Homogeneous antibody fragment conjugation by disulfide bridging introduces ‘spinostics’

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Molecular Scaffolds Using Multiple Orthogonal Conjugations: Applications in Chemical Biology and Drug Discovery

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In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation

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Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells

(2011) Paul Moody et al.   CHEMBIOCHEM

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis

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X-band rapid-scan EPR of nitroxyl radicals

(2011) Deborah G. Mitchell et al.   JOURNAL OF MAGNETIC RESONANCE

Polymeric Dibromomaleimides As Extremely Efficient Disulfide Bridging Bioconjugation and Pegylation Agents

(2011) Mathew W. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ranking the Susceptibility of Disulfide Bonds in Human IgG1 Antibodies by Reduction, Differential Alkylation, and LC−MS Analysis

(2010) Hongcheng Liu et al.   ANALYTICAL CHEMISTRY

Site-Specific and Stoichiometric Modification of Antibodies by Bacterial Transglutaminase

(2010) Simone Jeger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

(2010) Mark E. B. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted cancer therapies

(2010) Saurabh Aggarwal   NATURE REVIEWS DRUG DISCOVERY

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

Cardiac biomarkers and the case for point-of-care testing

(2009) Barry McDonnell et al.   CLINICAL BIOCHEMISTRY

Kinetics of anti-carcinoembryonic antigen antibody internalization: effects of affinity, bivalency, and stability

(2008) Michael M. Schmidt et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

(2008) Jagath R Junutula et al.   NATURE BIOTECHNOLOGY

Protein therapeutics: a summary and pharmacological classification

(2007) Benjamin Leader et al.   NATURE REVIEWS DRUG DISCOVERY