Advancement in Cascade [1,n]-Hydrogen Transfer/Cyclization: A Method for Direct Functionalization of Inactive C(sp3)H Bonds

Tandem sp3 C–H Functionlization/Decarboxylation of 2-Alkylazaarenes with Coumarin-3-carboxylic Acids

(2014) Lubin Xu et al.   ORGANIC LETTERS

A Branched Domino Reaction: Asymmetric Organocatalytic Two-Component Four-Step Synthesis of Polyfunctionalized Cyclohexene Derivatives

(2013) Xiaofei Zeng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Intramolecular 1,5-Hydride Transfer/Cyclization through the Direct Functionalization of C(sp3)-H Bonds Adjacent to a Heteroatom: From Nitrogen to Oxygen

(2013) Min Wang   ChemCatChem

Enantioselective organocatalytic oxidative enamine catalysis–1,5-hydride transfer–cyclization sequences: asymmetric synthesis of tetrahydroquinolines

(2013) Young Ku Kang et al.   CHEMICAL COMMUNICATIONS

Cascade Hydroamination/Redox Reaction for the Synthesis of Cyclic Aminals Catalyzed by a Combined Gold Complex and Brønsted Acid

(2013) Yu-Ping He et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Redox-Neutral Approach to CH Functionalization

(2013) Bo Peng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Thermal Cyclization of Phenylallenes That Containortho-1,3-Dioxolan-2-yl Groups: New Cascade Reactions Initiated by 1,5-Hydride Shifts of Acetalic H Atoms

(2013) Mateo Alajarin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal-Free α-Amination of Secondary Amines: Computational and Experimental Evidence for Azaquinone Methide and Azomethine Ylide Intermediates

(2013) Arne Dieckmann et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis, Properties, and Structures of Functionalized peri-Xanthenoxanthene

(2013) Na Lv et al.   ORGANIC LETTERS

Facile Access to Ring-Fused Aminals via Direct α-Amination of Secondary Amines with o-Aminobenzaldehydes: Synthesis of Vasicine, Deoxyvasicine, Deoxyvasicinone, Mackinazolinone, and Ruteacarpine

(2013) Daniel Seidel et al.   SYNTHESIS-STUTTGART

Gold-Catalyzed Functionalization of Unactivated C(sp3)H Bonds by Hydride Transfer Facilitated by Alkynylspirocyclopropanes

(2012) José Barluenga et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Free Oxidation/C(sp3)H Functionalization of Unactivated Alkynes Using Pyridine-N-Oxide as the External Oxidant

(2012) Dian-Feng Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Activation in S-Alkenyl Sulfoximines: An Endo 1,5-Hydrogen Migration

(2012) Xuefeng Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intramolecular Redox-Triggered CH Functionalization

(2012) Igor D. Jurberg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Catalyzed Oxidative Cyclizations ofcis-3-En-1-ynes To Form Cyclopentenone Derivatives

(2012) Sabyasachi Bhunia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Direct C sp 3H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers

(2012) Zhi-Wei Jiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic C–H activation reactions

(2012) Subhas Chandra Pan   Beilstein Journal of Organic Chemistry

Oxidative Enamine Catalysis: Direct Catalytic Enantioselective β-Functionalization of Aldehydes

(2012) Jian Xiao   ChemCatChem

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Total Synthesis of Polyene Natural Product Dihydroxerulin by Mild Organocatalyzed Dehydrogenation of Alcohols

(2012) Hexin Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Enantioselective tert-Aminocyclization by Asymmetric Binary Acid Catalysis (ABC): Stereospecific 1,5-Hydrogen Transfer

(2012) Liujuan Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

C–H Bond Functionalization via Hydride Transfer: Formation of α-Arylated Piperidines and 1,2,3,4-Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C–H Bonds

(2012) Paul A. Vadola et al.   JOURNAL OF ORGANIC CHEMISTRY

Zinc(II)-Catalyzed Redox Cross-Dehydrogenative Coupling of Propargylic Amines and Terminal Alkynes for Synthesis of N-Tethered 1,6-Enynes

(2012) Tsuyuka Sugiishi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1,5-(H, RO, RS) shift/6π-electrocyclic ring closure tandem processes on N-[(α-heterosubstituted)-2-tolyl]ketenimines: a case study of relative migratory aptitudes and activating effects

(2012) Mateo Alajarín et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Brønsted Acid Catalyzed sp3 C–H Functionalization

(2012) Rui Niu et al.   ORGANIC LETTERS

FeCl3-Catalyzed Stereoselective Construction of Spirooxindole Tetrahydroquinolines via Tandem 1,5-Hydride Transfer/Ring Closure

(2012) Yan-Yan Han et al.   ORGANIC LETTERS

Concise Route to 3-Arylisoquinoline Skeleton by Lewis Acid Catalyzed C(sp3)–H Bond Functionalization and Its Application to Formal Synthesis of (±)-Tetrahydropalmatine

(2012) Keiji Mori et al.   ORGANIC LETTERS

Functionalization of Acetalic C(sp3)-H Bonds by Scandium(III) Triflate-Catalyzed Intramolecular Redox Reactions: Tandem 1,4-Hydride Transfer/1,5-Cyclization Processes Leading to Protected 1-Indanones

(2011) Mateo Alajarin et al.   ADVANCED SYNTHESIS & CATALYSIS

Oxidative and Enantioselective Cross-Coupling of Aldehydes and Nitromethane Catalyzed by Diphenylprolinol Silyl Ether

(2011) Yujiro Hayashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclization by Catalytic Ruthenium Carbene Insertion into C sp 3H Bonds

(2011) Fermín Cambeiro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold α-Oxo Carbenoids in Catalysis: Catalytic Oxygen-Atom Transfer to Alkynes

(2011) Jian Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 5,6-Spiroethers and Evaluation of their Affinities for the Bacterial A Site

(2011) Ioannis A. Katsoulis et al.   CHEMBIOCHEM

Direct Sp3α-C–H activation and functionalization of alcohol and ether

(2011) Shu-Yu Zhang et al.   CHEMICAL SOCIETY REVIEWS

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

Recent advances in transition metal-catalyzed sp3C–H amination adjacent to double bonds and carbonyl groups

(2011) Thomas A. Ramirez et al.   CHEMICAL SOCIETY REVIEWS

Rapid Access to 3-Aryltetralin Skeleton via C(sp3)–H Bond Functionalization: Investigation on the Substituent Effect of Aromatic Ring Adjacent to C–H Bond in Hydride Shift/Cyclization Sequence

(2011) Keiji Mori et al.   CHEMISTRY LETTERS

Enantioselective Gold-Catalyzed Functionalization of Unreactive sp3 CH Bonds through a Redox-Neutral Domino Reaction

(2011) Guanghua Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tandem 1,5-Hydride Shift/6π Electrocyclization of Ketenimines and Carbodiimides Substituted with Cyclic Acetal and Dithioacetal Functions: Experiments and Computations

(2011) Mateo Alajarin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

[1,5]-Hydride Transfer/Cyclization of ortho-Amino Alkynyl Fischer Carbene Complexes: A Useful Tool for the Synthesis of Quinoline Derivatives

(2011) José Barluenga et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Pd(0)-Catalyzed [1,5]-Sigmatropic Hydrogen Shift of Propargylic Esters toward Substituent Naphthylamines

(2011) Shu-Chun Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Expeditious Construction of a Carbobicyclic Skeleton via sp3-C−H Functionalization: Hydride Shift from an Aliphatic Tertiary Position in an Internal Redox Process

(2011) Keiji Mori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold and Brønsted Acid Catalyzed Hydride Shift onto Allenes: Divergence in Product Selectivity

(2011) Benoit Bolte et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redox-Neutral Indole Annulation Cascades

(2011) Michael C. Haibach et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Gold(I)-Catalyzed Rearrangements of Acetylenic Amine-N-Oxides: Computational Investigations Lead to a New Mechanism Confirmed by Experiment

(2011) Elizabeth L. Noey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Activation of Enantiotopic C(sp3)−Hydrogen by Means of Chiral Phosphoric Acid: Asymmetric Synthesis of Tetrahydroquinoline Derivatives

(2011) Keiji Mori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Synthesis of Aperidine

(2011) Toshiyuki Wakimoto et al.   ORGANIC LETTERS

Highly Enantioselective Synthesis of Tetrahydroquinolines via Cobalt(II)-Catalyzed Tandem 1,5-Hydride Transfer/Cyclization

(2011) Weidi Cao et al.   ORGANIC LETTERS

Enantioselective organocatalytic synthesis of medicinally privileged 2-amino-4H-chromene-3-carbonitriles via a cascade process

(2011) Zhiyun Du et al.   TETRAHEDRON LETTERS

Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions

(2011) Shi-Lei Zhang et al.   Nature Communications

Challenge and progress: palladium-catalyzed sp3 C–H activation

(2011) Hu Li et al.   Catalysis Science & Technology

Platinum-catalyzed 1,3-acyloxy migration/[1,5]-hydride transfer/cycloaddition sequence: synthesis of ring-fused tetrahydroquinolines

(2011) Xiao-Feng Xia et al.   RSC Advances

Concise Synthesis of Tetrahydropyrans by a Tandem Oxa-Michael/Tsuji-Trost Reaction

(2010) Liang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Product-selectivity control by the nature of the catalyst: Lewis acid-catalyzed selective formation of ring-fused tetrahydroquinolines and tetrahydroazepines via intramolecular redox reaction

(2010) Guanghua Zhou et al.   CHEMICAL COMMUNICATIONS

C−H Bond Activations by Metal Oxo Compounds

(2010) Ahmet Gunay et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Hydroalkylation of Alkynyl Ethers via a Gold(I)-Catalyzed 1,5-Hydride Shift/Cyclization Sequence

(2010) Igor Dias Jurberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-Pot Synthesis of 1,3-Disubstituted Allenes from 1-Alkynes, Aldehydes, and Morpholine

