Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

C9orf72 expansion disrupts ATM-mediated chromosomal break repair

(2017) Callum Walker et al.   NATURE NEUROSCIENCE

Skeletal muscle aging: influence of oxidative stress and physical exercise

(2017) Mariana Janini Gomes et al.   Oncotarget

A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia

(2016) Alice Pannérec et al.   Aging-US

Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia

(2016) Ana Jovičić et al.   JOURNAL OF NEUROCHEMISTRY

Architecture of the symmetric core of the nuclear pore

(2016) D. H. Lin et al.   SCIENCE

Elderly mouse skeletal muscle fibres have a diminished capacity to upregulate NCAM production in response to denervation

(2015) Ashley Gillon et al.   BIOGERONTOLOGY

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

(2015) Ke Zhang et al.   NATURE

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

(2015) Brian D. Freibaum et al.   NATURE

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

(2015) Ana Jovičić et al.   NATURE NEUROSCIENCE

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

(2015) T. Scott Bowen et al.   Journal of Cachexia Sarcopenia and Muscle

Aging related changes in determinants of muscle force generating capacity: A comparison of muscle aging in men and male rodents

(2014) Sam B. Ballak et al.   AGEING RESEARCH REVIEWS

The diverse roles of the Nup93/Nic96 complex proteins – structural scaffolds of the nuclear pore complex with additional cellular functions

(2014) Benjamin Vollmer et al.   BIOLOGICAL CHEMISTRY

Lifelong exercise and locally produced insulin-like growth factor-1 (IGF-1) have a modest influence on reducing age-related muscle wasting in mice

(2014) C. D. McMahon et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Glycosylation of the Nuclear Pore

(2014) Bin Li et al.   TRAFFIC

Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold

(2013) Khanh Huy Bui et al.   CELL

Uncovering Nuclear Pore Complexity with Innovation

(2013) Rebecca L. Adams et al.   CELL

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

Presynaptic to postsynaptic relationships of the neuromuscular junction are held constant across age and muscle fiber type

(2013) Michael R. Deschenes et al.   Developmental Neurobiology

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

(2013) P. P. Shah et al.   GENES & DEVELOPMENT

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

(2012) Sharon L. Rowan et al.   PLoS One

Shared Resistance to Aging and ALS in Neuromuscular Junctions of Specific Muscles

(2012) Gregorio Valdez et al.   PLoS One

Age-related loss of muscle fibres is highly variable amongst mouse skeletal muscles

(2011) Philip W. Sheard et al.   BIOGERONTOLOGY

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

(2010) G. Valdez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Old Nuclei Spring New Leaks

(2009) Chitra V. Kotwaliwale et al.   CELL

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

Flexible Gates: Dynamic Topologies and Functions for FG Nucleoporins in Nucleocytoplasmic Transport

(2009) Laura J. Terry et al.   EUKARYOTIC CELL

Exercise and the brain: something to chew on

(2009) Henriette van Praag   TRENDS IN NEUROSCIENCES

Structure, dynamics and function of nuclear pore complexes

(2008) Maximiliano A. D’Angelo et al.   TRENDS IN CELL BIOLOGY