Monoclonal Antibody Therapies against Anthrax

Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice

(2011) Laith Altaweel et al.   CRITICAL CARE MEDICINE

Anthrax Toxin Targeting of Myeloid Cells through the CMG2 Receptor Is Essential for Establishment of Bacillus anthracis Infections in Mice

(2010) Shihui Liu et al.   Cell Host & Microbe

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

(2010) Martina Beltramello et al.   Cell Host & Microbe

Vaccination of Rhesus Macaques with the Anthrax Vaccine Adsorbed Vaccine Produces a Serum Antibody Response That Effectively Neutralizes Receptor-Bound Protective Antigen In Vitro

(2010) K. H. Clement et al.   Clinical and Vaccine Immunology

Neutralizing Monoclonal Antibody to Edema Toxin and Its Effect on Murine Anthrax

(2010) L. Winterroth et al.   INFECTION AND IMMUNITY

Anthrax toxin-neutralizing antibody reconfigures the protective antigen heptamer into a supercomplex

(2010) M. Radjainia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule

(2010) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Chimpanzee/Human Monoclonal Antibodies That Neutralize Anthrax Lethal Factor, and Evidence for Possible Synergy with Anti-Protective Antigen Antibody

(2009) Z. Chen et al.   INFECTION AND IMMUNITY

Receptors of anthrax toxin and cell entry

(2009) Gisou van der Goot et al.   MOLECULAR ASPECTS OF MEDICINE

Cellular and systemic effects of anthrax lethal toxin and edema toxin

(2009) Mahtab Moayeri et al.   MOLECULAR ASPECTS OF MEDICINE

Raxibacumab for the Treatment of Inhalational Anthrax

(2009) Thi-Sau Migone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Isolation and Chimerization of a Highly Neutralizing Antibody Conferring Passive Protection against Lethal Bacillus anthracis Infection

(2009) Ronit Rosenfeld et al.   PLoS One

Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding

(2009) Z. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA