Glycogen Synthase Kinase-3 (GSK3) Inhibition Induces Prosurvival Autophagic Signals in Human Pancreatic Cancer Cells
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Title
Glycogen Synthase Kinase-3 (GSK3) Inhibition Induces Prosurvival Autophagic Signals in Human Pancreatic Cancer Cells
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 9, Pages 5592-5605
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-01-06
DOI
10.1074/jbc.m114.616714
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Note: Only part of the references are listed.- Autophagy promotesBrafV600E-driven lung tumorigenesis by preserving mitochondrial metabolism
- (2014) Anne M Strohecker et al. Autophagy
- Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs
- (2014) Daisuke Hashimoto et al. EUROPEAN JOURNAL OF CANCER
- Quantitative Glycoproteomics Analysis Reveals Changes in N-Glycosylation Level Associated with Pancreatic Ductal Adenocarcinoma
- (2014) Sheng Pan et al. JOURNAL OF PROTEOME RESEARCH
- The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris
- (2014) J. A. Martina et al. Science Signaling
- Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells
- (2014) J-S Zhang et al. Cell Death & Disease
- Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
- (2013) Jing Zhou et al. CELL RESEARCH
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
- (2013) Constance S. Petit et al. JOURNAL OF CELL BIOLOGY
- Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes
- (2013) Jose A. Martina et al. JOURNAL OF CELL BIOLOGY
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- Emerging regulation and functions of autophagy
- (2013) Patricia Boya et al. NATURE CELL BIOLOGY
- The autophagosome: origins unknown, biogenesis complex
- (2013) Christopher A. Lamb et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Signals from the lysosome: a control centre for cellular clearance and energy metabolism
- (2013) Carmine Settembre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Aberrant Glycogen Synthase Kinase 3β Is Involved in Pancreatic Cancer Cell Invasion and Resistance to Therapy
- (2013) Ayako Kitano et al. PLoS One
- Interplay between autophagy and apoptosis in pancreatic tumors in response to gemcitabine
- (2013) Daniela Laura Papademetrio et al. Targeted Oncology
- Autophagy: shaping the tumor microenvironment and therapeutic response
- (2013) Hannelore Maes et al. TRENDS IN MOLECULAR MEDICINE
- GSK-3α Promotes Oncogenic KRAS Function in Pancreatic Cancer via TAK1–TAB Stabilization and Regulation of Noncanonical NF-κB
- (2013) Deepali Bang et al. Cancer Discovery
- The Autophagy Inhibitor Verteporfin Moderately Enhances the Antitumor Activity of Gemcitabine in a Pancreatic Ductal Adenocarcinoma Model
- (2013) Elizabeth Donohue et al. Journal of Cancer
- An Emerging Strategy for Cancer Treatment Targeting Aberrant Glycogen Synthase Kinase 3β
- (2012) Katsuyoshi Miyashita et al. Anti-Cancer Agents in Medicinal Chemistry
- MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
- (2012) Jose A. Martina et al. Autophagy
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- Autophagy and cancer - issues we need to digest
- (2012) E. Y. Liu et al. JOURNAL OF CELL SCIENCE
- Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid- Precursor Protein
- (2012) C. Parr et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival
- (2012) Alejo Efeyan et al. NATURE
- GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
- (2012) S.-Y. Lin et al. SCIENCE
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- A critical role for autophagy in pancreatic cancer
- (2011) Shenghong Yang et al. Autophagy
- Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms
- (2011) B. Marchand et al. CARCINOGENESIS
- Pancreatic cancers require autophagy for tumor growth
- (2011) S. Yang et al. GENES & DEVELOPMENT
- Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
- (2011) J. Y. Guo et al. GENES & DEVELOPMENT
- Biology and Clinical Relevance of the Micropthalmia Family of Transcription Factors in Human Cancer
- (2011) Rizwan Haq et al. JOURNAL OF CLINICAL ONCOLOGY
- A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells
- (2011) François-Michel Boisvert et al. MOLECULAR & CELLULAR PROTEOMICS
- The role of antimalarial agents in the treatment of SLE and lupus nephritis
- (2011) Senq-J Lee et al. Nature Reviews Nephrology
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells
- (2011) A. N. Kettenbach et al. Science Signaling
- GSK-3β promotes cell survival by modulating Bif-1-dependent autophagy and cell death
- (2010) Jun Yang et al. JOURNAL OF CELL SCIENCE
- Gemcitabine Induces the VMP1 -Mediated Autophagy Pathway to Promote Apoptotic Death in Human Pancreatic Cancer Cells
- (2010) Romina Pardo et al. PANCREATOLOGY
- Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization
- (2010) Seung-Beom Hong et al. PLoS One
- Autophagy and Metabolism
- (2010) J. D. Rabinowitz et al. SCIENCE
- Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis
- (2010) J. V. Olsen et al. Science Signaling
- Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy
- (2009) Shadi Mamaghani et al. BMC CANCER
- CDC25B Mediates Rapamycin-Induced Oncogenic Responses in Cancer Cells
- (2009) R.-q. Chen et al. CANCER RESEARCH
- Maintenance of Constitutive I B Kinase Activity by Glycogen Synthase Kinase-3 / in Pancreatic Cancer
- (2008) W. Wilson et al. CANCER RESEARCH
- Preclinical efficacy on GSK-3 inhibitors: Towards a future generation of powerful drugs
- (2008) Ana Martinez MEDICINAL RESEARCH REVIEWS
- A quantitative atlas of mitotic phosphorylation
- (2008) N. Dephoure et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
- (2008) S. Jones et al. SCIENCE
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