Overexpression of ribosome recycling factor is responsible for improvement of nucleotide antibiotic-toyocamycin in Streptomyces diastatochromogenes 1628

Repression of Antibiotic Downregulator WblA by AdpA in Streptomyces coelicolor

(2013) Han-Na Lee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Improvement of gougerotin and nikkomycin production by engineering their biosynthetic gene clusters

(2013) Deyao Du et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Development of Intergeneric Conjugal Gene Transfer System in Streptomyces diastatochromogenes 1628 and Its Application for Improvement of Toyocamycin Production

(2013) Zheng Ma et al.   CURRENT MICROBIOLOGY

Application of a combined approach involving classical random mutagenesis and metabolic engineering to enhance FK506 production in Streptomyces sp. RM7011

(2012) SangJoon Mo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of xylanase by an alkaline-tolerant marine-derived Streptomyces viridochromogenes strain and improvement by ribosome engineering

(2012) Zhuo Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces, Revealed the Extent and Complexity of the AdpA Regulatory Network

(2012) A. Higo et al.   DNA RESEARCH

Increasing the success rate of lantibiotic drug discovery by Synthetic Biology

(2012) Manuel Montalbán-López et al.   Expert Opinion on Drug Discovery

Three pathway-specific regulators control streptolydigin biosynthesis in Streptomyces lydicus

(2012) C. Gomez et al.   MICROBIOLOGY-SGM

Toward steadfast growth of antibiotic research in China: From natural products to engineered biosynthesis

(2011) Qianjin Kang et al.   BIOTECHNOLOGY ADVANCES

The Level of AdpA Directly Affects Expression of Developmental Genes in Streptomyces coelicolor

(2011) Marcin Wolański et al.   JOURNAL OF BACTERIOLOGY

An Orphan Histidine Kinase, OhkA, Regulates Both Secondary Metabolism and Morphological Differentiation in Streptomyces coelicolor

(2011) Y. Lu et al.   JOURNAL OF BACTERIOLOGY

Enhanced Flavonoid Production in Streptomyces venezuelae via Metabolic Engineering

(2011) Sung Ryeol Park   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus

(2011) Akiyoshi Higo et al.   MOLECULAR MICROBIOLOGY

7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine

(2011) Ugo Battaglia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Screening for improved activity of a transglutaminase from Streptomyces mobaraensis created by a novel rational mutagenesis and random mutagenesis

(2010) Keiichi Yokoyama et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genome-wide inference of regulatory networks in Streptomyces coelicolor

(2010) Marlene Castro-Melchor et al.   BMC GENOMICS

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

(2010) Juan-Francisco Martín et al.   CURRENT OPINION IN MICROBIOLOGY

Overexpression of ribosome recycling factor causes increased production of avermectin in Streptomyces avermitilis strains

(2010) Lili Li et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth

(2010) Chris D. Den Hengst et al.   MOLECULAR MICROBIOLOGY

Increased product formation induced by a directed secondary substrate limitation in a batch Hansenula polymorpha culture

(2009) Kirsten Kottmeier et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus

(2009) H. Hara et al.   MICROBIOLOGY-SGM

The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis inStreptomyces ansochromogenes

(2009) Yuanyuan Pan et al.   MOLECULAR MICROBIOLOGY

Deciphering Deazapurine Biosynthesis: Pathway for Pyrrolopyrimidine Nucleosides Toyocamycin and Sangivamycin

(2008) Reid M. McCarty et al.   CHEMISTRY & BIOLOGY

Structural Insights into Ribosome Recycling Factor Interactions with the 70S Ribosome

(2008) Raj D. Pai et al.   JOURNAL OF MOLECULAR BIOLOGY

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

(2008) Carlos Olano et al.   METABOLIC ENGINEERING

Identification of TmcN as a pathway-specific positive regulator of tautomycetin biosynthesis in Streptomyces sp. CK4412

(2008) Y.-A. Hur et al.   MICROBIOLOGY-SGM