Endoplasmic Reticulum Stress and Nox-Mediated Reactive Oxygen Species Signaling in the Peripheral Vasculature: Potential Role in Hypertension

Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

(2012) Augusto C. Montezano et al.   ANNALS OF MEDICINE

Production of H2O2 in the Endoplasmic Reticulum Promotes In Vivo Disulfide Bond Formation

(2012) Éva Margittai et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic Reticulum Stress Is Involved in Cardiac Damage and Vascular Endothelial Dysfunction in Hypertensive Mice

(2012) Modar Kassan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metabolic Syndrome, Insulin Resistance, and Roles of Inflammation – Mechanisms and Therapeutic Targets

(2012) Giulio R. Romeo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The chemical chaperone 4-phenylbutyric acid attenuates pressure-overload cardiac hypertrophy by alleviating endoplasmic reticulum stress

(2012) Chang Sik Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

(2012) Suneng Fu et al.   Cell Metabolism

MCP-1 Induced Protein Promotes Adipogenesis via Oxidative Stress, Endoplasmic Reticulum Stress and Autophagy

(2012) Craig Younce et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Attenuating Endoplasmic Reticulum Stress as a Novel Therapeutic Strategy in Pulmonary Hypertension

(2012) Peter Dromparis et al.   CIRCULATION

Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System

(2012) Bernard Lassègue et al.   CIRCULATION RESEARCH

Diabetes and Hypertension: Is There a Common Metabolic Pathway?

(2012) Bernard M. Y. Cheung et al.   Current Atherosclerosis Reports

Deletion of p47 phox attenuates the progression of diabetic nephropathy and reduces the severity of diabetes in the Akita mouse

(2012) G. C. Liu et al.   DIABETOLOGIA

Protein disulfide isomerase in redox cell signaling and homeostasis

(2012) Francisco R.M. Laurindo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase

(2012) Jeffrey G. Dickhout et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic reticulum stress and hypertension — a new paradigm?

(2012) Alyssa H. Hasty et al.   JOURNAL OF CLINICAL INVESTIGATION

ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension

(2012) Colin N. Young et al.   JOURNAL OF CLINICAL INVESTIGATION

New insights into ER stress-induced insulin resistance

(2012) Mélissa Flamment et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolic syndrome: its history, mechanisms, and limitations

(2011) Eiji Oda   ACTA DIABETOLOGICA

Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders

(2011) Lale Ozcan et al.   Annual Review of Medicine

Endothelial Nox4 NADPH Oxidase Enhances Vasodilatation and Reduces Blood Pressure In Vivo

(2011) Robin Ray et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An Emerging Role of Degrading Proteinases in Hypertension and the Metabolic Syndrome: Autodigestion and Receptor Cleavage

(2011) Geert W. Schmid-Schönbein   CURRENT HYPERTENSION REPORTS

Protein export at the ER: loading big collagens into COPII carriers

(2011) Vivek Malhotra et al.   EMBO JOURNAL

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2

(2011) Gábor Csányi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox signaling in cardiac myocytes

(2011) Celio X.C. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Trimer hydroxylated quinone derived from apocynin targets cysteine residues of p47phox preventing the activation of human vascular NADPH oxidase

(2011) Mauricio Mora-Pale et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

Protein disulfide isomerase redox-dependent association with p47phox : evidence for an organizer role in leukocyte NADPH oxidase activation

(2011) Antonio Marcus de A. Paes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Protein Disulfide Isomerase and Host-Pathogen Interaction

(2011) Beatriz S. Stolf et al.   TheScientificWorldJOURNAL

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

ER Stress and Its Functional Link to Mitochondria: Role in Cell Survival and Death

(2011) J. D. Malhotra et al.   Cold Spring Harbor Perspectives in Biology

Molecular Mechanisms Regulating Oxidative Activity of the Ero1 Family in the Endoplasmic Reticulum

(2010) Timothy J. Tavender et al.   ANTIOXIDANTS & REDOX SIGNALING

SnapShot: The Unfolded Protein Response

(2010) R. Luke Wiseman et al.   CELL

Advanced Oxidation Protein Products Induce Inflammatory Response and Insulin Resistance in Cultured Adipocytes via Induction of Endoplasmic Reticulum Stress

(2010) Qiu Gen Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

(2010) Tetsuo Minamino et al.   CIRCULATION RESEARCH

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

Role of the adaptive immune system in hypertension

(2010) David G Harrison et al.   CURRENT OPINION IN PHARMACOLOGY

Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum

(2010) Timothy J Tavender et al.   EMBO JOURNAL

Oxidative folding in the endoplasmic reticulum: Towards a multiple oxidant hypothesis?

(2010) Éva Margittai et al.   FEBS LETTERS

NADPH oxidases in cardiovascular disease

(2010) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis

(2010) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Regulation of basal cellular physiology by the homeostatic unfolded protein response

(2010) D. Thomas Rutkowski et al.   JOURNAL OF CELL BIOLOGY

Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation

(2010) R.-F. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin

(2010) Ester Zito et al.   MOLECULAR CELL

Global Noncommunicable Diseases — Where Worlds Meet

(2010) K.M. Venkat Narayan et al.   NEW ENGLAND JOURNAL OF MEDICINE

PARM-1 Is an Endoplasmic Reticulum Molecule Involved in Endoplasmic Reticulum Stress-Induced Apoptosis in Rat Cardiac Myocytes

(2010) Koji Isodono et al.   PLoS One

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance

(2009) Mitsunori Nomura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Transforming growth factor-β signaling in hypertensive remodeling of porcine aorta

(2009) Natasa Popovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum

(2009) Silvia Senesi et al.   BIOLOGICAL CHEMISTRY

Chronic treatment with pravastatin prevents early cardiovascular changes in spontaneously hypertensive rats

(2009) M Kassan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

(2009) Alicia N. Lyle et al.   CIRCULATION RESEARCH

Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

(2009) Mona Sedeek et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages

(2009) Célio X. C. Santos et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

(2008) Masuko Ushio-Fukai   ANTIOXIDANTS & REDOX SIGNALING

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition

(2008) T. Schluter et al.   CARDIOVASCULAR RESEARCH

Real-Time Redox Measurements during Endoplasmic Reticulum Stress Reveal Interlinked Protein Folding Functions

(2008) Philip I. Merksamer et al.   CELL

GPCR signalling in hypertension: role of GRKs

(2008) David M. Harris et al.   CLINICAL SCIENCE

Chronic insulin treatment causes insulin resistance in 3T3-L1 adipocytes through oxidative stress

(2008) Xuemei Ge et al.   FREE RADICAL RESEARCH

Basal Levels of eIF2α Phosphorylation Determine Cellular Antioxidant Status by Regulating ATF4 and xCT Expression

(2008) Jan Lewerenz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypertension as part of the metabolic syndrome

(2008) B M Y Cheung   JOURNAL OF HUMAN HYPERTENSION

Membrane phospholipid synthesis and endoplasmic reticulum function

(2008) Paolo Fagone et al.   JOURNAL OF LIPID RESEARCH

The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis

(2008) Yasuyo Ariyama et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The earliest fossil record of the animals and its significance

(2008) G. E Budd   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH oxidases in lung biology and pathology: Host defense enzymes, and more

(2007) Albert van der Vliet   FREE RADICAL BIOLOGY AND MEDICINE

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION