Metabolic Syndrome, Insulin Resistance, and Roles of Inflammation – Mechanisms and Therapeutic Targets

The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes

(2013) Allison B. Goldfine   ANNALS OF INTERNAL MEDICINE

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice

(2010) M. E. Shaul et al.   DIABETES

TNF-α Antagonism with Etanercept Decreases Glucose and Increases the Proportion of High Molecular Weight Adiponectin in Obese Subjects with Features of the Metabolic Syndrome

(2010) Takara L. Stanley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice

(2009) Kazue Ohmura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity

(2009) Carine Duffaut et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages and Adipocytes in Human Obesity: Adipose Tissue Gene Expression and Insulin Sensitivity During Calorie Restriction and Weight Stabilization

(2009) F. Capel et al.   DIABETES

Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

(2009) C. M. Larsen et al.   DIABETES CARE

MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4himonocytes in obesity

(2009) Daniel J. Westcott et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

The role of interleukins in insulin resistance and type 2 diabetes mellitus

(2009) Bruno Fève et al.   Nature Reviews Endocrinology

Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals

(2008) David Patsouris et al.   Cell Metabolism

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

(2008) V. Bourlier et al.   CIRCULATION

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES

The Adipocyte as an Endocrine Cell

(2008) Nils Halberg et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Cytokine Signaling Modules in Inflammatory Responses

(2008) John J. O'Shea et al.   IMMUNITY

Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ−/−, PPARδ−/−, PPARγδ−/−, or LXRαβ−/−bone marrow

(2008) Chaitra Marathe et al.   JOURNAL OF LIPID RESEARCH

Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

(2008) Vered Elgazar-Carmon et al.   JOURNAL OF LIPID RESEARCH

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity

(2008) Sara N. Vallerie et al.   PLoS One

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark