4.4 Article

One-pot synthesis of the naturally occurring dimeric carbazole alkaloid murranimbine and its analogue

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 29, Pages 3732-3735

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.05.030

Keywords

Girinimbine; Koenidine; Murranimbine; Dimerization; BF3-etherate

Funding

  1. Council of Scientific and Industrial Research

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Murranimbine, a naturally occurring dimeric carbazole alkaloid, isolated from the root bark of Murraya euchrestfolia was synthesized in one step by the application of Lewis acid (BF3-Et2O) on its monomer girinimbine. A new dimer of koenidine was also synthesized following the same procedure. Structures of these dimeric carbazole alkaloids were determined by detailed spectral analysis. (C) 2010 Elsevier Ltd. All rights reserved.

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