A Heterodimer of a VHH (Variable Domains of Camelid Heavy Chain-only) Antibody That Inhibits Anthrax Toxin Cell Binding Linked to a VHH Antibody That Blocks Oligomer Formation Is Highly Protective in an Anthrax Spore Challenge Model

Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

(2014) Abhineet S. Sheoran et al.   INFECTION AND IMMUNITY

A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice

(2014) Zhiyong Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Prolonged Prophylactic Protection from Botulism with a Single Adenovirus Treatment Promoting Serum Expression of a VHH-Based Antitoxin Protein

(2014) Jean Mukherjee et al.   PLoS One

Anthrax lethal and edema toxins in anthrax pathogenesis

(2014) Shihui Liu et al.   TRENDS IN MICROBIOLOGY

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

Anthrax vaccines: present status and future prospects

(2013) Manpreet Kaur et al.   Expert Review of Vaccines

A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2

(2013) Jacqueline M. Tremblay et al.   INFECTION AND IMMUNITY

Stepwise Engineering of Heterodimeric Single Domain Camelid VHH Antibodies That Passively Protect Mice from Ricin Toxin

(2013) David J. Vance et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vivo Neutralization of Botulinum Neurotoxins Serotype E with Heavy-chain Camelid Antibodies (VHH)

(2013) Hamid Bakherad et al.   MOLECULAR BIOTECHNOLOGY

Nanobodies and their potential applications

(2013) Gholamreza Hassanzadeh-Ghassabeh et al.   Nanomedicine

In Vivo Neutralization of α-Cobratoxin with High-Affinity Llama Single-Domain Antibodies (VHHs) and a VHH-Fc Antibody

(2013) Gabrielle Richard et al.   PLoS One

A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism

(2012) M O Alberti et al.   GENE THERAPY

A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model

(2012) Jean Mukherjee et al.   PLoS One

Monoclonal Antibody Therapies against Anthrax

(2011) Zhaochun Chen et al.   Toxins

Anthrax Toxin Targeting of Myeloid Cells through the CMG2 Receptor Is Essential for Establishment of Bacillus anthracis Infections in Mice

(2010) Shihui Liu et al.   Cell Host & Microbe

Camelid single domain antibodies (VHHs) as neuronal cell intrabody binding agents and inhibitors of Clostridium botulinum neurotoxin (BoNT) proteases

(2010) Jacqueline M. Tremblay et al.   TOXICON

Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment

(2010) Mahtab Moayeri et al.   PLoS Pathogens

Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom

(2009) Rahma Ben Abderrazek et al.   BIOCHEMICAL JOURNAL

Novel Chimpanzee/Human Monoclonal Antibodies That Neutralize Anthrax Lethal Factor, and Evidence for Possible Synergy with Anti-Protective Antigen Antibody

(2009) Z. Chen et al.   INFECTION AND IMMUNITY

Efficient Serum Clearance of Botulinum Neurotoxin Achieved Using a Pool of Small Antitoxin Binding Agents

(2009) J. Sepulveda et al.   INFECTION AND IMMUNITY

Receptors of anthrax toxin and cell entry

(2009) Gisou van der Goot et al.   MOLECULAR ASPECTS OF MEDICINE

Cellular and systemic effects of anthrax lethal toxin and edema toxin

(2009) Mahtab Moayeri et al.   MOLECULAR ASPECTS OF MEDICINE

General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold

(2008) Cécile Vincke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI′

(2008) Issam Hmila et al.   MOLECULAR IMMUNOLOGY