The CD1 size problem: lipid antigens, ligands, and scaffolds

Dynamics of the Antigen-binding Grooves in CD1 Proteins

(2013) Diana Garzón et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens

(2013) Dalam Ly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: CD1a Tetramers and Dextramers Identify Human Lipopeptide-Specific T Cells Ex Vivo

(2013) A. G. Kasmar et al.   JOURNAL OF IMMUNOLOGY

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens

(2013) Annemieke de Jong et al.   NATURE IMMUNOLOGY

Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor

(2012) Jacinto López-Sagaseta et al.   EMBO JOURNAL

Diverse antigen presentation by the Group 1 CD1 molecule, CD1c

(2012) Erin J. Adams   MOLECULAR IMMUNOLOGY

Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus

(2012) Federica Facciotti et al.   NATURE IMMUNOLOGY

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

(2012) Onisha Patel et al.   NATURE IMMUNOLOGY

Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens

(2012) Enrico Girardi et al.   NATURE IMMUNOLOGY

Arl13b regulates endocytic recycling traffic

(2012) D. C. Barral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Saposins utilize two strategies for lipid transfer and CD1 antigen presentation

(2012) L. Leon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Basis for Recognition of CD1d/α-Galactosylceramide by a Human Non-Vα24 T Cell Receptor

(2012) Jacinto López-Sagaseta et al.   PLOS BIOLOGY

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

(2011) Thierry Mallevaey et al.   IMMUNITY

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

(2011) Kwok S. Wun et al.   IMMUNITY

Identification of Self-lipids Presented by CD1c and CD1d Proteins

(2011) Neil A. Haig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans

(2011) Anne G. Kasmar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NKT Cell Ligand Recognition Logic: Molecular Basis for a Synaptic Duet and Transmission of Inflammatory Effectors

(2011) S. Joyce et al.   JOURNAL OF IMMUNOLOGY

Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors

(2011) Daniel G Pellicci et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

(2011) Yuki Kinjo et al.   NATURE IMMUNOLOGY

Analysis of the CD1 Antigen Presenting System in Humanized SCID Mice

(2011) Jennifer L. Lockridge et al.   PLoS One

Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system

(2011) S. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

(2011) L. F. Garcia-Alles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

(2011) Luis F. Garcia-Alles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells

(2011) Enrico Girardi et al.   PLOS BIOLOGY

High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells

(2010) Claudia de Lalla et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation

(2010) Louise Scharf et al.   IMMUNITY

Lysosomal α-Galactosidase Controls the Generation of Self Lipid Antigens for Natural Killer T Cells

(2010) Alexandre Darmoise et al.   IMMUNITY

Regulation of CD1 Antigen-presenting Complex Stability

(2010) Artur N. Odyniec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function

(2010) Sebastian Zeissig et al.   JOURNAL OF CLINICAL INVESTIGATION

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

(2010) Yali Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire

(2010) Annemieke de Jong et al.   NATURE IMMUNOLOGY

Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d

(2010) K. Muindi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycolic Acids Constitute a Scaffold for Mycobacterial Lipid Antigens Stimulating CD1-Restricted T Cells

(2009) Emilie Layre et al.   CHEMISTRY & BIOLOGY

Kinetics and Cellular Site of Glycolipid Loading Control the Outcome of Natural Killer T Cell Activation

(2009) Jin S. Im et al.   IMMUNITY

CD1-restricted adaptive immune responses toMycobacteriain human group 1 CD1 transgenic mice

(2009) Kyrie Felio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

(2009) Ildiko Van Rhijn et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Natural Lipid Ligands Associated with Human CD1d Targeted to Different Subcellular Compartments

(2009) W. Yuan et al.   JOURNAL OF IMMUNOLOGY

Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by Vα14 i NKT Cells

(2009) Barbara A. Sullivan et al.   JOURNAL OF IMMUNOLOGY

Early Recycling Compartment Trafficking of CD1a Is Essential for Its Intersection and Presentation of Lipid Antigens

(2009) M. Cernadas et al.   JOURNAL OF IMMUNOLOGY

Determination of Cellular Lipids Bound to Human CD1d Molecules

(2009) Daryl Cox et al.   PLoS One

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

(2009) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism

(2008) M Mahmood Hussain et al.   CURRENT OPINION IN LIPIDOLOGY

Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules

(2008) Arthur Kaser et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

pH-Dependent Interdomain Tethers of CD1b Regulate Its Antigen Capture

(2008) Miguel Relloso et al.   IMMUNITY

CD1a and MHC Class I Follow a Similar Endocytic Recycling Pathway

(2008) Duarte C Barral et al.   TRAFFIC