MicroRNAs Regulate Mitochondrial Function in Cerebral Ischemia-Reperfusion Injury

Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs

(2015) Tiago Fernandes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Use of microRNAs to Modulate Redox and Immune Response to Stroke

(2015) Yi-Bing Ouyang et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNA-29a induces apoptosis via increasing the Bax:Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis

(2015) Saeideh Jafarinejad-Farsangi et al.   AUTOIMMUNITY

MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke

(2015) Li-Gang Huang et al.   CNS Neuroscience & Therapeutics

Post-stroke treatment with miR-181 antagomir reduces injury and improves long-term behavioral recovery in mice after focal cerebral ischemia

(2015) Li-Jun Xu et al.   EXPERIMENTAL NEUROLOGY

The mitochondrial permeability transition: A current perspective on its identity and role in ischaemia/reperfusion injury

(2015) Andrew P. Halestrap et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-200c Contributes to Injury From Transient Focal Cerebral Ischemia by Targeting Reelin

(2015) Creed M. Stary et al.   STROKE

Protecting the mitochondrial powerhouse

(2015) Morten Scheibye-Knudsen et al.   TRENDS IN CELL BIOLOGY

MicroRNA regulation of mitochondrial and ER stress signaling pathways: implications for lipoprotein metabolism in metabolic syndrome

(2014) Patricia Christian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA-34a induces apoptosis in the human glioma cell line, A172, through enhanced ROS production and NOX2 expression

(2014) San-Zhong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of miR-23b expression and its dual role on ROS production and tumour development

(2014) Massimo Donadelli et al.   CANCER LETTERS

Triiodothyronine Prevents Cardiac Ischemia/Reperfusion Mitochondrial Impairment and Cell Loss by Regulating miR30a/p53 Axis

(2014) Francesca Forini et al.   ENDOCRINOLOGY

Signaling pathways leading to ischemic mitochondrial neuroprotection

(2014) John W. Thompson et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Aberrant miR199a-5p/caveolin1/PPARα axis in hepatic steatosis

(2014) Bo Li et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

miR-134 Regulates Ischemia/Reperfusion Injury-Induced Neuronal Cell Death by Regulating CREB Signaling

(2014) Weidong Huang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MicroRNAs Expression and Function in Cerebral Ischemia Reperfusion Injury

(2014) Yu Di et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Role of mitochondrial calcium uniporter in regulating mitochondrial fission in the cerebral cortexes of living rats

(2014) Nan Liang et al.   JOURNAL OF NEURAL TRANSMISSION

MicroRNA-302b-inhibited E2F3 transcription factor is related to all trans retinoic acid-induced glioma cell apoptosis

(2014) Peng-Hsu Chen et al.   JOURNAL OF NEUROCHEMISTRY

Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene

(2014) Masaki Miyazawa et al.   MOLECULAR BIOLOGY OF THE CELL

Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport

(2014) Chendong Yang et al.   MOLECULAR CELL

MicroRNA-155 induction by Mycobacterium bovis BCG enhances ROS production through targeting SHIP1

(2014) Jinli Wang et al.   MOLECULAR IMMUNOLOGY

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of Downregulation of MicroRNA-181a on H2O2-Induced H9c2 Cell Apoptosis via the Mitochondrial Apoptotic Pathway

(2014) Lei Wang et al.   Oxidative Medicine and Cellular Longevity

miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma

(2014) Angela M. Liu et al.   PLoS One

Brain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice

(2014) Reema Roshan et al.   RNA

Mitochondria: from cell death executioners to regulators of cell differentiation

(2014) Atsuko Kasahara et al.   TRENDS IN CELL BIOLOGY

The Role of microRNAs in Mitochondria: Small Players Acting Wide

(2014) Filipe Duarte et al.   Genes

Mitochondrial reactive oxygen species: A double edged sword in ischemia/reperfusion vs preconditioning

(2014) Theodore Kalogeris et al.   Redox Biology

Hypoxamirs and Mitochondrial Metabolism

(2013) Katherine A. Cottrill et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-145 suppresses ROS-induced Ca2+ overload of cardiomyocytes by targeting CaMKIIδ

(2013) Min-Ji Cha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

microRNAs: Innovative Targets for Cerebral Ischemia and Stroke

(2013) Yi-Bing Ouyang et al.   CURRENT DRUG TARGETS

miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor

(2013) Bo Long et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNAs: potential mediators and biomarkers of diabetic complications

(2013) Mitsuo Kato et al.   FREE RADICAL BIOLOGY AND MEDICINE

NF-κB mediated miR-21 regulation in cardiomyocytes apoptosis under oxidative stress

