Metabolic syndrome meets osteoarthritis

Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA)

(2016) Kazuo Yudoh et al.   Aging-US

Osteoarthritis and the metabolic syndrome: more evidence that the etiology of OA is different in men and women

(2012) K.M. Huffman et al.   OSTEOARTHRITIS AND CARTILAGE

Sex dimorphism in the association of cardiometabolic characteristics and osteophytes-defined radiographic knee osteoarthritis among obese and non-obese adults: NHANES III

(2012) C.A. Karvonen-Gutierrez et al.   OSTEOARTHRITIS AND CARTILAGE

The presence of total knee or hip replacements due to osteoarthritis enhances the positive association between hand osteoarthritis and atherosclerosis in women: the AGES-Reykjavik study

(2011) H. Jonsson et al.   ANNALS OF THE RHEUMATIC DISEASES

Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype

(2011) F. Berenbaum   ANNALS OF THE RHEUMATIC DISEASES

Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study

(2011) S Clockaerts et al.   ANNALS OF THE RHEUMATIC DISEASES

Correlation of Plasma and Synovial Fluid Adiponectin with Knee Osteoarthritis Severity

(2011) Sittisak Honsawek et al.   ARCHIVES OF MEDICAL RESEARCH

Regulation of subchondral bone osteoblast metabolism by cyclic compression

(2011) Christelle Sanchez et al.   ARTHRITIS AND RHEUMATISM

Inflammatory effect of advanced glycation end products on human meniscal cells from osteoarthritic knees

(2011) Hideki Hiraiwa et al.   INFLAMMATION RESEARCH

A Benzamide-Linked Small Molecule HS-Cf Inhibits TNF-α-Induced Interferon Regulatory Factor-1 in Porcine Chondrocytes: A Potential Disease-Modifying Drug for Osteoarthritis Therapeutics

(2011) Feng-Cheng Liu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Association of Knee Osteoarthritis with the Accumulation of Metabolic Risk Factors Such as Overweight, Hypertension, Dyslipidemia, and Impaired Glucose Tolerance in Japanese Men and Women: The ROAD Study

(2011) NORIKO YOSHIMURA et al.   JOURNAL OF RHEUMATOLOGY

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

What's new in our understanding of the role of adipokines in rheumatic diseases?

(2011) Rodolfo Gómez et al.   Nature Reviews Rheumatology

A rat model of early stage osteonecrosis induced by glucocorticoids

(2011) Mohammad Kerachian et al.   Journal of Orthopaedic Surgery and Research

Association of 25-hydroxyvitamin D with prevalent osteoarthritis of the hip in elderly men: The osteoporotic fractures in men study

(2010) R. K. Chaganti et al.   ARTHRITIS AND RHEUMATISM

ORIGINAL ARTICLE: The association of serum vitamin D level with presence of metabolic syndrome and hypertension in middle-aged Korean subjects

(2010) Mee K. Kim et al.   CLINICAL ENDOCRINOLOGY

The evolving role of obesity in knee osteoarthritis

(2010) MaryFran R Sowers et al.   CURRENT OPINION IN RHEUMATOLOGY

Vitamin D and Cardiovascular Disease: A Novel Agent for Reducing Cardiovascular Risk?

(2010) Panagiotis Anagnostis et al.   Current Vascular Pharmacology

Statins: A potential role in the management of osteoarthritis?

(2010) Joseph F. Baker et al.   JOINT BONE SPINE

Implications of increased bone density in osteoarthritis

(2010) David Hamerman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoarthritis: Another Component of Metabolic Syndrome?

(2010) Manuel T. Velasquez et al.   Metabolic Syndrome and Related Disorders

Peroxisome proliferator-activated receptor gamma in osteoarthritis

(2010) Hassan Fahmi et al.   Modern Rheumatology

Obesity punches above its weight in osteoarthritis

(2010) Richard M. Aspden   Nature Reviews Rheumatology

Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults

(2010) O. Stannus et al.   OSTEOARTHRITIS AND CARTILAGE

Lipid metabolism and osteoarthritis: Lessons from atherosclerosis

(2010) Vasiliki Gkretsi et al.   PROGRESS IN LIPID RESEARCH

Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor- B in human osteoarthritis chondrocytes

(2010) Z. Rasheed et al.   RHEUMATOLOGY

Synovial fluid level of adiponectin correlated with levels of aggrecan degradation markers in osteoarthritis

(2010) Dongsheng Hao et al.   RHEUMATOLOGY INTERNATIONAL

Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression

(2010) Marie-Solange Mutabaruka et al.   ARTHRITIS RESEARCH & THERAPY

Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis

(2009) M Filkova et al.   ANNALS OF THE RHEUMATIC DISEASES

Vascular cell adhesion molecule 1 as a predictor of severe osteoarthritis of the hip and knee joints

(2009) Georg Schett et al.   ARTHRITIS AND RHEUMATISM

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

(2009) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Knee osteoarthritis in obese women with cardiometabolic clustering

(2009) Maryfran Sowers et al.   ARTHRITIS AND RHEUMATISM

A comprehensive definition for metabolic syndrome

(2009) P. L. Huang   Disease Models & Mechanisms

Vitamin D Status, Bone Mineral Density, and the Development of Radiographic Osteoarthritis of the Knee

(2009) Arjan P. Bergink et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Adipokines in the skeleton: influence on cartilage function and joint degenerative diseases

(2009) Rodolfo Gomez et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Plasma Adiponectin in Patients with Active, Early, and Chronic Rheumatoid Arthritis Who Are Steroid- and Disease-Modifying Antirheumatic Drug-Naive Compared with Patients with Osteoarthritis and Controls

(2009) T. B. LAURBERG et al.   JOURNAL OF RHEUMATOLOGY

Levels of vitamin D and cardiometabolic disorders: Systematic review and meta-analysis

(2009) Johanna Parker et al.   MATURITAS

Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage

(2009) L.A. Collins-Racie et al.   OSTEOARTHRITIS AND CARTILAGE

Increased Prevalence of Metabolic Syndrome in Individuals with Osteoarthritis: An Analysis of NHANES III Data

(2009) Rajitkanok Amy Puenpatom et al.   POSTGRADUATE MEDICINE

Protective effects of total fraction of avocado/soybean unsaponifiables on the structural changes in experimental dog osteoarthritis: inhibition of nitric oxide synthase and matrix metalloproteinase-13

(2009) Christelle Boileau et al.   ARTHRITIS RESEARCH & THERAPY

Hand osteoarthritis in older women is associated with carotid and coronary atherosclerosis: the AGES Reykjavik study

(2008) H Jonsson et al.   ANNALS OF THE RHEUMATIC DISEASES

Generalized vibratory deficits in osteoarthritis of the hip

(2008) Najia Shakoor et al.   ARTHRITIS AND RHEUMATISM

Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice

(2008) Qiuqian Wu et al.   ARTHRITIS AND RHEUMATISM

Leptin: Linking obesity, the metabolic syndrome, and cardiovascular disease

(2008) Sanjeev B. Patel et al.   CURRENT HYPERTENSION REPORTS

Fat overload aggravates oxidative stress in patients with the metabolic syndrome

(2008) F. Cardona et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Osteoarthritis and obesity: Experimental models

(2008) Odile Gabay et al.   JOINT BONE SPINE

TG-interacting factor is required for the differentiation of preadipocytes

(2008) Takahiro Horie et al.   JOURNAL OF LIPID RESEARCH

Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome

(2008) Valéria A. Gomes et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

A new player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes

(2008) R. Lago et al.   OSTEOARTHRITIS AND CARTILAGE

C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study

(2008) G. Engström et al.   OSTEOARTHRITIS AND CARTILAGE

Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks

(2008) Dimitrios Iliopoulos et al.   PLoS One

Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes

(2008) S.-S. Nah et al.   RHEUMATOLOGY

Adiponectin mitigates the severity of arthritis in mice with collagen‐induced arthritis

(2008) S‐W. Lee et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Dynamic compression counteracts IL-1beta induced iNOS and COX-2 expression in chondrocyte / agarose constructs

(2008) Tina T Chowdhury et al.   ARTHRITIS RESEARCH & THERAPY

Stress-induced signaling pathways in hyalin chondrocytes: inhibition by Avocado–Soybean Unsaponifiables (ASU)

(2007) O. Gabay et al.   OSTEOARTHRITIS AND CARTILAGE