(2010) Jinqiang Kuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Organocatalytic C−H Bond Functionalization via Tandem 1,5-Hydride Transfer/Ring Closure: Asymmetric Synthesis of Tetrahydroquinolines

(2010) Young Ku Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Domino reactions initiated by intramolecular hydride transfers from tri(di)arylmethane fragments to ketenimine and carbodiimide functions

(2010) Mateo Alajarin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Expeditious Synthesis of Benzopyrans via Lewis Acid-Catalyzed C−H Functionalization: Remarkable Enhancement of Reactivity by anOrthoSubstituent

(2010) Keiji Mori et al.   ORGANIC LETTERS

Platinum(II)-Catalyzed Intramolecular Cyclization ofo-Substituted Aryl Alkynes through sp3CH Activation

(2009) Shangdong Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dyotropic Reactions: Mechanisms and Synthetic Applications†

(2009) Israel Fernández et al.   CHEMICAL REVIEWS

C−H Bond Activation and Organometallic Intermediates on Isolated Metal Centers on Oxide Surfaces

(2009) Christophe Coperet   CHEMICAL REVIEWS

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Expeditious Construction of Quinazolines via Brønsted Acid-induced C–H Activation: Further Extension of “tert-Amino Effect”

(2009) Keiji Mori et al.   CHEMISTRY LETTERS

Intramolecular Hydro-N-alkylation of Hydrazones and Oxime Ethers: Synthesis of Novel D-Secoestrone Isoquinuclidines via Domino 1,5-Hydride Shift/Cyclization

(2009) Éva Frank et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Scope and Limitations of the T-Reaction Employing Some Functionalized C-H-Acids and Naturally Occurring Secondary Amines

(2009) Constantin Rabong et al.   HETEROCYCLES

Platinum and Ruthenium Chloride-Catalyzed Cycloisomerization of 1-Alkyl-2-ethynylbenzenes: Interception of π-Activated Alkynes with a Benzylic C−H Bond

(2009) Mamoru Tobisu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of (−)-PNU-286607 by Asymmetric Cyclization of Alkylidene Barbiturates

(2009) J. Craig Ruble et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Intramolecular Redox Reactions: Ring-Fused Tetrahydroquinolines

(2009) Sandip Murarka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−H Bond Functionalization via Hydride Transfer: Direct Coupling of Unactivated Alkynes and sp3C−H Bonds Catalyzed by Platinum Tetraiodide

(2009) Paul A. Vadola et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Two-Step, Formal [4 + 2] Approach toward Piperidin-4-ones via Au Catalysis

(2009) Li Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-Catalyzed Isomerization and Intramolecular Redox Reaction of Alkynyl Ethers Affording Dihydropyrans and Ketoolefins

(2009) Daisuke Shikanai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−H Bond Functionalization via Hydride Transfer: Synthesis of Dihydrobenzopyrans fromortho-Vinylaryl Akyl Ethers

(2009) Kevin M. McQuaid et al.   ORGANIC LETTERS

Functionalization of Csp3–H bond—Sc(OTf)3-catalyzed domino 1,5-hydride shift/cyclization/Friedel–Crafts acylation reaction of benzylidene Meldrum’s acids

(2009) Stuart J. Mahoney et al.   TETRAHEDRON LETTERS

[1,5]-Hydride Transfer/Cyclizations on Alkynyl Fischer Carbene Complexes: Synthesis of 1,2-Dihydroquinolinyl Carbene Complexes and Cascade Reactions

(2008) José Barluenga et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Naphthalenyl Acetate by Platinum-Catalyzed [1,5]-Sigmatropic Hydrogen Shift of Propargylic Esters

(2008) Xing-Zhong Shu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Facile Formation of Cyclic Aminals through a Brønsted Acid-Promoted Redox Process

(2008) Chen Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (−)-Serotobenine

(2008) Yasuaki Koizumi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold-Catalyzed 1,3-Addition of a sp3-Hybridized C−H Bond to Alkenylcarbenoid Intermediate

(2008) Sabyasachi Bhunia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−H Bond Functionalization via Hydride Transfer: Lewis Acid Catalyzed Alkylation Reactions by Direct Intramolecular Coupling of sp3C−H Bonds and Reactive Alkenyl Oxocarbenium Intermediates

(2008) Kevin M. McQuaid et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold-Catalyzed Highly Enantioselective Synthesis of Axially Chiral Allenes

(2008) Vanessa Kar-Yan Lo et al.   ORGANIC LETTERS

A Cascade Reaction with Iminium Ion Isomerization as the Key Step Leading to Tetrahydropyrimido[4,5-d]pyrimidines

(2008) Lianyou Zheng et al.   ORGANIC LETTERS

Lewis Acid Catalyzed Formation of Tetrahydroquinolines via an Intramolecular Redox Process

(2008) Sandip Murarka et al.   ORGANIC LETTERS

α-Amination of Nitrogen Heterocycles:  Ring-Fused Aminals

(2007) Chen Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY