Regio- and Stereoselective Monoamination of Diketones without Protecting Groups

Stereoselectivity of Four (R)-Selective Transaminases for the Asymmetric Amination of Ketones

(2011) Francesco G. Mutti et al.   ADVANCED SYNTHESIS & CATALYSIS

Enzymatic Asymmetric Synthesis of Enantiomerically Pure Aliphatic, Aromatic and Arylaliphatic Amines with (R)-Selective Amine Transaminases

(2011) Sebastian Schätzle et al.   ADVANCED SYNTHESIS & CATALYSIS

Regio- and Chemoselective Metalation of Arenes and Heteroarenes Using Hindered Metal Amide Bases

(2011) Benjamin Haag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Purification and Characterization of a Novel (S)-Enantioselective Transaminase fromPseudomonas fluorescensKNK08-18 for the Synthesis of Optically Active Amines

(2011) Noriyuki ITO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Process considerations for the asymmetric synthesis of chiral amines using transaminases

(2011) Pär Tufvesson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Aminotransferase-catalyzed asymmetric synthesis of benazepril intermediate

(2011) Bum-Yeol Hwang et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Enzymes in the Synthesis of Glycoconjugates

(2011) Ryan M. Schmaltz et al.   CHEMICAL REVIEWS

Chemoenzymatic Synthesis of Inositols, Conduritols, and Cyclitol Analogues

(2011) Jan Duchek et al.   CHEMICAL REVIEWS

Redox Reactions Catalyzed by Isolated Enzymes

(2011) Daniela Monti et al.   CHEMICAL REVIEWS

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Regioselective enzymatic acylation of complex natural products: expanding molecular diversity

(2011) Javier González-Sabín et al.   CHEMICAL SOCIETY REVIEWS

Free energy analysis of ω-transaminase reactions to dissect how the enzyme controls the substrate selectivity

(2011) Eul-Soo Park et al.   ENZYME AND MICROBIAL TECHNOLOGY

Amination of Ketones by Employing Two New (S)-Selective ω-Transaminases and the His-Tagged ω-TA from Vibrio fluvialis

(2011) Francesco G. Mutti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficient Total Synthesis of (+)-Dihydropinidine, (−)-Epidihydropinidine, and (−)-Pinidinone

(2011) Miroslav Kavala et al.   JOURNAL OF NATURAL PRODUCTS

Catalysis-Based and Protecting-Group-Free Total Syntheses of the Marine Oxylipins Hybridalactone and the Ecklonialactones A, B, and C

(2011) Volker Hickmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

(2011) Sabrina Kille et al.   Nature Chemistry

Synthesis of α,α-Disubstituted Aryl Amines by Rhodium-Catalyzed Amination of Tertiary Allylic Trichloroacetimidates

(2011) Jeffrey S. Arnold et al.   ORGANIC LETTERS

Palladium-/Copper-Catalyzed Regioselective Amination and Chloroamination of Indoles

(2011) Xue-Yuan Liu et al.   ORGANIC LETTERS

Highly Regioselective Amination of Unactivated Alkanes by Hypervalent Sulfonylimino- 3-Bromane

(2011) M. Ochiai et al.   SCIENCE

Efficient one-pot synthesis of functionalized piperidine scaffolds via ZrOCl2·8H2O catalyzed tandem reactions of aromatic aldehydes with amines and acetoacetic esters

(2011) Sarita Mishra et al.   TETRAHEDRON LETTERS

Biocatalysis: Synthesis of Key Intermediates for Development of Pharmaceuticals

(2011) Ramesh N. Patel   ACS Catalysis

Concise Total Synthesis of Sintokamides A, B, and E by a Unified, Protecting-Group-Free Strategy

(2010) Zhenhua Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric, Protecting-Group-Free Total Synthesis of (−)-Englerin A

(2010) Qianghui Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reversed Enantiopreference of an ω-Transaminase by a Single-Point Mutation

(2010) Maria Svedendahl et al.   ChemCatChem

High-Yield Biocatalytic Amination Reactions in Organic Synthesis

(2010) John Ward et al.   CURRENT ORGANIC CHEMISTRY

Rational assignment of key motifs for function guides in silico enzyme identification

(2010) Matthias Höhne et al.   Nature Chemical Biology

Rhodium-Catalyzed Regioselective Amination of Secondary Allylic Trichloroacetimidates with Unactivated Aromatic Amines

(2010) Jeffrey S. Arnold et al.   ORGANIC LETTERS

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Recent developments in regioselective ring opening of aziridines

(2010) Pengfei Lu   TETRAHEDRON

ω-Transaminases for the synthesis of non-racemic α-chiral primary amines

(2010) Dominik Koszelewski et al.   TRENDS IN BIOTECHNOLOGY

Multicomponent Reactions for the Synthesis of Complex Piperidine Scaffolds

(2009) Wei Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic asymmetric amination of carbonyl functional groups - a synthetic biology approach to organic chemistry

(2009) Dunming Zhu et al.   Biotechnology Journal

Synthesis of Optically Active Amines Employing Recombinant ω-Transaminases inE. coliCells

(2009) Dominik Koszelewski et al.   ChemCatChem

Synthesizing our future

(2009) Ryoji Noyori   Nature Chemistry

Protecting-group-free synthesis as an opportunity for invention

(2009) Ian S. Young et al.   Nature Chemistry

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/ω-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

(2009) Mark E. B. Smith et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Efficient Production of Enantiomerically Pure Chiral Amines at Concentrations of 50 g/L Using Transaminases

(2009) Matthew D. Truppo et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Preparation of (R)-Amines from Racemic Amines with an (S)-Amine Transaminase fromBacillus megaterium

(2008) Ronald L. Hanson et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective Syntheses of 2,6-disubstituted Piperidin-3-oles (alkaloid lipids)

(2008) Sofia Koulocheri et al.   CURRENT ORGANIC CHEMISTRY

New opportunities for biocatalysis: making pharmaceutical processes greener

(2008) John M. Woodley   TRENDS IN BIOTECHNOLOGY