Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways

Trans-Blood Brain Barrier Delivery of Dopamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Rats

(2015) Richa Pahuja et al.   ACS Nano

Even free radicals should follow some rules: A Guide to free radical research terminology and methodology

(2015) Henry Jay Forman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bisphenol-A Mediated Inhibition of Hippocampal Neurogenesis Attenuated by Curcumin via Canonical Wnt Pathway

(2015) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Bisphenol-A Affects Male Fertility via Fertility-related Proteins in Spermatozoa

(2015) Md Saidur Rahman et al.   Scientific Reports

LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease

(2015) Michelle Rothaug et al.   Acta Neuropathologica Communications

A novel link between autophagy and the ubiquitin-proteasome system

(2014) Viktor I. Korolchuk et al.   Autophagy

BECN1 is involved in the initiation of mitophagy

(2014) Vinay Choubey et al.   Autophagy

AMP-activated protein kinase is involved in induction of protective autophagy in astrocytes exposed to oxygen-glucose deprivation

(2014) Bożena Gabryel et al.   CELL BIOLOGY INTERNATIONAL

High-Mobility Group Box 1 Is Dispensable for Autophagy, Mitochondrial Quality Control, and Organ Function In Vivo

(2014) Peter Huebener et al.   Cell Metabolism

Autophagy in arsenic carcinogenesis

(2014) Yuanlin Qi et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

High-fat diet aggravates glucose homeostasis disorder caused by chronic exposure to bisphenol A

(2014) Shibin Ding et al.   JOURNAL OF ENDOCRINOLOGY

Melatonin ameliorates oxidative stress, modulates death receptor pathway proteins, and protects the rat cerebrum against bisphenol-A-induced apoptosis

(2014) Mohamed A. El-Missiry et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway

(2014) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Bisphenol-A Impairs Myelination Potential During Development in the Hippocampus of the Rat Brain

(2014) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Loss of PINK1 Impairs Stress-Induced Autophagy and Cell Survival

(2014) Dajana Parganlija et al.   PLoS One

Bisphenol A regulation of testicular endocrine function in male rats is affected by diet

(2014) Manjunatha K. Nanjappa et al.   TOXICOLOGY LETTERS

TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain

(2014) A Pla et al.   Cell Death & Disease

Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor

(2014) J Ma et al.   Cell Death & Disease

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

(2013) Shashi Kant Tiwari et al.   ACS Nano

Keeping the engine clean

(2013) Michelangelo Campanella et al.   Autophagy

Dynamin 1-like-dependent mitochondrial fission initiates overactive mitophagy in the hepatotoxicity of cadmium

(2013) Huifeng Pi et al.   Autophagy

Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers

(2013) Sovan Sarkar   BIOCHEMICAL SOCIETY TRANSACTIONS

Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism

(2013) Manindra Nath Tiwari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagic Processes in Yeast: Mechanism, Machinery and Regulation

(2013) F. Reggiori et al.   GENETICS

Autophagy: A critical regulator of cellular metabolism and homeostasis

(2013) Stefan W. Ryter et al.   MOLECULES AND CELLS

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy Defect Is Associated with Low Glucose-Induced Apoptosis in 661W Photoreceptor Cells

(2013) Delphine Balmer et al.   PLoS One

Autophagy and apoptosis dysfunction in neurodegenerative disorders

(2013) Saeid Ghavami et al.   PROGRESS IN NEUROBIOLOGY

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Impairment of Atg5-Dependent Autophagic Flux Promotes Paraquat- and MPP+-Induced Apoptosis But Not Rotenone or 6-Hydroxydopamine Toxicity

(2013) Aracely Garcia-Garcia et al.   TOXICOLOGICAL SCIENCES

An appetite for destruction

(2012) Jeroen Poels et al.   Autophagy

Autophagy is a protective response to ethanol neurotoxicity

(2012) Gang Chen et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease

(2012) Rajnish Kumar Chaturvedi et al.   HUMAN MOLECULAR GENETICS

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Bisphenol A, an endocrine-disrupting chemical, and brain development

(2012) Kyoko Itoh et al.   NEUROPATHOLOGY

Neurotoxic Effects of Bisphenol AF on Calcium-Induced ROS and MAPKs

(2012) Soyoung Lee et al.   NEUROTOXICITY RESEARCH

Bisphenol A Induces Hepatotoxicity through Oxidative Stress in Rat Model

(2012) Zeinab K. Hassan et al.   Oxidative Medicine and Cellular Longevity

Bisphenol A Alters n-6 Fatty Acid Composition and Decreases Antioxidant Enzyme Levels in Rat Testes: A LC-QTOF-Based Metabolomics Study

(2012) Minjian Chen et al.   PLoS One

Prenatal Carbofuran Exposure Inhibits Hippocampal Neurogenesis and Causes Learning and Memory Deficits in Offspring

(2012) Divya Mishra et al.   TOXICOLOGICAL SCIENCES

Prooxidant actions of bisphenol A (BPA) phenoxyl radicals: implications to BPA-related oxidative stress and toxicity

(2012) Sainath Babu et al.   TOXICOLOGY MECHANISMS AND METHODS

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

Mitochondria removal by autophagy

(2011) Ke Wang et al.   Autophagy

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy

(2011) Mantong Zhao et al.   Cell Metabolism

Exposure to bisphenol A appears to impair hippocampal neurogenesis and spatial learning and memory

(2011) Mi Eun Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effect of N-acetylcysteine on bisphenol A-induced cognitive dysfunction and oxidative stress in rats

(2011) Seema Jain et al.   FOOD AND CHEMICAL TOXICOLOGY

Neurotoxicity of Endocrine Disruptors: Possible Involvement in Brain Development and Neurodegeneration

(2011) Yoshinori Masuo et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

Prenatal exposure to bisphenol A and phthalates and infant neurobehavior

(2011) Kimberly Yolton et al.   NEUROTOXICOLOGY AND TERATOLOGY

AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

(2011) T. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dose-dependent behavioral disturbances after a single neonatal Bisphenol A dose

(2011) Henrik Viberg et al.   TOXICOLOGY

Rat hyperactivity by bisphenol A, but not by its derivatives, 3-hydroxybisphenol A or bisphenol A 3,4-quinone

(2011) Masami Ishido et al.   TOXICOLOGY LETTERS

Exposure to dibenzofuran triggers autophagy in lung cells

(2011) Filipe V. Duarte et al.   TOXICOLOGY LETTERS

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals

(2010) Yukiko Minamiyama et al.   FREE RADICAL RESEARCH

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

Endocrine disruptors and childhood social impairment

(2010) Amir Miodovnik et al.   NEUROTOXICOLOGY

The Association of AMPK with ULK1 Regulates Autophagy

(2010) Jong Woo Lee et al.   PLoS One

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Bisphenol-A rapidly promotes dynamic changes in hippocampal dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation of NMDA receptor subunit NR2B

(2010) Xiaohong Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Far-red fluorescent tags for protein imaging in living tissues

(2009) Dmitry Shcherbo et al.   BIOCHEMICAL JOURNAL

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

AMPK in the brain: its roles in energy balance and neuroprotection

(2009) Gabriele V. Ronnett et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy and cell death in model organisms

(2008) N Kourtis et al.   CELL DEATH AND DIFFERENTIATION

Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation

(2008) Jessica E. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling pathways of bisphenol A-induced apoptosis in hippocampal neuronal cells: Role of calcium-induced reactive oxygen species, mitogen-activated protein kinases, and nuclear factor-κB

(2008) Soyoung Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

AMPK and Raptor: Matching Cell Growth to Energy Supply

(2008) D. Grahame Hardie   MOLECULAR CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Autophagy as an ultrastructural marker of heavy metal toxicity in human cord blood hematopoietic stem cells

(2008) Mario Di Gioacchino et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons

(2007) Hoa H. Le et al.   TOXICOLOGY LETTERS