Increased Lipocalin-2 in the retinal pigment epithelium ofCryba1cKO mice is associated with a chronic inflammatory response

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling

(2014) Mallika Valapala et al.   Autophagy

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

(2013) Kai Kaarniranta et al.   Autophagy

Regulation of mTORC1 and its impact on gene expression at a glance

(2013) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

(2012) M. Suzuki et al.   JOURNAL OF CELL SCIENCE

Animal models of age related macular degeneration

(2012) Mark E. Pennesi et al.   MOLECULAR ASPECTS OF MEDICINE

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

(2012) Maroof Hasan et al.   NATURE IMMUNOLOGY

Mutation in the  A3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat

(2011) J. S. Zigler et al.   JOURNAL OF CELL SCIENCE

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

IntracellularMycobacterium aviumIntersect Transferrin in the Rab11+Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway

(2010) Øyvind Halaas et al.   JOURNAL OF INFECTIOUS DISEASES

CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration

(2010) William Raoul et al.   Journal of Neuroinflammation

Para-inflammation in the aging retina

(2009) Heping Xu et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

βA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development

(2007) Debasish Sinha et al.   MOLECULAR AND CELLULAR NEUROSCIENCE