(2013) C. Wei et al.   FREE RADICAL RESEARCH

Astrocyte-enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia

(2013) Yi-Bing Ouyang et al.   GLIA

MicroRNA-23a Antisense Enhances 5-Fluorouracil Chemosensitivity Through APAF-1/Caspase-9 Apoptotic Pathway in Colorectal Cancer Cells

(2013) Jingli Shang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of microRNA-181 Reduces Forebrain Ischemia-Induced Neuronal Loss

(2013) Jeong-mi Moon et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The p53 Transcription Factor Modulates Microglia Behavior through MicroRNA-Dependent Regulation of c-Maf

(2013) W. Su et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

(2013) Zoltán V. Varga et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-124 (miR-124) Regulates Ku70 Expression and is Correlated with Neuronal Death Induced by Ischemia/Reperfusion

(2013) Fei Zhu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1

(2013) Zhifeng Peng et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Effect of Mitochondrial Calcium Uniporter Opener Spermine on Diazoxide against Focal Cerebral Ischemia—Reperfusion Injury in Rats

(2013) Huanli Dong et al.   Journal of Stroke & Cerebrovascular Diseases

Survival of hypoxic human mesenchymal stem cells is enhanced by a positive feedback loop involving miR-210 and hypoxia-inducible factor 1

(2013) Woochul Chang et al.   Journal of Veterinary Science

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

Proteome Modulation in H9c2 Cardiac Cells by microRNAs miR-378 and miR-378

(2013) Youssef Mallat et al.   MOLECULAR & CELLULAR PROTEOMICS

Synergy of Homocysteine, MicroRNA, and Epigenetics: A Novel Therapeutic Approach for Stroke

(2013) Anuradha Kalani et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective effect of gadolinium: a stretch-activated calcium channel blocker in mouse model of ischemia–reperfusion injury

(2013) Puja Gulati et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Downregulation of miR-133 via MAPK/ERK signaling pathway involved in nicotine-induced cardiomyocyte apoptosis

(2013) Lu Wang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

miR-141 as a regulator of the mitochondrial phosphate carrier (Slc25a3) in the type 1 diabetic heart

(2012) Walter A. Baseler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Biphasic modulation of the mitochondrial electron transport chain in myocardial ischemia and reperfusion

(2012) Hsin-Ling Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNF 

(2012) X. Zhang et al.   CANCER RESEARCH

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

Nuclear miRNA Regulates the Mitochondrial Genome in the Heart

(2012) Samarjit Das et al.   CIRCULATION RESEARCH

MicroRNAs

(2012) Jennifer Sacco et al.   CURRENT OPINION IN LIPIDOLOGY

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death

(2012) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells

(2012) Hirotomo Tanaka et al.   JOURNAL OF NEURO-ONCOLOGY

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Mitochondria: One of the destinations of miRNAs

(2012) Lakshmi Sripada et al.   MITOCHONDRION

Molecular Mechanisms of Ischemia–Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation

(2012) Thomas H. Sanderson et al.   MOLECULAR NEUROBIOLOGY

Autoregulation of microRNA biogenesis by let-7 and Argonaute

(2012) Dimitrios G. Zisoulis et al.   NATURE

Neuronal oxidative stress in acute ischemic stroke: Sources and contribution to cell injury

(2012) Silvia Manzanero et al.   NEUROCHEMISTRY INTERNATIONAL

An Antagomir to MicroRNA Let7f Promotes Neuroprotection in an Ischemic Stroke Model

(2012) Amutha Selvamani et al.   PLoS One

MicroRNA-145 Protects Cardiomyocytes against Hydrogen Peroxide (H2O2)-Induced Apoptosis through Targeting the Mitochondria Apoptotic Pathway

(2012) Ruotian Li et al.   PLoS One

MicroRNA-30b-Mediated Regulation of Catalase Expression in Human ARPE-19 Cells

(2012) Rashidul Haque et al.   PLoS One

Multipolar functions of BCL-2 proteins link energetics to apoptosis

(2012) J. Marie Hardwick et al.   TRENDS IN CELL BIOLOGY

Biogenesis of Mammalian MicroRNAs: A Global View

(2012) Paul Graves et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

miR23b Ameliorates Neuropathic Pain in Spinal Cord by Silencing NADPH Oxidase 4

(2011) Young Bin Im et al.   ANTIOXIDANTS & REDOX SIGNALING

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

miR-497 and miR-302b Regulate Ethanol-induced Neuronal Cell Death through BCL2 Protein and Cyclin D2

(2011) Sanjay Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of mitochondrial activity by miRNAs

(2011) Peifeng Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Up-regulation of the mitochondrial malate dehydrogenase by oxidative stress is mediated by miR-743a

(2011) Qingli Shi et al.   JOURNAL OF NEUROCHEMISTRY

Identification of differentially expressed microRNAs and their PKC-isoform specific gene network prediction during hypoxic pre-conditioning and focal cerebral ischemia of mice

(2011) Cuiying Liu et al.   JOURNAL OF NEUROCHEMISTRY

miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes

(2011) X.-Y. Bai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis

(2011) Maik Hüttemann et al.   MITOCHONDRION

MicroRNA history: Discovery, recent applications, and next frontiers

(2011) Maria I. Almeida et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo

(2011) Yi-Bing Ouyang et al.   NEUROBIOLOGY OF DISEASE

miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia

(2011) C. Siegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microRNA miR-696 regulates PGC-1α in mouse skeletal muscle in response to physical activity

(2010) Wataru Aoi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Cytochrome c is rapidly reduced in the cytosol after mitochondrial outer membrane permeabilization

(2010) Maureen O. Ripple et al.   APOPTOSIS

A potential role for intragenic miRNAs on their hosts' interactome

(2010) Ludwig Hinske et al.   BMC GENOMICS

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

NADPH oxidase 4 is an oncoprotein localized to mitochondria

(2010) Kelly A. Graham et al.   CANCER BIOLOGY & THERAPY

Transcriptional Control of Gene Expression by MicroRNAs

(2010) Basel Khraiwesh et al.   CELL

miR-378 ∗ Mediates Metabolic Shift in Breast Cancer Cells via the PGC-1β/ERRγ Transcriptional Pathway

(2010) Lillian J. Eichner et al.   Cell Metabolism

MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expression

(2010) Liang-Liang Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Regulation of intermediary metabolism by the PKCδ signalosome in mitochondria

(2010) Rebeca Acin-Perez et al.   FASEB JOURNAL

Changes in the expression of mitochondrial peroxiredoxin and thioredoxin in neurons and glia and their protective effects in experimental cerebral ischemic damage

(2010) In Koo Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reperfusion and Neurovascular Dysfunction in Stroke: from Basic Mechanisms to Potential Strategies for Neuroprotection

(2010) Joo Eun Jung et al.   MOLECULAR NEUROBIOLOGY

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

(2010) Jian-Xun Wang et al.   NATURE MEDICINE

miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia

(2010) Ke-Jie Yin et al.   NEUROBIOLOGY OF DISEASE

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression

(2010) Z Chen et al.   ONCOGENE

MicroRNA 128a Increases Intracellular ROS Level by Targeting Bmi-1 and Inhibits Medulloblastoma Cancer Cell Growth by Promoting Senescence

(2010) Sujatha Venkataraman et al.   PLoS One

miR-17* Suppresses Tumorigenicity of Prostate Cancer by Inhibiting Mitochondrial Antioxidant Enzymes

(2010) Yong Xu et al.   PLoS One

MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis

(2010) Betsy T. Kren et al.   RNA Biology

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondria, oxidative metabolism and cell death in stroke

(2009) Neil R. Sims et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNAs as regulators of death receptors signaling

(2009) M Garofalo et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA-15b Modulates Cellular ATP Levels and Degenerates Mitochondria via Arl2 in Neonatal Rat Cardiac Myocytes

(2009) Hitoo Nishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

(2009) Ping Gao et al.   NATURE

Mitochondrial Calcium Transport and Mitochondrial Dysfunction After Global Brain Ischemia in Rat Hippocampus

(2009) Peter Racay et al.   NEUROCHEMICAL RESEARCH

Expression Profile of MicroRNAs in Young Stroke Patients

(2009) Kay Sin Tan et al.   PLoS One

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

MicroRNA-338 Regulates Local Cytochrome c Oxidase IV mRNA Levels and Oxidative Phosphorylation in the Axons of Sympathetic Neurons

(2008) A. Aschrafi et al.   JOURNAL OF NEUROSCIENCE

Discovering microRNAs from deep sequencing data using miRDeep

(2008) Marc R Friedländer et al.   NATURE BIOTECHNOLOGY

MicroRNA detection by northern blotting using locked nucleic acid probes

(2008) Éva Várallyay et al.   Nature Protocols

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution

(2008) Katsutomo Okamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON

MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion

(2008) Kandiah Jeyaseelan et al.   STROKE

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY