Novel genetic tools to tackle c-di-GMP-dependent signalling inPseudomonas aeruginosa

Specific gamma-aminobutyrate chemotaxis in pseudomonads with different lifestyle

(2015) Jose Antonio Reyes-Darias et al.   MOLECULAR MICROBIOLOGY

Pseudomonas aeruginosabiofilm infections: From molecular biofilm biology to new treatment possibilities

(2014) Tim Tolker-Nielsen   APMIS

The art of antibacterial warfare: Deception through interference with quorum sensing–mediated communication

(2014) Giordano Rampioni et al.   BIOORGANIC CHEMISTRY

Targeting virulence: can we make evolution-proof drugs?

(2014) Richard C. Allen et al.   NATURE REVIEWS MICROBIOLOGY

The Periplasmic Protein TolB as a Potential Drug Target in Pseudomonas aeruginosa

(2014) Alessandra Lo Sciuto et al.   PLoS One

The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability

(2013) Davide Antoniani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cyclic di-GMP signalling and the regulation of bacterial virulence

(2013) R. P. Ryan   MICROBIOLOGY-SGM

Applying insights from biofilm biology to drug development — can a new approach be developed?

(2013) Thomas Bjarnsholt et al.   NATURE REVIEWS DRUG DISCOVERY

Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy

(2013) Valentina Stelitano et al.   NUCLEIC ACIDS RESEARCH

A New Transcriptional Repressor of the Pseudomonas aeruginosa Quorum Sensing Receptor Gene lasR

(2013) Francesca Longo et al.   PLoS One

Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain

(2013) Giorgio Giardina et al.   PLoS One

New Life for an Old Drug: the Anthelmintic Drug Niclosamide Inhibits Pseudomonas aeruginosa Quorum Sensing

(2012) F. Imperi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of Small Molecules That Antagonize Diguanylate Cyclase Enzymes To Inhibit Biofilm Formation

(2012) Karthik Sambanthamoorthy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fluorescence-Based Reporter for Gauging Cyclic Di-GMP Levels in Pseudomonas aeruginosa

(2012) Morten T. Rybtke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Small molecule control of bacterial biofilms

(2012) Roberta J. Worthington et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

International Nosocomial Infection Control Consortium (INICC) report, data summary of 36 countries, for 2004-2009

(2011) Victor D. Rosenthal et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Identification of a Novel Benzimidazole That Inhibits Bacterial Biofilm Formation in a Broad-Spectrum Manner

(2011) Karthik Sambanthamoorthy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A multitask biosensor for micro-volumetric detection of N-3-oxo-dodecanoyl-homoserine lactone quorum sensing signal

(2011) Francesco Massai et al.   BIOSENSORS & BIOELECTRONICS

Modulation of Pseudomonas aeruginosa Biofilm Dispersal by a Cyclic-Di-GMP Phosphodiesterase with a Putative Hypoxia-Sensing Domain

(2010) S. An et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate

(2010) Christian Spangler et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Cell-Based Assays for High-Throughput Screening

(2010) W. Frank An et al.   MOLECULAR BIOTECHNOLOGY

Pseudomonas aeruginosauses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix

(2010) Bradley R. Borlee et al.   MOLECULAR MICROBIOLOGY

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Tyrosine phosphatase TpbA of Pseudomonas aeruginosa controls extracellular DNA via cyclic diguanylic acid concentrations

(2010) Akihiro Ueda et al.   Environmental Microbiology Reports

YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa

(2010) Jacob G. Malone et al.   PLoS Pathogens

Monitoring of diguanylate cyclase activity and of cyclic-di-GMP biosynthesis by whole-cell assays suitable for high-throughput screening of biofilm inhibitors

(2009) Davide Antoniani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Pseudomonas aeruginosa Rugose Small-Colony Variants Have Adaptations That Likely Promote Persistence in the Cystic Fibrosis Lung

(2009) M. Starkey et al.   JOURNAL OF BACTERIOLOGY

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

The impact of natural products upon modern drug discovery

(2008) A Ganesan   CURRENT OPINION IN CHEMICAL BIOLOGY

Positively regulated bacterial expression systems

(2008) Trygve Brautaset et al.   Microbial Biotechnology