Improvement of gougerotin and nikkomycin production by engineering their biosynthetic gene clusters

Cloning, Heterologous Expression, and Characterization of the Gene Cluster Required for Gougerotin Biosynthesis

(2013) Guoqing Niu et al.   CHEMISTRY & BIOLOGY

The construction of a library of synthetic promoters revealed some specific features of strong Streptomyces promoters

(2011) Nicolas Seghezzi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Improvement of antibiotic productivity by knock-out of dauW in Streptomyces coeruleobidus

(2011) Tianjie Yuan et al.   MICROBIOLOGICAL RESEARCH

Use of an inducible promoter for antibiotic production in a heterologous host

(2010) Volker Dangel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production

(2010) Guojian Liao et al.   Microbial Cell Factories

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

(2010) Juan Pablo Gomez-Escribano et al.   Microbial Biotechnology

Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in Streptomyces ansochromogenes

(2009) Guojian Liao et al.   Microbial Cell Factories

polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis

(2009) R. Li et al.   MICROBIOLOGY-SGM

The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis

(2009) Jia Guo et al.   MOLECULAR GENETICS AND GENOMICS

The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis inStreptomyces ansochromogenes

(2009) Yuanyuan Pan et al.   MOLECULAR MICROBIOLOGY

Enhanced Heterologous Production of Desosaminyl Macrolides and Their Hydroxylated Derivatives by Overexpression of the pikD Regulatory Gene in Streptomyces venezuelae

(2008) W. S. Jung et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

CabC, an EF-Hand Calcium-Binding Protein, Is Involved in Ca2+-Mediated Regulation of Spore Germination and Aerial Hypha Formation in Streptomyces coelicolor

(2008) S.-L. Wang et al.   JOURNAL OF BACTERIOLOGY