The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein

Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration

(2015) Valentina Castillo et al.   PLoS One

ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

(2014) Prasanna Satpute-Krishnan et al.   CELL

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases

(2014) Claudio Hetz et al.   NATURE REVIEWS NEUROSCIENCE

The GPI-anchoring of PrP

(2014) Berta Puig et al.   Prion

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis

(2012) D Rojas-Rivera et al.   CELL DEATH AND DIFFERENTIATION

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α

(2012) Diego A Rodriguez et al.   EMBO JOURNAL

Protein disulfide isomerases in neurodegeneration: From disease mechanisms to biomedical applications

(2012) Catherine I. Andreu et al.   FEBS LETTERS

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

(2012) Julie A. Moreno et al.   NATURE

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Altered Prion Protein Expression Pattern in CSF as a Biomarker for Creutzfeldt-Jakob Disease

(2012) Mauricio Torres et al.   PLoS One

Protein Disulfide Isomerase Regulates Endoplasmic Reticulum Stress and the Apoptotic Process during Prion Infection and PrP Mutant-Induced Cytotoxicity

(2012) Shao-Bin Wang et al.   PLoS One

Endoplasmic reticulum stress and prion diseases

(2012) Kun Xu et al.   REVIEWS IN THE NEUROSCIENCES

Proteasomal Dysfunction and Endoplasmic Reticulum Stress Enhance Trafficking of Prion Protein Aggregates through the Secretory Pathway and Increase Accumulation of Pathologic Prion Protein

(2011) Max Nunziante et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial CJD Associated PrP Mutants within Transmembrane Region Induced Ctm-PrP Retention in ER and Triggered Apoptosis by ER Stress in SH-SY5Y Cells

(2011) Xin Wang et al.   PLoS One

Expression of Mutant or Cytosolic PrP in Transgenic Mice and Cells Is Not Associated with Endoplasmic Reticulum Stress or Proteasome Dysfunction

(2011) Elena Quaglio et al.   PLoS One

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Disulfide bonds in ER protein folding and homeostasis

(2010) Matthias J Feige et al.   CURRENT OPINION IN CELL BIOLOGY

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase

(2010) Helen Coe et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

(2010) Benjamin G Hoffstrom et al.   Nature Chemical Biology

Axonal prion protein is required for peripheral myelin maintenance

(2010) Juliane Bremer et al.   NATURE NEUROSCIENCE

Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress

(2010) Mauricio Torres et al.   PLoS One

Prion hypothesis: the end of the controversy?

(2010) Claudio Soto   TRENDS IN BIOCHEMICAL SCIENCES

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

(2009) C. Hetz et al.   GENES & DEVELOPMENT

ERp57 Modulates STAT3 Signaling from the Lumen of the Endoplasmic Reticulum

(2009) Helen Coe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins

(2009) C. E. Jessop et al.   JOURNAL OF CELL SCIENCE

BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α

(2009) Fernanda Lisbona et al.   MOLECULAR CELL

Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones

(2009) Joel C. Watts et al.   PLoS Pathogens

Reduced Translocation of Nascent Prion Protein During ER Stress Contributes to Neurodegeneration

(2008) Neena S. Rane et al.   DEVELOPMENTAL CELL

Substrate Specificity of the Oxidoreductase ERp57 Is Determined Primarily by Its Interaction with Calnexin and Calreticulin

(2008) Catherine E. Jessop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retrotranslocation of Prion Proteins from the Endoplasmic Reticulum by Preventing GPI Signal Transamidation

(2008) Aarthi Ashok et al.   MOLECULAR BIOLOGY OF THE CELL

Mutant Prion Protein Expression Causes Motor and Memory Deficits and Abnormal Sleep Patterns in a Transgenic Mouse Model

(2008) Sara Dossena et al.   NEURON

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis

(2008) C. Hetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading

(2008) D. R. Peaper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA