Multiscale Models of Breast Cancer Progression

Reverse engineering biomolecular systems using -omic data: challenges, progress and opportunities

(2012) C. F. Quo et al.   BRIEFINGS IN BIOINFORMATICS

Identification of aberrant pathways and network activities from high-throughput data

(2012) J. Wang et al.   BRIEFINGS IN BIOINFORMATICS

The tumor microenvironment is a dominant force in multidrug resistance

(2012) Ana Luísa Correia et al.   DRUG RESISTANCE UPDATES

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

A hybrid continuum-discrete modelling approach to predict and control angiogenesis: analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology

(2012) A. Das et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sprouting Angiogenesis under a Chemical Gradient Regulated by Interactions with an Endothelial Monolayer in a Microfluidic Platform

(2011) Gi Seok Jeong et al.   ANALYTICAL CHEMISTRY

Biomechanical Forces Shape the Tumor Microenvironment

(2011) Adrian C. Shieh   ANNALS OF BIOMEDICAL ENGINEERING

Multiscale Cancer Modeling

(2011) Thomas S. Deisboeck et al.   Annual Review of Biomedical Engineering

Microfluidics-based devices: New tools for studying cancer and cancer stem cell migration

(2011) Yu Huang et al.   Biomicrofluidics

Combining literature text mining with microarray data: advances for system biology modeling

(2011) A. Faro et al.   BRIEFINGS IN BIOINFORMATICS

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks

(2011) Suling Liu et al.   CANCER RESEARCH

Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cells

(2011) Ryan Tasseff et al.   Integrative Biology

Breast cancer — one term, many entities?

(2011) Nicholas R. Bertos et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeted therapies for breast cancer

(2011) Michaela J. Higgins et al.   JOURNAL OF CLINICAL INVESTIGATION

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

(2011) Hasan Korkaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Congestive Heart Failure Risk in Patients With Breast Cancer Treated With Bevacizumab

(2011) Toni K. Choueiri et al.   JOURNAL OF CLINICAL ONCOLOGY

In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients

(2011) Yoojin Shin et al.   LAB ON A CHIP

State of the art in computational modelling of cancer

(2011) K. A. Rejniak et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Genome-wide transcription factor binding: beyond direct target regulation

(2011) Kyle L. MacQuarrie et al.   TRENDS IN GENETICS

Ensembles of signal transduction models using Pareto Optimal Ensemble Techniques (POETs)

(2010) Sang Ok Song et al.   Biotechnology Journal

Discovering molecular targets in cancer with multiscale modeling

(2010) Zhihui Wang et al.   DRUG DEVELOPMENT RESEARCH

Phase III Study of Bevacizumab Plus Docetaxel Compared With Placebo Plus Docetaxel for the First-Line Treatment of Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer

(2010) David W. Miles et al.   JOURNAL OF CLINICAL ONCOLOGY

Identifying therapeutic targets in a combined EGFR-TGF R signalling cascade using a multiscale agent-based cancer model

(2010) Z. Wang et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

Ensembles of uncertain mathematical models can identify network response to therapeutic interventions

(2010) Deyan Luan et al.   Molecular BioSystems

Benchmarks for identification of ordinary differential equations from time series data

(2009) Peter Gennemark et al.   BIOINFORMATICS

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Prediction of Drug Response in Breast Cancer Using Integrative Experimental/Computational Modeling

(2009) H. B. Frieboes et al.   CANCER RESEARCH

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

"Antimyeloangiogenic" Therapy for Cancer by Inhibiting PlGF

(2009) S. Loges et al.   CLINICAL CANCER RESEARCH

Multiscale models of angiogenesis

(2009) A.A. Qutub et al.   IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE

Evolution of cell motility in an individual-based model of tumour growth

(2009) P. Gerlee et al.   JOURNAL OF THEORETICAL BIOLOGY

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

(2009) C. Fischbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-organization of engineered epithelial tubules by differential cellular motility

(2009) H. Mori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiscale Modeling of Form and Function

(2009) A. J. Engler et al.   SCIENCE

Modelling evolutionary cell behaviour using neural networks: Application to tumour growth

(2008) P. Gerlee et al.   BIOSYSTEMS

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

Quantitative modeling perspectives on the ErbB system of cell regulatory processes

(2008) Matthew J. Lazzara et al.   EXPERIMENTAL CELL RESEARCH

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

(2008) Mark A. LaBarge et al.   Integrative Biology

An improved algorithm for in situ adaptive tabulation

(2008) Liuyan Lu et al.   JOURNAL OF COMPUTATIONAL PHYSICS

Angiogenesis and vascular remodelling in normal and cancerous tissues

(2008) Markus R. Owen et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Microenvironment driven invasion: a multiscale multimodel investigation

(2008) Alexander R. A. Anderson et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Multiscale modelling and nonlinear simulation of vascular tumour growth

(2008) Paul Macklin et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Simulating brain tumor heterogeneity with a multiscale agent-based model: Linking molecular signatures, phenotypes and expansion rate

(2008) Le Zhang et al.   MATHEMATICAL AND COMPUTER MODELLING

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

(2008) Celeste M Nelson et al.   Nature Protocols

Modelling and analysis of gene regulatory networks

(2008) Guy Karlebach et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Co-evolution of tumor cells and their microenvironment

(2008) Kornelia Polyak et al.   TRENDS IN GENETICS

Characterizing emergent properties of immunological systems with multi-cellular rule-based computational modeling

(2008) Arvind K. Chavali et al.   TRENDS IN IMMUNOLOGY