Dynamic niches in the origination and differentiation of haematopoietic stem cells

Marrow Fat and the Bone Microenvironment: Developmental, Functional, and Pathological Implications

(2012) Clifford J. Rosen et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Biomimetic Platforms for Human Stem Cell Research

(2011) Gordana Vunjak-Novakovic et al.   Cell Stem Cell

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in

(2011) Armin Ehninger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice

(2010) Jay J. Cao et al.   Annals of the New York Academy of Sciences

Cold exposure down-regulates zebrafish hematopoiesis

(2010) Kasem Kulkeaw et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

(2010) S. W. Lane et al.   BLOOD

Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo

(2010) S. Lymperi et al.   BLOOD

Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

(2010) M. Tesio et al.   BLOOD

An in vivo model to study and manipulate the hematopoietic stem cell niche

(2010) J. Song et al.   BLOOD

Hematopoiesis in 3 dimensions: human and murine bone marrow architecture visualized by confocal microscopy

(2010) T. Takaku et al.   BLOOD

A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations

(2010) J. Krosl et al.   BLOOD

Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells

(2010) K. Hosokawa et al.   BLOOD

Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression

(2010) Y.-S. Tzeng et al.   BLOOD

Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells

(2010) Y. Nakamura et al.   BLOOD

Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function

(2010) B. R. Chitteti et al.   BLOOD

Pharmacologic modulation of the calcium-sensing receptor enhances hematopoietic stem cell lodgment in the adult bone marrow

(2010) B. S. Lam et al.   BLOOD

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

(2010) I. G. Winkler et al.   BLOOD

Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis

(2010) Mary Mohrin et al.   Cell Stem Cell

Patient-Specific Pluripotent Stem Cells Become Even More Accessible

(2010) Shinya Yamanaka   Cell Stem Cell

Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow

(2010) Kentaro Hosokawa et al.   Cell Stem Cell

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

(2010) Keiyo Takubo et al.   Cell Stem Cell

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

(2010) Jason M. Butler et al.   Cell Stem Cell

Gene transfer by electroporation into hemogenic endothelium in the avian embryo

(2010) Catalina Ana Rosselló et al.   DEVELOPMENTAL DYNAMICS

Hypoxia mediates low cell-cycle activity and increases the proportion of long-term–reconstituting hematopoietic stem cells during in vitro culture

(2010) Pernilla Eliasson et al.   EXPERIMENTAL HEMATOLOGY

NF-κB-ISGF3 Transcription Factor Cooperation: Coincidence Detector or Memory Chip?

(2010) David E. Levy   IMMUNITY

The Notch pathway in the developing hematopoietic system

(2010) Anna Bigas et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

High fat diet-induced animal model of age-associated obesity and osteoporosis

(2010) Ganesh V. Halade et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Proteomic Analysis of Interstitial Fluid in Bone Marrow Identified That Peroxiredoxin 2 Regulates H2O2Level of Bone Marrow during Aging

(2010) Wei Wang et al.   JOURNAL OF PROTEOME RESEARCH

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

(2010) Hideki Kobayashi et al.   NATURE CELL BIOLOGY

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

(2010) Colleen Delaney et al.   NATURE MEDICINE

Vertebral Bone Marrow Fat Is Positively Associated With Visceral Fat and Inversely Associated With IGF-1 in Obese Women

(2010) Miriam A. Bredella et al.   Obesity

Obesity and the Risk for a Hematological Malignancy: Leukemia, Lymphoma, or Myeloma

(2010) M. A. Lichtman   ONCOLOGIST

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

(2010) Anthony E. Boitano et al.   SCIENCE

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Epidermal Neural Crest Stem Cell (EPI-NCSC)—Mediated Recovery of Sensory Function in a Mouse Model of Spinal Cord Injury

(2010) Yao Fei Hu et al.   Stem Cell Reviews and Reports

WNT Proteins: Environmental Factors Regulating HSC Fate in the Niche

(2009) Tiago C. Luis et al.   Annals of the New York Academy of Sciences

Niche Regulation of Hematopoietic Stem Cells in the Endosteum

(2009) Fumio Arai et al.   Annals of the New York Academy of Sciences

Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling

(2009) M. I. Mascarenhas et al.   BLOOD

Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation

(2009) M. Dominici et al.   BLOOD

Spatial gradients of blood vessels and hematopoietic stem and progenitor cells within the marrow cavities of the human skeleton

(2009) V. A. Bourke et al.   BLOOD

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution

(2009) D. Lewandowski et al.   BLOOD

Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones

(2009) A. Kohler et al.   BLOOD

Notch signaling and the bone marrow hematopoietic stem cell niche

(2009) Jonathan M. Weber et al.   BONE

Ontogeny of haematopoiesis: recent advances and open questions

(2009) Katrin Ottersbach et al.   BRITISH JOURNAL OF HAEMATOLOGY

Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration

(2009) Wolfram Goessling et al.   CELL

Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells

(2009) Andrea T. Hooper et al.   Cell Stem Cell

Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches

(2009) Joy Y Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The hematopoietic stem cell niche: Low in oxygen but a nice place to be

(2009) Pernilla Eliasson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock

(2009) Julia V. Busik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Improved Cutaneous Healing in Diabetic Mice Exposed to Healthy Peripheral Circulation

(2009) Giorgio Pietramaggiori et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

Biomechanical forces promote embryonic haematopoiesis

(2009) Luigi Adamo et al.   NATURE

Designing materials to direct stem-cell fate

(2009) Matthias P. Lutolf et al.   NATURE

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

(2009) Olaia Naveiras et al.   NATURE

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

(2009) C. Chen et al.   Science Signaling

What is the true nature of the osteoblastic hematopoietic stem cell niche?

(2009) Maria Askmyr et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Biophysics and dynamics of natural and engineered stem cell microenvironments

(2009) Albert J. Keung et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Communications between bone cells and hematopoietic stem cells

(2008) R.L. Porter et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

N-Cadherin Expression Level Distinguishes Reserved versus Primed States of Hematopoietic Stem Cells

(2008) Jeffrey S. Haug et al.   Cell Stem Cell

Stem Cell Regulation via Dynamic Interactions of the Nervous and Immune Systems with the Microenvironment

(2008) Asaf Spiegel et al.   Cell Stem Cell

Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo

(2008) Heather E. Fleming et al.   Cell Stem Cell

Aging of hematopoietic stem cells is regulated by the stem cell niche

(2008) Wolfgang Wagner et al.   EXPERIMENTAL GERONTOLOGY

Formation of micronucleated erythrocytes in mouse bone-marrow under conditions of hypothermia is not associated with stimulation of erythropoiesis

(2008) Antonio Guzmán et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Detection of functional haematopoietic stem cell niche using real-time imaging

(2008) Yucai Xie et al.   NATURE

Endochondral ossification is required for haematopoietic stem-cell niche formation

(2008) Charles K. F. Chan et al.   NATURE

Of lineage and legacy: the development of mammalian hematopoietic stem cells

(2008) Elaine Dzierzak et al.   NATURE IMMUNOLOGY

A role for leptin in sustaining lymphopoiesis and myelopoiesis

(2008) K. Claycombe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Bone Marrow Adipocytes Block Granulopoiesis Through Neuropilin-1-Induced Granulocyte Colony-Stimulating Factor Inhibition

(2008) Zakia Belaid-Choucair et al.   STEM CELLS