Redox Control of Platelet Functions in Physiology and Pathophysiology

The sirtuins, oxidative stress and aging: an emerging link

(2016) Philip I. Merksamer et al.   Aging-US

Superactivated Platelets

(2013) Marshall Mazepa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular mechanisms of platelet P2Y12receptor regulation

(2013) Margaret R. Cunningham et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Platelet mitochondrial function: from regulation of thrombosis to biomarker of disease

(2013) Sergey Zharikov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Selective triggering of platelet apoptosis, platelet activation or both

(2013) Armen V. Gyulkhandanyan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ib  and Fc RIIa in immune thrombocytopenia

(2013) R. T. Urbanus et al.   HAEMATOLOGICA

Pathophysiology and management of primary immune thrombocytopenia

(2013) Hirokazu Kashiwagi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Protease-activated Receptor 1 (PAR1) and PAR4 Heterodimers Are Required for PAR1-enhanced Cleavage of PAR4 by α-Thrombin

(2013) Amal Arachiche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dengue induces platelet activation, mitochondrial dysfunction and cell death through mechanisms that involve DC-SIGN and caspases

(2013) E. D. Hottz et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The role of mitochondrial permeability transition pore in regulating the shedding of the platelet GPIbα ectodomain

(2013) Zhicheng Wang et al.   PLATELETS

Antioxidant Status and Oxidative Stress in Patients with Chronic ITP

(2013) C.-Q. Jin et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Cell Death in Immune Thrombocytopenia: Novel Insights and Perspectives

(2013) Stephan von Gunten et al.   SEMINARS IN HEMATOLOGY

Role of erythrocytes and platelets in the hypercoagulable status in polycythemia vera through phosphatidylserine exposure and microparticle generation

(2013) Chunyan Gao et al.   THROMBOSIS AND HAEMOSTASIS

Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health

(2012) Tiago R. Figueira et al.   ANTIOXIDANTS & REDOX SIGNALING

Two Types of Procoagulant Platelets Are Formed Upon Physiological Activation and Are Controlled by Integrin α IIb β 3

(2012) Nikolay N. Topalov et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Identification of Different Proaggregatory Abilities of Activated Platelet Subpopulations

(2012) Alena O. Yakimenko et al.   BIOPHYSICAL JOURNAL

The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner

(2012) D Vara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Overview of Pyridine Nucleotides Review Series

(2012) Michinari Nakamura et al.   CIRCULATION RESEARCH

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood

(2012) Stephanie M. Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo

(2012) Elizabeth D. Hood et al.   JOURNAL OF CONTROLLED RELEASE

Fibroblast autophagy in fibrotic disorders

(2012) Domenico Del Principe et al.   JOURNAL OF PATHOLOGY

Characterizations and proteome analysis of platelet-free plasma-derived microparticles in β-thalassemia/hemoglobin E patients

(2012) Porntip Chaichompoo et al.   Journal of Proteomics

ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways

(2012) J. F. ARTHUR et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Crocin, a dietary additive protects platelets from oxidative stress-induced apoptosis and inhibits platelet aggregation

(2012) R. M. Thushara et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Fractalkine – a local inflammatory marker aggravating platelet activation at the vulnerable plaque

(2012) Ulrike Flierl et al.   THROMBOSIS AND HAEMOSTASIS

Platelet-leukocyte crosstalk: Linking proinflammatory responses to procoagulant state

(2012) Mehran Ghasemzadeh et al.   THROMBOSIS RESEARCH

Intraplatelet Oxidative/Nitrative Stress: Inductors, Consequences, and Control

(2012) Nicoleta Alexandru et al.   TRENDS IN CARDIOVASCULAR MEDICINE

JAK2 the future: therapeutic strategies for JAK-dependent malignancies

(2012) Lindsay M. LaFave et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Redox Regulation of Mitochondrial Function

(2011) Diane E. Handy et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of vanin-1 and oxidative stress-related pathways in distinguishing acute and chronic pediatric ITP

(2011) B. Zhang et al.   BLOOD

Apoptosis in the anucleate platelet

(2011) Valery Leytin   BLOOD REVIEWS

Platelet apoptosis in paediatric immune thrombocytopenia is ameliorated by intravenous immunoglobulin

(2011) Jeannine Winkler et al.   BRITISH JOURNAL OF HAEMATOLOGY

Role of reactive oxygen and nitrogen species in the vascular responses to inflammation

(2011) Peter R. Kvietys et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thrombocytopenia in HIV-Infected Patients

(2011) Francielle Garcia Nascimento et al.   INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION

Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1 -Rich Microparticles

(2011) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

Platelets: a critical link between inflammation and microvascular dysfunction

(2011) Karen Y. Stokes et al.   JOURNAL OF PHYSIOLOGY-LONDON

Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: a cross-talk between mtThiol, Ca2+, and ROS

(2011) Brijesh Kumar Singh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Reduced antioxidant capacities in platelets from patients with autoimmune thrombocytopenia purpura (ITP)

(2011) Julian Kamhieh-Milz et al.   PLATELETS

Microparticles: a critical component in the nexus between inflammation, immunity, and thrombosis

(2011) Olivier Morel et al.   Seminars in Immunopathology

Piecing Together the Humoral and Cellular Mechanisms of Immune Thrombocytopenia

(2011) Lisa Toltl et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Blood platelet biochemistry

(2011) Katleen Broos et al.   THROMBOSIS RESEARCH

Doxorubicin-Induced Platelet Procoagulant Activities: An Important Clue for Chemotherapy-Associated Thrombosis

(2011) Se-Hwan Kim et al.   TOXICOLOGICAL SCIENCES

Trans-Plasma Membrane Electron Transport in Mammals: Functional Significance in Health and Disease

(2010) Domenico Del Principe et al.   ANTIOXIDANTS & REDOX SIGNALING

Cellular Mechanisms Underlying the Formation of Circulating Microparticles

(2010) Olivier Morel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Specific binding of hypochlorite-oxidized HDL to platelet CD36 triggers proinflammatory and procoagulant effects

(2010) Alice Assinger et al.   ATHEROSCLEROSIS

Oxidative stress and defective platelet apoptosis in naïve patients with Kawasaki disease

(2010) Elisabetta Straface et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NAD: A master regulator of transcription

(2010) Sanchari Ghosh et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Triple play of H pylori in ITP

(2010) Y. S. Ahn   BLOOD

Acidic Ca2+ stores in platelets

(2010) J.A. Rosado   CELL CALCIUM

Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

Secondary necrosis: The natural outcome of the complete apoptotic program

(2010) Manuel T. Silva   FEBS LETTERS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential expression of apoptosis-related genes from death receptor pathway in chronic myeloproliferative diseases

(2010) R. Tognon et al.   JOURNAL OF CLINICAL PATHOLOGY

Nix Nought Nothing: Fairy tale or real deal

(2010) Gerald W. Dorn   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nitric oxide-sensitive guanylyl cyclase is the only nitric oxide receptor mediating platelet inhibition

(2010) O. DANGEL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity

(2010) Janahan Dharmarajah et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Formation of procoagulant microparticles and properties

(2010) Jean-Marie Freyssinet et al.   THROMBOSIS RESEARCH

Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and  2 integrin-dependent cell clearance program

(2009) N. Maugeri et al.   BLOOD

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

(2009) S. M. Schoenwaelder et al.   BLOOD

Mitochondria regulate platelet metamorphosis induced by opsonized zymosan A - activation and long-term commitment to cell death

(2009) Paola Matarrese et al.   FEBS Journal

Novel molecules in calcium signaling in platelets

(2009) W. BERGMEIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The structure and function of platelet integrins

(2009) J. S. BENNETT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The glycoprotein Ibα-von Willebrand factor interaction induces platelet apoptosis

(2009) S. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protein deacetylation by SIRT1: An emerging key post-translational modification in metabolic regulation

(2009) Jiujiu Yu et al.   PHARMACOLOGICAL RESEARCH

Reactive oxygen species as universal constraints in life-history evolution

(2009) D. K. Dowling et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X1-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y1 and P2Y12 receptor activation

(2009) Caroline Skoglund et al.   THROMBOSIS AND HAEMOSTASIS

Redox Control of Platelet Function

(2008) David W. Essex   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Stress and Platelets

(2008) Jane E. Freedman   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activity of the BH3 mimetic ABT-737 on polycythemia vera erythroid precursor cells

(2008) A. Zeuner et al.   BLOOD

Recruitment of T cells into bone marrow of ITP patients possibly due to elevated expression of VLA-4 and CX3CR1

(2008) B. Olsson et al.   BLOOD

Glutathione and apoptosis

(2008) Magdalena L. Circu et al.   FREE RADICAL RESEARCH

Thromboxane A2: Physiology/pathophysiology, cellular signal transduction and pharmacology

(2008) Norimichi Nakahata   PHARMACOLOGY & THERAPEUTICS

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING