Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors

Near-Infrared Fluorescence Imaging of Both Colorectal Cancer and Ureters Using a Low-Dose Integrin Targeted Probe

(2014) Floris P. R. Verbeek et al.   ANNALS OF SURGICAL ONCOLOGY

Homogeneous Bispecifics by Disulfide Bridging

(2014) Elizabeth A. Hull et al.   BIOCONJUGATE CHEMISTRY

Anti-CEA Antibody Fragments Labeled with [18F]AlF for PET Imaging of CEA-Expressing Tumors

(2014) S. Lütje et al.   BIOCONJUGATE CHEMISTRY

SPECT- and Fluorescence Image-Guided Surgery Using a Dual-Labeled Carcinoembryonic Antigen-Targeting Antibody

(2014) M. Rijpkema et al.   JOURNAL OF NUCLEAR MEDICINE

Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting

(2013) J P Tiernan et al.   BRITISH JOURNAL OF CANCER

Development of an imaging-guided CEA-pretargeted radionuclide treatment of advanced colorectal cancer: first clinical results

(2013) R Schoffelen et al.   BRITISH JOURNAL OF CANCER

The need for performance standards in clinical translation and adoption of fluorescence molecular imaging

(2013) Eva M. Sevick-Muraca et al.   MEDICAL PHYSICS

Targeted zwitterionic near-infrared fluorophores for improved optical imaging

(2013) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

Image-guided cancer surgery using near-infrared fluorescence

(2013) Alexander L. Vahrmeijer et al.   Nature Reviews Clinical Oncology

Homogeneous antibody fragment conjugation by disulfide bridging introduces ‘spinostics’

(2013) Felix F. Schumacher et al.   Scientific Reports

Drug-Based Optical Agents: Infiltrating Clinics at Lower Risk

(2012) W. Scheuer et al.   Science Translational Medicine

Pretargeted immuno-PET of CEA-expressing intraperitoneal human colonic tumor xenografts: a new sensitive detection method

(2012) Rafke Schoffelen et al.   EJNMMI Research

Synthesis and In Vivo Fate of Zwitterionic Near-Infrared Fluorophores

(2011) Hak Soo Choi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Re-expression of CEACAM1 long cytoplasmic domain isoform is associated with invasion and migration of colorectal cancer

(2011) Junji Ieda et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancer

(2011) Stijn Keereweer et al.   JOURNAL OF SURGICAL ONCOLOGY

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

(2011) Mark D Girgis et al.   EJNMMI Research

Pretargeted radioimmunoscintigraphy in patients with primary colorectal cancer using a bispecific anticarcinoembryonic antigen CEA X anti-di-diethylenetriaminepentaacetic acid F(ab′)2 antibody

(2010) Frits Aarts et al.   CANCER

Single-Dose Intravenous Toxicity Study of IRDye 800CW in Sprague-Dawley Rats

(2010) Milton V. Marshall et al.   MOLECULAR IMAGING AND BIOLOGY

The FLARE™ Intraoperative Near-Infrared Fluorescence Imaging System: A First-in-Human Clinical Trial in Breast Cancer Sentinel Lymph Node Mapping

(2009) Susan L. Troyan et al.   ANNALS OF SURGICAL ONCOLOGY

Nanoparticles functionalised with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells

(2009) Kim L. Vigor et al.   BIOMATERIALS

Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice

(2009) Michael P Kim et al.   Nature Protocols

In Vivo Tumor Targeting and Imaging with Engineered Trivalent Antibody Fragments Containing Collagen-Derived Sequences

(2009) Ángel M. Cuesta et al.   PLoS One

What Is the Role for the Circumferential Margin in the Modern Treatment of Rectal Cancer?

(2008) Iris D. Nagtegaal et al.   JOURNAL OF CLINICAL ONCOLOGY

Imaging in the era of molecular oncology

(2008) Ralph Weissleder et al.   NATURE

In Vivo Near-infrared Fluorescence Imaging of Carcinoembryonic Antigen–expressing Tumor Cells in Mice

(2008) Marcus-René Lisy et al.   RADIOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL