Secondary muscle pathology and metabolic dysregulation in adults with cerebral palsy

Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle

(2012) Deborah M. Muoio et al.   Cell Metabolism

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

Toll-like receptors 2 and 4 impair insulin-mediated brain activity by interleukin-6 and osteopontin and alter sleep architecture

(2012) Tina Sartorius et al.   FASEB JOURNAL

Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?

(2012) Bobbi Fleiss et al.   LANCET NEUROLOGY

Are sirtuins viable targets for improving healthspan and lifespan?

(2012) Joseph A. Baur et al.   NATURE REVIEWS DRUG DISCOVERY

Linking mitochondrial bioenergetics to insulin resistance via redox biology

(2012) Kelsey H. Fisher-Wellman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Human obesity is characterized by defective fat storage and enhanced muscle fatty acid oxidation, and trimetazidine gradually counteracts these abnormalities

(2011) Marco Bucci et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial dysfunction and insulin resistance from the outside in: extracellular matrix, the cytoskeleton, and mitochondria

(2011) Dawn K. Coletta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Origins of metabolic complications in obesity

(2011) Bettina Mittendorfer   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The extracellular matrix dimension of skeletal muscle development

(2011) Sólveig Thorsteinsdóttir et al.   DEVELOPMENTAL BIOLOGY

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

(2011) William L. Holland et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Skeletal Muscle Satellite Cells Are Committed to Myogenesis and Do Not Spontaneously Adopt Nonmyogenic Fates

(2011) Jessica D. Starkey et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increasedin vivosarcomere length

(2011) Lucas R. Smith et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Stem cells for skeletal muscle repair

(2011) J. L. Shadrach et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

(2011) Saswata Talukdar et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Adipose proinflammatory cytokine expression through sympathetic system is associated with hyperglycemia and insulin resistance in a rat ischemic stroke model

(2010) Ya-Yu Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Role of Muscle Insulin Resistance in the Pathogenesis of Atherogenic Dyslipidemia and Nonalcoholic Fatty Liver Disease Associated with the Metabolic Syndrome

(2010) François R. Jornayvaz et al.   Annual Review of Nutrition

Muscle insulin resistance: assault by lipids, cytokines and local macrophages

(2010) Girish Kewalramani et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Epidemiology of myosteatosis

(2010) Iva Miljkovic et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Sarcopenic obesity: satellite cells in the aging muscle

(2010) Lars-Eric Thornell   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

MEDICAL AND FUNCTIONAL STATUS OF ADULTS WTH CEREBRAL PALSY

(2010) Kevin P. Murphy et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals

(2010) E. Phielix et al.   DIABETOLOGIA

Minireview: Inflammation and Obesity Pathogenesis: The Hypothalamus Heats Up

(2010) Joshua P. Thaler et al.   ENDOCRINOLOGY

Mechanical work performed by the legs of children with spastic diplegic cerebral palsy

(2010) Max J. Kurz et al.   GAIT & POSTURE

Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals

(2010) Patricia Iozzo et al.   GASTROENTEROLOGY

Adiposity attenuates muscle quality and the adaptive response to resistance exercise in non-obese, healthy adults

(2010) M D Peterson et al.   INTERNATIONAL JOURNAL OF OBESITY

Skeletal Muscle Mitochondria in Insulin Resistance: Differences in IntermyofibrillarVersusSubsarcolemmal Subpopulations and Relationship to Metabolic Flexibility

(2010) Peter Chomentowski et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Tipping the scale: muscle versus fat

(2010) Matthew S. Rodeheffer   NATURE CELL BIOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Multiple Markers of Inflammation and Weight Status: Cross-sectional Analyses Throughout Childhood

(2010) A. C. Skinner et al.   PEDIATRICS

IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKβ and ER Stress Inhibition

(2010) Eduardo R. Ropelle et al.   PLOS BIOLOGY

Adipose tissue distribution is different in type 2 diabetes

(2009) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Longitudinal study of muscle strength, quality, and adipose tissue infiltration

(2009) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

MIF Deficiency Reduces Chronic Inflammation in White Adipose Tissue and Impairs the Development of Insulin Resistance, Glucose Intolerance, and Associated Atherosclerotic Disease

(2009) Lars Verschuren et al.   CIRCULATION RESEARCH

Osteoporosis in adults with cerebral palsy

(2009) KEVIN J SHERIDAN   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Muscle deficits in cerebral palsy and early loss of mobility: can we learn something from our elders?

(2009) ADAM SHORTLAND   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

The potential metabolic consequences of cerebral palsy: inferences from the general population and persons with spinal cord injury

(2009) WILLIAM A BAUMAN   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Health, mortality, and wellness issues in adults with cerebral palsy

(2009) MARGARET A TURK   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes

(2009) H. Hwang et al.   DIABETES

Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality

(2009) Abel Romero-Corral et al.   EUROPEAN HEART JOURNAL

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Endomysial Fibrosis in Duchenne Muscular Dystrophy: A Marker of Poor Outcome Associated With Macrophage Alternative Activation

(2009) Isabelle Desguerre et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

The Effect of Aging on Human Skeletal Muscle Mitochondrial and Intramyocellular Lipid Ultrastructure

(2009) J. D. Crane et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Body Mass Index Measures in Children with Cerebral Palsy Related to Gross Motor Function Classification

(2008) Edward A. Hurvitz et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

Phosphorylation of IRS proteins, insulin action, and insulin resistance

(2008) Sigalit Boura-Halfon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fatigue Resistance During a Voluntary Performance Task Is Associated With Lower Levels of Mobility in Cerebral Palsy

(2008) Noelle G. Moreau et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Inflammation and metabolic disorders

(2008) Mohamad Navab et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Asian Indians Have Enhanced Skeletal Muscle Mitochondrial Capacity to Produce ATP in Association With Severe Insulin Resistance

(2008) K. S. Nair et al.   DIABETES

Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects

(2008) S. M. Reyna et al.   DIABETES

Mitochondrial fitness and insulin sensitivity in humans

(2008) J. Szendroedi et al.   DIABETOLOGIA

Intracellular Lipid Accumulation in Liver and Muscle and the Insulin Resistance Syndrome

(2008) Cristina Lara-Castro et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Alterations in Muscle Attenuation following Detraining and Retraining in Resistance-Trained Older Adults

(2008) Dennis R. Taaffe et al.   GERONTOLOGY

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

Myostatin Directly Regulates Skeletal Muscle Fibrosis

(2008) Zhao Bo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION

Adipose Tissue Infiltration of Skeletal Muscle in Children with Cerebral Palsy

(2008) David L. Johnson et al.   JOURNAL OF PEDIATRICS

Prevalence of Cerebral Palsy in 8-Year-Old Children in Three Areas of the United States in 2002: A Multisite Collaboration

(2008) M. Yeargin-Allsopp et al.   PEDIATRICS

Excessive Adipose Tissue Infiltration in Skeletal Muscle in Individuals With Obesity, Diabetes Mellitus, and Peripheral Neuropathy: Association With Performance and Function

(2008) Tiffany N Hilton et al.   PHYSICAL THERAPY