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Title
The osteoblastic niche in the context of multiple myeloma
Authors
Keywords
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Journal
Annals of the New York Academy of Sciences
Volume 1335, Issue 1, Pages 45-62
Publisher
Wiley
Online
2014-11-26
DOI
10.1111/nyas.12578
References
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Related references
Note: Only part of the references are listed.- Osteoblastic niche supports the growth of quiescent multiple myeloma cells
- (2014) Z. Chen et al. BLOOD
- Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model
- (2014) M. R. Reagan et al. BLOOD
- Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells
- (2014) J. Wang et al. BLOOD
- Parathyroid hormone receptor mediates the anti-myeloma effect of proteasome inhibitors
- (2014) Maurizio Zangari et al. BONE
- The bone marrow stromal compartment in multiple myeloma patients retains capability for osteogenic differentiationin vitro: defining the stromal defect in myeloma
- (2014) Deepika Kassen et al. BRITISH JOURNAL OF HAEMATOLOGY
- Preclinical Activity of the Oral Proteasome Inhibitor MLN9708 in Myeloma Bone Disease
- (2014) A. Garcia-Gomez et al. CLINICAL CANCER RESEARCH
- Carfilzomib promotes the osteogenic differentiation potential of mesenchymal stem cells derived from myeloma patients by inhibiting notch1 activity in vitro
- (2014) Yali Li et al. LEUKEMIA RESEARCH
- Direct measurement of local oxygen concentration in the bone marrow of live animals
- (2014) Joel A. Spencer et al. NATURE
- The bone marrow niche for haematopoietic stem cells
- (2014) Sean J. Morrison et al. NATURE
- Therapeutic modulation of Notch signalling — are we there yet?
- (2014) Emma R. Andersson et al. NATURE REVIEWS DRUG DISCOVERY
- Romosozumab in Postmenopausal Women with Low Bone Mineral Density
- (2014) Michael R. McClung et al. NEW ENGLAND JOURNAL OF MEDICINE
- Osx-Cre Targets Multiple Cell Types besides Osteoblast Lineage in Postnatal Mice
- (2014) Jianquan Chen et al. PLoS One
- The effects of bortezomib on bone disease in patients with multiple myeloma
- (2013) Mohamad Mohty et al. CANCER
- BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression
- (2013) Aldo M. Roccaro et al. JOURNAL OF CLINICAL INVESTIGATION
- Notch-directed microenvironment reprogramming in myeloma: a single path to multiple outcomes
- (2013) M Colombo et al. LEUKEMIA
- Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1
- (2013) L Mirandola et al. LEUKEMIA
- Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction
- (2013) P Storti et al. LEUKEMIA
- WNT signaling in bone homeostasis and disease: from human mutations to treatments
- (2013) Roland Baron et al. NATURE MEDICINE
- Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients
- (2013) Song Xu et al. PLoS One
- Multiple functions of the noncanonical Wnt pathway
- (2013) Eva Gómez-Orte et al. TRENDS IN GENETICS
- Myelopoiesis is regulated by osteocytes through Gs -dependent signaling
- (2012) K. Fulzele et al. BLOOD
- miR-155 modulates TNF-α-inhibited osteogenic differentiation by targeting SOCS1 expression
- (2012) Tingting Wu et al. BONE
- Hematopoietic stem cell fate decisions are regulated by Wnt antagonists: Comparisons and current controversies
- (2012) Corey J. Cain et al. EXPERIMENTAL HEMATOLOGY
- miR-182 is a negative regulator of osteoblast proliferation, differentiation, and skeletogenesis through targeting FoxO1
- (2012) Kyoung Min Kim et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients is associated with a blockade in the deactivation of the Notch signaling pathway
- (2012) S Xu et al. LEUKEMIA
- Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation
- (2012) N Giuliani et al. LEUKEMIA
- Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells
- (2012) M Bolzoni et al. LEUKEMIA
- The Notch signalling system: recent insights into the complexity of a conserved pathway
- (2012) K. G. Guruharsha et al. NATURE REVIEWS GENETICS
- Upregulation of miR-22 Promotes Osteogenic Differentiation and Inhibits Adipogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stem Cells by Repressing HDAC6 Protein Expression
- (2012) Shan Huang et al. STEM CELLS AND DEVELOPMENT
- Impairment in Immunomodulatory Function of Mesenchymal Stem Cells from Multiple Myeloma Patients
- (2011) Bingzong Li et al. ARCHIVES OF MEDICAL RESEARCH
- A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor
- (2011) Kyeong Lee et al. ARCHIVES OF PHARMACAL RESEARCH
- Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells
- (2011) C. Schaniel et al. BLOOD
- Bone and the hematopoietic niche: a tale of two stem cells
- (2011) P. Bianco BLOOD
- Autophagy in mineralizing tissues: Microenvironmental perspectives
- (2011) Vickram Srinivas et al. CELL CYCLE
- Constitutively active PTH/PTHrP receptor specifically expressed in osteoblasts enhances bone formation induced by bone marrow ablation
- (2011) Noriaki Ono et al. JOURNAL OF CELLULAR PHYSIOLOGY
- MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma
- (2011) V Ramakrishnan et al. LEUKEMIA
- Dynamic niches in the origination and differentiation of haematopoietic stem cells
- (2011) Leo D. Wang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches
- (2010) I. G. Winkler et al. BLOOD
- Osteoblast function in myeloma
- (2010) G. David Roodman BONE
- Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line
- (2010) Shannon M. Buckley et al. EXPERIMENTAL HEMATOLOGY
- Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
- (2010) Desmond Padhi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Glucocorticoid-induced autophagy in osteocytes
- (2010) Xuechun Xia et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The amazing osteocyte
- (2010) Lynda F Bonewald JOURNAL OF BONE AND MINERAL RESEARCH
- Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients
- (2010) N Giuliani et al. LEUKEMIA
- Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells
- (2010) S Colla et al. LEUKEMIA
- Osteoblastogenesis and tumor growth in myeloma
- (2010) Shmuel Yaccoby LEUKEMIA & LYMPHOMA
- Consequences of Daily Administered Parathyroid Hormone on Myeloma Growth, Bone Disease, and Molecular Profiling of Whole Myelomatous Bone
- (2010) Angela Pennisi et al. PLoS One
- Is autophagy a double-edged sword for the heart?
- (2009) N. Gurusamy et al. ACTA PHYSIOLOGICA HUNGARICA
- Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells
- (2009) Hideaki Nakajima et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
- (2009) M. Fulciniti et al. BLOOD
- Osteocyte apoptosis and control of bone resorption following ovariectomy in mice
- (2009) K.B. Emerton et al. BONE
- Notch signaling and the bone marrow hematopoietic stem cell niche
- (2009) Jonathan M. Weber et al. BONE
- Noncanonical Wnt Signaling Orchestrates Early Developmental Events toward Hematopoietic Cell Fate from Human Embryonic Stem Cells
- (2009) Kausalia Vijayaragavan et al. Cell Stem Cell
- Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells
- (2009) Jonas Renström et al. Cell Stem Cell
- Osteogenic differentiation of mesenchymal stem cells in multiple myeloma: Identification of potential therapeutic targets
- (2009) Nicola Giuliani et al. EXPERIMENTAL HEMATOLOGY
- Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors
- (2009) M Garayoa et al. LEUKEMIA
- β-Catenin Expression in the Bone Marrow Microenvironment Is Required for Long-Term Maintenance of Primitive Hematopoietic Cells
- (2009) Michael J. Nemeth et al. STEM CELLS
- Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth
- (2008) Y.-W. Qiang et al. BLOOD
- The pathogenesis of the bone disease of multiple myeloma
- (2008) Claire M. Edwards et al. BONE
- BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
- (2008) N. Kamiya et al. DEVELOPMENT
- Teriparatide
- (2008) Stephanie K A Blick et al. DRUGS
- The Signaling Protein Wnt4 Enhances Thymopoiesis and Expands Multipotent Hematopoietic Progenitors through β-Catenin-Independent Signaling
- (2008) Isabelle Louis et al. IMMUNITY
- Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma
- (2008) Deborah J Heath et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase
- (2008) Yan Liu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A RNA antagonist of hypoxia-inducible factor-1 , EZN-2968, inhibits tumor cell growth
- (2008) L. M. Greenberger et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of osteogenic differentiation during skeletal development
- (2007) Zhong-Liang Deng Frontiers in Bioscience-Landmark
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