A Multiwell Platform for Studying Stiffness-Dependent Cell Biology

Integration of statistical modeling and high-content microscopy to systematically investigate cell–substrate interactions

(2010) Wen Li Kelly Chen et al.   BIOMATERIALS

Surface Creasing Instability of Soft Polyacrylamide Cell Culture Substrates

(2010) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

(2010) Fei Liu et al.   JOURNAL OF CELL BIOLOGY

How deeply cells feel: methods for thin gels

(2010) Amnon Buxboim et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

(2010) Robert W. Tilghman et al.   PLoS One

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Studying the Effects of Matrix Stiffness on Cellular Function using Acrylamide-based Hydrogels

(2010) Alexandra Cretu et al.   Jove-Journal of Visualized Experiments

Absence of Filamin A Prevents Cells from Responding to Stiffness Gradients on Gels Coated with Collagen but not Fibronectin

(2009) Fitzroy J. Byfield et al.   BIOPHYSICAL JOURNAL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

(2009) Eric A. Klein et al.   CURRENT BIOLOGY

Designing materials to direct stem-cell fate

(2009) Matthias P. Lutolf et al.   NATURE

Differential Matrix Rigidity Response in Breast Cancer Cell Lines Correlates with the Tissue Tropism

(2009) Ana Kostic et al.   PLoS One

Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation

(2008) Andrew S. Rowlands et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE

Creasing instability of surface-attached hydrogels

(2008) Verónica Trujillo et al.   Soft Matter

Bone Marrow-Derived Human Mesenchymal Stem Cells Become Quiescent on Soft Substrates but Remain Responsive to Chemical or Mechanical Stimuli

(2008) Jessamine P. Winer et al.   TISSUE ENGINEERING PART A