Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase

Gene Expression and Genetic Variation in Response to Endoplasmic Reticulum Stress in Human Cells

(2010) Beth A. Dombroski et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ancient origin of the CTH alelle carrying the c.200C>T (p.T67I) variant in patients with cystathioninuria

(2010) C Espinós et al.   CLINICAL GENETICS

Effects of Homocysteine-Lowering With Folic Acid Plus Vitamin B12vs Placebo on Mortality and Major Morbidity in Myocardial Infarction Survivors

(2010)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response

(2010) Souvik Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury

(2010) Isao Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment

(2010) Kenneth N. Maclean et al.   MOLECULAR GENETICS AND METABOLISM

Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment

(2010) Kenneth N. Maclean et al.   MOLECULAR GENETICS AND METABOLISM

Cystathionine γ-lyase: Clinical, metabolic, genetic, and structural studies

(2009) Jan P. Kraus et al.   MOLECULAR GENETICS AND METABOLISM

Kinetic Properties of Polymorphic Variants and Pathogenic Mutants in Human Cystathionine γ-Lyase†

(2008) Weidong Zhu et al.   BIOCHEMISTRY

Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice

(2008) Ji Zhou et al.   FASEB JOURNAL

Mutations in cystathionine β-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans

(2008) Hieronim Jakubowski et al.   FASEB JOURNAL

Effect of Folic Acid and B Vitamins on Risk of Cardiovascular Events and Total Mortality Among Women at High Risk for Cardiovascular Disease

(2008) Christine M. Albert et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Basal Levels of eIF2α Phosphorylation Determine Cellular Antioxidant Status by Regulating ATF4 and xCT Expression

(2008) Jan Lewerenz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo

(2008) Philipp S. Lange et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE