respiratory support

(2008) Kristie A. Burgess et al.   BIOMEDICAL MICRODEVICES

A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers

(2008) Daniel A. Tatosian et al.   BIOTECHNOLOGY AND BIOENGINEERING

Recent Advances in High Throughput Screening for ADME Properties

(2008) Timothy Carlson et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

PK/PD modelling and simulations: utility in drug development

(2008) Iris Rajman   DRUG DISCOVERY TODAY

Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability☆

(2008) Gretchen J. Mahler et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A Combined Pharmacokinetic–Pharmacodynamic (PK–PD) Model for Tumor Growth in the Rat with UFT Administration

(2008) Jong Hwan Sung et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Bayesian Calibration of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model of Carbaryl Cholinesterase Inhibition

(2008) Andy Nong et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Automated cell culture in high density tubeless microfluidic device arrays

(2008) Ivar Meyvantsson et al.   LAB ON A CHIP

Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device

(2008) Bo Ma et al.   LAB ON A CHIP

Development of a physiologically based pharmacokinetic and pharmacodynamic model to determine dosimetry and cholinesterase inhibition for a binary mixture of chlorpyrifos and diazinon in the rat

(2008) C. Timchalk et al.   NEUROTOXICOLOGY

Connected Culture of Murine Hepatocytes and Human Umbilical Vein Endothelial Cells in a Multicompartmental Bioreactor

(2008) Federico Vozzi et al.   TISSUE ENGINEERING PART A

Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research

(2008) M DANHOF et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mechanisms and Consequences of Neutrophil Interaction with the Endothelium

(2007) Alexander Zarbock et al.   AMERICAN JOURNAL OF PATHOLOGY

Microfluidics for drug discovery and development: From target selection to product lifecycle management

(2007) L KANG   DRUG DISCOVERY TODAY

Analysis of pressure-driven air bubble elimination in a microfluidic device

(2007) Joo H. Kang et al.   LAB ON A CHIP

Biomolecular gradients in cell culture systems

(2007) Thomas M. Keenan et al.   LAB ON A CHIP

Development of a Microscale Cell Culture Analog To Probe Naphthalene Toxicity

(2004) Kwanchanok Viravaidya et al.   BIOTECHNOLOGY PROGRESS

Incorporation of 3T3-L1 Cells To Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies

(2004) Kwanchanok Viravaidya et al.   BIOTECHNOLOGY PROGRESS

The Design and Fabrication of Three-Chamber Microscale Cell Culture Analog Devices with Integrated Dissolved Oxygen Sensors

(2004) Aaron Sin et al.   BIOTECHNOLOGY PROGRESS