NADPH Oxidases in Redox Regulation of Cell Adhesion and Migration

LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation

(2013) Heather Menden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A 28-kDa Splice Variant of NADPH Oxidase-4 Is Nuclear-Localized and Involved in Redox Signaling in Vascular Cells

(2013) Narayana Anilkumar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

1a,25-Dihydroxycholecalciferol (Vitamin D3) Induces NO-Dependent Endothelial Cell Proliferation and Migration in a Three-Dimensional Matrix

(2013) Claudio Molinari et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy

(2013) Jennifer L. Wilkinson-Berka et al.   CLINICAL SCIENCE

A review of the influence of growth factors and cytokines in in vitro human keratinocyte migration

(2013) Philip V. Peplow et al.   CYTOKINE

NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis

(2013) Claudia Goettsch et al.   JOURNAL OF CLINICAL INVESTIGATION

Nox2 Is Required for Macrophage Chemotaxis towards CSF-1

(2013) Sanjay Chaubey et al.   PLoS One

Regulation of Monocyte Adhesion and Migration by Nox4

(2013) Chi Fung Lee et al.   PLoS One

Targeting tumor cell motility as a strategy against invasion and metastasis

(2013) Alan Wells et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

(2012) Augusto C. Montezano et al.   ANNALS OF MEDICINE

Oxidation of 2-Cys Peroxiredoxins in Human Endothelial Cells by Hydrogen Peroxide, Hypochlorous Acid, and Chloramines

(2012) Melissa M. Stacey et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of SERCA2 Is Required for Vascular Endothelial Growth Factor-Induced Signaling and Endothelial Cell Migration

(2012) Alicia M. Evangelista et al.   ANTIOXIDANTS & REDOX SIGNALING

Protection against vascular aging in Nox2-deficient mice: Impact on endothelial progenitor cells and reparative neovascularization

(2012) Julie Turgeon et al.   ATHEROSCLEROSIS

Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE−/− mice

(2012) Gillian Douglas et al.   CARDIOVASCULAR RESEARCH

NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

(2012) Chih-Chung Lin et al.   Cell Communication and Signaling

Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells

(2012) I-Ta Lee et al.   Cell Communication and Signaling

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Activation of thromboxane receptor modulates interleukin-1β-induced monocyte adhesion―A novel role of Nox1

(2012) Hossein Bayat et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration

(2012) Alicia M. Evangelista et al.   FREE RADICAL BIOLOGY AND MEDICINE

TG-interacting factor-induced superoxide production from NADPH oxidase contributes to the migration/invasion of urothelial carcinoma

(2012) Huei-Sheng Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Nox4 in murine models of kidney disease

(2012) Andrea Babelova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Integrin α7β1 is a redox-regulated target of hydrogen peroxide in vascular smooth muscle cell adhesion

(2012) Flávia Figueiredo de Rezende et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells

(2012) Howard E. Boudreau et al.   FREE RADICAL BIOLOGY AND MEDICINE

The influence of reactive oxygen species on cell cycle progression in mammalian cells

(2012) Eline Hendrike Verbon et al.   GENE

NOX5 in Human Spermatozoa

(2012) Boris Musset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Disulfide Isomerase Is Required for Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Migration, Nox1 NADPH Oxidase Expression, and RhoGTPase Activation

(2012) Luciana A. Pescatore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH oxidase-mediated redox signal contributes to lipoteichoic acid-induced MMP-9 upregulation in brain astrocytes

(2012) Hsi-Lung Hsieh et al.   Journal of Neuroinflammation

TLR-4 Signalling Accelerates Colon Cancer Cell Adhesion via NF-κB Mediated Transcriptional Up-Regulation of Nox-1

(2012) D. Peter O'Leary et al.   PLoS One

Critical role of fractalkine (CX3CL1) in cigarette smoke-induced mononuclear cell adhesion to the arterial endothelium

(2012) Cristina Rius et al.   THORAX

Stop the Flow: A Paradigm for Cell Signaling Mediated by Reactive Oxygen Species in the Pulmonary Endothelium

(2011) Elizabeth A. Browning et al.   Annual Review of Physiology

Src Phosphorylation of Endothelial Cell Surface Intercellular Adhesion Molecule-1 Mediates Neutrophil Adhesion and Contributes to the Mechanism of Lung Inflammation

(2011) Guoquan Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

α1AMP-Activated Protein Kinase Preserves Endothelial Function During Chronic Angiotensin II Treatment by Limiting Nox2 Upregulation

(2011) Swenja Schuhmacher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells

(2011) Mahandranauth A. Chetram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rac regulates PtdInsP3 signaling and the chemotactic compass through a redox-mediated feedback loop

(2011) J. W. P. Kuiper et al.   BLOOD

NOX2-derived reactive oxygen species are crucial for CD29-induced pro-survival signalling in cardiomyocytes

(2011) Berit I. Rosc-Schlüter et al.   CARDIOVASCULAR RESEARCH

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

(2011) Siobhan M. Craige et al.   CIRCULATION

Orai1 and CRAC Channel Dependence of VEGF-Activated Ca 2+ Entry and Endothelial Tube Formation

(2011) Jing Li et al.   CIRCULATION RESEARCH

Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues

(2011) Wei-Jian Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of NADPH Oxidase 1 Increases Intracellular Calcium and Migration of Smooth Muscle Cells

(2011) Matthew C. Zimmerman et al.   HYPERTENSION

Regulation of protein tyrosine phosphatases by reversible oxidation

(2011) Arne Östman et al.   JOURNAL OF BIOCHEMISTRY

Platelet-derived Growth Factor (PDGF) Regulates Slingshot Phosphatase Activity via Nox1-dependent Auto-dephosphorylation of Serine 834 in Vascular Smooth Muscle Cells

(2011) Mithunan Maheswaranathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological Relevance of Antioxid/Redox Genes; Learning from Genetically Modified Animals Guest Editor: Junichi Fujii Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme

(2011) Masato Katsuyama et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Oxidation of Myofibrillar Proteins in Human Heart Failure

(2011) Marcella Canton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Do Hv1 proton channels regulate the ionic and redox homeostasis of phagosomes?

(2011) Antoun El Chemaly et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

(2011) Sarah Garrido-Urbani et al.   PLoS One

Hepatocyte Growth Factor Induces a Proangiogenic Phenotype and Mobilizes Endothelial Progenitor Cells by Activating Nox2

(2010) Katrin Schröder et al.   ANTIOXIDANTS & REDOX SIGNALING

Vascular Cell Adhesion Molecule-1 Expression and Signaling During Disease: Regulation by Reactive Oxygen Species and Antioxidants

(2010) Joan M. Cook-Mills et al.   ANTIOXIDANTS & REDOX SIGNALING

Relationship between Oxidative Stress and Inflammatory Cytokines in Diabetic Nephropathy

(2010) Ahmed A. Elmarakby et al.   Cardiovascular Therapeutics

Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death

(2010) Chi Fung Lee et al.   CIRCULATION RESEARCH

Upregulation of Nox4 by TGFβ1 Oxidizes SERCA and Inhibits NO in Arterial Smooth Muscle of the Prediabetic Zucker Rat

(2010) XiaoYong Tong et al.   CIRCULATION RESEARCH

Rac1-Dependent Intracellular Superoxide Formation Mediates Vascular Endothelial Growth Factor–Induced Placental Angiogenesisin Vitro

(2010) Su-min Li et al.   ENDOCRINOLOGY

Phosphorylation of NADPH oxidase activator 1 (NOXA1) on serine 282 by MAP kinases and on serine 172 by protein kinase C and protein kinase A prevents NOX1 hyperactivation

(2010) Yolande Kroviarski et al.   FASEB JOURNAL

Src redox regulation: Again in the front line

(2010) Elisa Giannoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox2-based NADPH oxidase mediates HIV-1 Tat-induced up-regulation of VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes

(2010) Ha Yong Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells

(2010) Chiang-Wen Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets

(2010) J. F. ARTHUR et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

(2010) M M Reddy et al.   LEUKEMIA

ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion

(2010) Nicolas Tobar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

c-Src–Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)–Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells

(2010) Davide Gianni et al.   MOLECULAR BIOLOGY OF THE CELL

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nox5 and the Regulation of Cellular Function

(2009) David J.R. Fulton   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeting and Regulation of Reactive Oxygen Species Generation by Nox Family NADPH Oxidases

(2009) Thomas L. Leto et al.   ANTIOXIDANTS & REDOX SIGNALING

Receptor Activation of NADPH Oxidases

(2009) Andreas Petry et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NADPH Oxidase Nox2 Is Required for Hypoxia-Induced Mobilization of Endothelial Progenitor Cells

(2009) Katrin Schröder et al.   CIRCULATION RESEARCH

Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells

(2009) Alicia N. Lyle et al.   CIRCULATION RESEARCH

NADPH oxidases are responsible for the failure of nitric oxide to inhibit migration of smooth muscle cells exposed to high glucose

(2009) XiaoYong Tong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of NADPH oxidase-2 in lipopolysaccharide-induced matrix metalloproteinase expression and cell migration

(2009) So-Yeon Kim et al.   IMMUNOLOGY AND CELL BIOLOGY

Reactive Oxygen Generated by NADPH Oxidase 1 (Nox1) Contributes to Cell Invasion by Regulating Matrix Metalloprotease-9 Production and Cell Migration

(2009) Masahiro Shinohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH Oxidase 1 Controls the Persistence of Directed Cell Migration by a Rho-Dependent Switch of  2/ 3 Integrins

(2009) A. Sadok et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural Insights into Nox4 and Nox2: Motifs Involved in Function and Cellular Localization

(2009) K. von Lohneysen et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of Structural Elements in Nox1 and Nox4 Controlling Localization and Activity

(2008) Ina Helmcke et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells

(2008) Srikanth Pendyala et al.   ANTIOXIDANTS & REDOX SIGNALING

The Role of Cellular Adaptation to Mechanical Forces in Atherosclerosis

(2008) Cornelia Hahn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

(2008) Katrin Schröder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

(2008) Masuko Ushio-Fukai et al.   CANCER LETTERS

Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells

(2008) D. Meng et al.   CARDIOVASCULAR RESEARCH

Role of Nox2-Based NADPH Oxidase in Bone Marrow and Progenitor Cell Function Involved in Neovascularization Induced by Hindlimb Ischemia

(2008) Norifumi Urao et al.   CIRCULATION RESEARCH

Macrophages Generate Reactive Oxygen Species in Response to Minimally Oxidized Low-Density Lipoprotein

(2008) Yun Soo Bae et al.   CIRCULATION RESEARCH

Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II–Induced Adventitial Myofibroblast Migration

(2008) Mounir J. Haurani et al.   HYPERTENSION

Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease

(2008) Tomasz J. Guzik et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Toll-like receptor 9-stimulated monocyte chemoattractant protein-1 is mediated via JNK-cytosolic phospholipase A2-ROS signaling

(2007) Jin-Gu Lee et al.   CELLULAR SIGNALLING