The Association of Common Variants in PCSK1 With Obesity: A HuGE Review and Meta-Analysis

Conducting Meta-Analyses inRwith themetaforPackage

(2015) Wolfgang Viechtbauer   Journal of Statistical Software

Defective Transport of the Obesity Mutant PC1/3 N222D Contributes to Loss of Function

(2014) Yogikala Prabhu et al.   ENDOCRINOLOGY

A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity

(2014) J Philippe et al.   INTERNATIONAL JOURNAL OF OBESITY

STrengthening the REporting of Genetic Association Studies (STREGA): An Extension of the STROBE Statement

(2013) Julian Little   ANNALS OF INTERNAL MEDICINE

Identification of HKDC1 and BACE2 as Genes Influencing Glycemic Traits During Pregnancy Through Genome-Wide Association Studies

(2013) M. Geoffrey Hayes et al.   DIABETES

Congenital Proprotein Convertase 1/3 Deficiency Causes Malabsorptive Diarrhea and Other Endocrinopathies in a Pediatric Cohort

(2013) Martín G. Martín et al.   GASTROENTEROLOGY

Association of the rs6235 variant in the proprotein convertase subtilisin/kexin type 1 (PCSK1) gene with obesity and related traits in a Taiwanese population

(2013) Tun-Jen Hsiao et al.   GENE

From Diarrhea to Obesity in Prohormone Convertase 1/3 Deficiency

(2013) Robert H.J. Bandsma et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Severe obesity and diabetes insipidus in a patient with PCSK1 deficiency

(2013) Graeme R. Frank et al.   MOLECULAR GENETICS AND METABOLISM

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

(2013) Sonja I Berndt et al.   NATURE GENETICS

Functional Consequences of a Novel Variant of PCSK1

(2013) Lindsay A. Pickett et al.   PLoS One

Contribution of Common PCSK1 Genetic Variants to Obesity in 8,359 Subjects from Multi-Ethnic American Population

(2013) Hélène Choquet et al.   PLoS One

Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci

(2013) Ching-Ti Liu et al.   PLoS Genetics

Polymorphisms in an obesity-related gene (PCSK1) are associated with fat deposition and production traits in Italian heavy pigs

(2012) L. Fontanesi et al.   Animal

Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population

(2012) Bo Xi et al.   CLINICAL ENDOCRINOLOGY

Heritability of body mass index in pre-adolescence, young adulthood and late adulthood

(2012) Cassandra Nan et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

The obesity-related polymorphism PCSK1 rs6235 is associated with essential hypertension in the Han Chinese population

(2012) Xiao-mu Li et al.   HYPERTENSION RESEARCH

Meta-analysis identifies common variants associated with body mass index in east Asians

(2012) Wanqing Wen et al.   NATURE GENETICS

PCSK1 rs6232 Is Associated with Childhood and Adult Class III Obesity in the Mexican Population

(2012) Marisela Villalobos-Comparán et al.   PLoS One

Selection Signature Analysis Implicates the PC1/PCSK1 Region for Chicken Abdominal Fat Content

(2012) Hui Zhang et al.   PLoS One

Performance of statistical methods for meta-analysis when true study effects are non-normally distributed: A comparison between DerSimonian–Laird and restricted maximum likelihood

(2012) Evangelos Kontopantelis et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity

(2011) J. W. M. Creemers et al.   DIABETES

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

(2011) R. J. Strawbridge et al.   DIABETES

The polymorphisms of bovine PCSK1 gene and their associations with growth traits

(2011) Limin Shan et al.   Genes & Genomics

Implication of European-derived adiposity loci in African Americans

(2011) J M Hester et al.   INTERNATIONAL JOURNAL OF OBESITY

Common Variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 Show Evidence of Association With Adult Obesity in the Greek Population

(2011) Konstantinos Rouskas et al.   Obesity

Waist-to-height ratio is a better screening tool than waist circumference and BMI for adult cardiometabolic risk factors: systematic review and meta-analysis

(2011) M. Ashwell et al.   Obesity Reviews

The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status

(2011) Anette P. Gjesing et al.   PLoS One

Childhood obesity and adult morbidities

(2010) Frank M Biro et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Novel Single Nucleotide Polymorphisms of the Caprine PC1 Gene and Association with Growth Traits

(2010) Jiajie Sun et al.   BIOCHEMICAL GENETICS

Association of obesity risk SNPs in PCSK1with insulin sensitivity and proinsulin conversion

(2010) Martin Heni et al.   BMC Medical Genetics

Combined Analyses of 20 Common Obesity Susceptibility Variants

(2010) C. H. Sandholt et al.   DIABETES

Genetic Predisposition to Long-Term Nondiabetic Deteriorations in Glucose Homeostasis: Ten-Year Follow-Up of the GLACIER Study

(2010) F. Renstrom et al.   DIABETES

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Association of PCSK1 rs6234 with Obesity and Related Traits in a Chinese Han Population

(2010) Qibin Qi et al.   PLoS One

Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data

(2009) Byron C Wallace et al.   BMC Medical Research Methodology

Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study

(2009) T. O. Kilpelainen et al.   HUMAN MOLECULAR GENETICS

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB Study

(2009) G H Goossens et al.   INTERNATIONAL JOURNAL OF OBESITY

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Obesity-related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study

(2009) Eva Corpeleijn et al.   Obesity

The epidemiology of obesity: the size of the problem

(2008) W. P. T. James   JOURNAL OF INTERNAL MEDICINE

Common nonsynonymous variants in PCSK1 confer risk of obesity

(2008) Michael Benzinou et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

Increasing Heritability of BMI and Stronger Associations With the FTO Gene Over Childhood

(2008) Claire M.A. Haworth et al.   Obesity