Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration

Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction

(2014) Jonathan Pitcher et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

(2014) Javier Becerril-Ortega et al.   NEUROBIOLOGY OF AGING

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

(2014) Liviu Vanoaica et al.   PLoS One

Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase

(2014) A. G. Frey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of human substantia nigra identifies novel candidates involved in Parkinson's disease pathogenesis

(2014) Virginie Licker et al.   PROTEOMICS

H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice

(2014) Gregory M. Vercellotti et al.   Frontiers in Pharmacology

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

(2014) Sonia Levi et al.   Frontiers in Pharmacology

Biology and Genetics of Prions Causing Neurodegeneration

(2013) Stanley B. Prusiner   Annual Review of Genetics

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

(2013) David Devos et al.   ANTIOXIDANTS & REDOX SIGNALING

Brain Iron Homeostasis: From Molecular Mechanisms To Clinical Significance and Therapeutic Opportunities

(2013) Neena Singh et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of AMP-Activated Protein Kinase in Ferritin H Gene Expression by Resveratrol in Human T Cells

(2013) Kenta Iwasaki et al.   BIOCHEMISTRY

Oxidative damage of DNA induced by the reaction of methylglyoxal with lysine in the presence of ferritin

(2013) Sung Ho An et al.   BMB Reports

Ferritin: The Protein Nanocage and Iron Biomineral in Health and in Disease

(2013) Elizabeth C. Theil   INORGANIC CHEMISTRY

Each Member of the Poly-r(C)-binding Protein 1 (PCBP) Family Exhibits Iron Chaperone Activity toward Ferritin

(2013) Sebastien Leidgens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

(2013) Abolfazl Zarjou et al.   JOURNAL OF CLINICAL INVESTIGATION

Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome

(2013) Anna Cozzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protective effect of mitochondrial ferritin on cytosolic iron dysregulation induced by doxorubicin in HeLa cells

(2013) Emiliano Cocco et al.   MOLECULAR BIOLOGY REPORTS

Ferritin light chain interacts with PEN-2 and affects γ-secretase activity

(2013) Xinxin Li et al.   NEUROSCIENCE LETTERS

Mobilization of Stored Iron in Mammals: A Review

(2013) Maria Linder   Nutrients

Mitochondrial Ferritin Attenuates β-Amyloid-Induced Neurotoxicity: Reduction in Oxidative Damage Through the Erk/P38 Mitogen-Activated Protein Kinase Pathways

(2012) Wen-Shuang Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Metabolic Adaptation to Tissue Iron Overload Confers Tolerance to Malaria

(2012) Raffaella Gozzelino et al.   Cell Host & Microbe

Neuroferritinopathy: Update on Clinical Features and Pathogenesis

(2012) Alisdair McNeill et al.   CURRENT DRUG TARGETS

Survivin inhibition by an interacting recombinant peptide, derived from the human ferritin heavy chain, impedes tumor cell growth

(2012) Astrid Weiss et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Ferritin Heavy Chain Is the Host Factor Responsible for HCV-Induced Inhibition of apoB-100 Production and Is Required for Efficient Viral Infection

(2012) Carmine Mancone et al.   JOURNAL OF PROTEOME RESEARCH

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

(2012) Baruch E. Bulvik et al.   PLoS One

Activation of the HIF Prolyl Hydroxylase by the Iron Chaperones PCBP1 and PCBP2

(2011) Anjali Nandal et al.   Cell Metabolism

The role of metallobiology and amyloid-β peptides in Alzheimer’s disease

(2011) Blaine R. Roberts et al.   JOURNAL OF NEUROCHEMISTRY

Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells

(2011) T. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains

(2011) Ajay Singh et al.   NEUROBIOLOGY OF DISEASE

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

Expression and Localization of Mitochondrial Ferritin mRNA in Alzheimer's Disease Cerebral Cortex

(2011) Ligang Wang et al.   PLoS One

Characterization of mitochondrial ferritin-deficient mice

(2010) Thomas B. Bartnikas et al.   AMERICAN JOURNAL OF HEMATOLOGY

Neuroprotective Mechanism of Mitochondrial Ferritin on 6-Hydroxydopamine–Induced Dopaminergic Cell Damage: Implication for Neuroprotection in Parkinson's Disease

(2010) Zhen-Hua Shi et al.   ANTIOXIDANTS & REDOX SIGNALING

Lysosomal Proteolysis Is the Primary Degradation Pathway for Cytosolic Ferritin and Cytosolic Ferritin Degradation Is Necessary for Iron Exit

(2010) Yinghui Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Could a dysfunction of ferritin be a determinant factor in the aetiology of some neurodegenerative diseases?

(2010) Carmen Quintana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

(2010) Paolo Arosio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Ferritin-like superfamily: Evolution of the biological iron storeman from a rubrerythrin-like ancestor

(2010) Simon C. Andrews   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The iron redox and hydrolysis chemistry of the ferritins

(2010) Fadi Bou-Abdallah   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Serum ferritin: Past, present and future

(2010) Wei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanism of Cardioprotection by Early Ischemic Preconditioning

(2010) Xiulan Yang et al.   CARDIOVASCULAR DRUGS AND THERAPY

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption

(2010) Liviu Vanoaica et al.   Cell Metabolism

Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress

(2010) K. Hailemariam et al.   JOURNAL OF CELL SCIENCE

Iron and reactive oxygen species activity in parkinsonian substantia nigra

(2010) Anna Wypijewska et al.   PARKINSONISM & RELATED DISORDERS

Electrochemical detection of natural DNA damage induced by ferritin/ascobic acid/H2O2 system and amplification of DNA damage by endonuclease Fpg

(2009) Yi Liu et al.   BIOSENSORS & BIOELECTRONICS

Specific iron chelators determine the route of ferritin degradation

(2009) I. De Domenico et al.   BLOOD

Chronic expression of H-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for Parkinson's disease

(2009) Deepinder Kaur et al.   BRAIN RESEARCH

A new missense mutation in the L ferritin coding sequence associated with elevated levels of glycosylated ferritin in serum and absence of iron overload

(2009) C. Kannengiesser et al.   HAEMATOLOGICA

Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage

(2009) Deepak Darshan et al.   HEPATOLOGY

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene

(2009) Ana G. Barbeito et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial Ferritin in the Substantia Nigra in Restless Legs Syndrome

(2009) Amanda M. Snyder et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Morphine Increases Brain Levels of Ferritin Heavy Chain Leading to Inhibition of CXCR4-Mediated Survival Signaling in Neurons

(2009) R. Sengupta et al.   JOURNAL OF NEUROSCIENCE

Cysteine Oxidation Regulates the RNA-Binding Activity of Iron Regulatory Protein 2

(2009) K. B. Zumbrennen et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of the Tumor Suppressor PTEN in Antioxidant Responsive Element-mediated Transcription and Associated Histone Modifications

(2009) Kensuke Sakamoto et al.   MOLECULAR BIOLOGY OF THE CELL

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

(2009) Anna Cozzi et al.   NEUROBIOLOGY OF DISEASE

Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport

(2009) Ajay Singh et al.   PLoS One

Ferritin enhances salsolinol-mediated DNA strand breakage: Protection by carnosine and related compounds

(2009) Jung Hoon Kang   TOXICOLOGY LETTERS

Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders

(2009) Ajay Singh et al.   PLoS Pathogens

Iron, the substantia nigra and related neurological disorders

(2008) Amanda M. Snyder et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Adiponectin Upregulates Ferritin Heavy Chain in Skeletal Muscle Cells

(2008) Y. Ikegami et al.   DIABETES

Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress

(2008) Elizabeth L. MacKenzie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent process

(2008) Michael A.J. Zieger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

(2008) A. Campanella et al.   HUMAN MOLECULAR GENETICS

Iron-mediated Aggregation and a Localized Structural Change Characterize Ferritin from a Mutant Light Chain Polypeptide That Causes Neurodegeneration

(2008) Martin A. Baraibar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heart protection by ischemic preconditioning: A novel pathway initiated by iron and mediated by ferritin

(2008) Mordechai Chevion et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Expression of a Mutant Form of the Ferritin Light Chain Gene Induces Neurodegeneration and Iron Overload in Transgenic Mice

(2008) R. Vidal et al.   JOURNAL OF NEUROSCIENCE

Comparative Structural and Chemical Studies of Ferritin Cores with Gradual Removal of their Iron Contents

(2008) Natividad Gálvez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Cytosolic Iron Chaperone That Delivers Iron to Ferritin

(2008) H. Shi et al.   SCIENCE

Ischemic preconditioning of the rat retina: Protective role of ferritin

(2007) Alexey Obolensky et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gated pores in the ferritin protein nanocage

(2007) Elizabeth C. Theil et al.   INORGANICA CHIMICA ACTA