Evolutionary conservation of the antimicrobial function of mucus: a first defence against infection

Mucin Production and Hydration Responses to Mucopurulent Materials in Normal versus Cystic Fibrosis Airway Epithelia

(2018) Lubna H. Abdullah et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bicarbonate in cystic fibrosis

(2017) Karl Kunzelmann et al.   Journal of Cystic Fibrosis

Adaptive mechanisms and physiological effects of suspended and settled sediment on barrel sponges

(2017) Emily C. McGrath et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Akkermansia muciniphila and its role in regulating host functions

(2017) Muriel Derrien et al.   MICROBIAL PATHOGENESIS

The particle in the spider's web: transport through biological hydrogels

(2017) Jacob Witten et al.   Nanoscale

Extracellular Signals of a Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cell Line Facilitate the Penetration of Pseudomonas aeruginosa PAO1 Strain through the Mucin Layer

(2017) Naoki Hayashi et al.   Frontiers in Cellular and Infection Microbiology

Comparative Genomic Analysis of the Human Gut Microbiome Reveals a Broad Distribution of Metabolic Pathways for the Degradation of Host-Synthetized Mucin Glycans and Utilization of Mucin-Derived Monosaccharides

(2017) Dmitry A. Ravcheev et al.   Frontiers in Genetics

Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments

(2017) Céline Portal et al.   PLoS One

Metabolic responses of a phototrophic sponge to sedimentation supports transitions to sponge-dominated reefs

(2017) Andrew Biggerstaff et al.   Scientific Reports

Biological modeling of mucus to modulate mucus barriers

(2016) Jean-Luc Desseyn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Interaction between Respiratory Pathogens and Mucus

(2016) Mark Zanin et al.   Cell Host & Microbe

Acidic pH increases airway surface liquid viscosity in cystic fibrosis

(2016) Xiao Xiao Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of essential genes of Pseudomonas aeruginosa for its growth in airway mucus

(2016) Mohammed Abd Alrahman et al.   JOURNAL OF MICROBIOLOGY

A Selective Mucin/Methylcellulose Hybrid Gel with Tailored Mechanical Properties

(2016) Constantin Nowald et al.   MACROMOLECULAR BIOSCIENCE

Searching the Evolutionary Origin of Epithelial Mucus Protein Components—Mucins and FCGBP

(2016) Tiange Lang et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Mucus Barrier to Inhaled Gene Therapy

(2016) Gregg A Duncan et al.   MOLECULAR THERAPY

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

(2016) Joakim H. Bergström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coral mucus fuels the sponge loop in warm- and cold-water coral reef ecosystems

(2016) Laura Rix et al.   Scientific Reports

Contribution of Stress Responses to Antibiotic Tolerance in Pseudomonas aeruginosa Biofilms

(2015) Philip S. Stewart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Akkermansia muciniphila Adheres to Enterocytes and Strengthens the Integrity of the Epithelial Cell Layer

(2015) Justus Reunanen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mucins: A biologically relevant glycan barrier in mucosal protection

(2015) Anthony P. Corfield   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The effect of nanoparticle permeation on the bulk rheological properties of mucus from the small intestine

(2015) M.D. Wilcox et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Exploring the role and diversity of mucins in health and disease with special insight into non-communicable diseases

(2015) Santosh Kumar Behera et al.   GLYCOCONJUGATE JOURNAL

Repairing The Broken Market For Antibiotic Innovation

(2015) Kevin Outterson et al.   HEALTH AFFAIRS

The coral core microbiome identifies rare bacterial taxa as ubiquitous endosymbionts

(2015) Tracy D Ainsworth et al.   ISME Journal

Temperature-induced behavioral switches in a bacterial coral pathogen

(2015) Melissa Garren et al.   ISME Journal

Genetic control of bacterial biofilms

(2015) Krystyna I. Wolska et al.   JOURNAL OF APPLIED GENETICS

Bacillus anthracis spores germinate extracellularly at air-liquid interface in an in vitro lung model under serum-free conditions

(2015) J.D. Powell et al.   JOURNAL OF APPLIED MICROBIOLOGY

The Mucus of Actinia equina (Anthozoa, Cnidaria): An Unexplored Resource for Potential Applicative Purposes

(2015) Loredana Stabili et al.   Marine Drugs

Epithelial Sodium Transport and Its Control by Aldosterone: The Story of Our Internal Environment Revisited

(2015) Bernard C. Rossier et al.   PHYSIOLOGICAL REVIEWS

Error, signal, and the placement of Ctenophora sister to all other animals

(2015) Nathan V. Whelan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitrogen cycling in corals: the key to understanding holobiont functioning?

(2015) Nils Rädecker et al.   TRENDS IN MICROBIOLOGY

Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

(2015) Valérie Gouyer et al.   Scientific Reports

Intestinal Colonization Dynamics of Vibrio cholerae

(2015) Salvador Almagro-Moreno et al.   PLoS Pathogens

Modulating Mucin Hydration and Lubrication by Deglycosylation and Polyethylene Glycol Binding

(2015) Thomas Crouzier et al.   Advanced Materials Interfaces

Cystic fibrosis

(2015) Felix Ratjen et al.   Nature Reviews Disease Primers

Pathogenic E. coli Exploits SslE Mucinase Activity to Translocate through the Mucosal Barrier and Get Access to Host Cells

(2015) Maria Valeri et al.   PLoS One

Mucus as a Barrier to Drug Delivery - Understanding and Mimicking the Barrier Properties

(2014) Marie Boegh et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

B cells as a critical node in the microbiota-host immune system network

(2014) Emma Slack et al.   IMMUNOLOGICAL REVIEWS

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide

(2014) B O Schroeder et al.   Mucosal Immunology

Immature truncated O-glycophenotype of cancer directly induces oncogenic features

(2014) Prakash Radhakrishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucins Suppress Virulence Traits of Candida albicans

(2014) Nicole L. Kavanaugh et al.   mBio

SslE Elicits Functional Antibodies That Impair In Vitro Mucinase Activity and In Vivo Colonization by Both Intestinal and Extraintestinal Escherichia coli Strains

(2014) Barbara Nesta et al.   PLoS Pathogens

Paneth Cells: Maestros of the Small Intestinal Crypts

(2013) Hans C. Clevers et al.   Annual Review of Physiology

Tear film mucins: Front line defenders of the ocular surface; comparison with airway and gastrointestinal tract mucins

(2013) Robin R. Hodges et al.   EXPERIMENTAL EYE RESEARCH

Enterotoxigenic Escherichia coli Secretes a Highly Conserved Mucin-Degrading Metalloprotease To Effectively Engage Intestinal Epithelial Cells

(2013) Qingwei Luo et al.   INFECTION AND IMMUNITY

A bacterial pathogen uses dimethylsulfoniopropionate as a cue to target heat-stressed corals

(2013) Melissa Garren et al.   ISME Journal

Life after death: the critical role of extracellular DNA in microbial biofilms

(2013) N.S. Jakubovics et al.   LETTERS IN APPLIED MICROBIOLOGY

Ex Vivo Characterization of Particle Transport in Mucus Secretions Coating Freshly Excised Mucosal Tissues

(2013) Laura M. Ensign et al.   MOLECULAR PHARMACEUTICS

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

(2013) Katharine M. Ng et al.   NATURE

Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing

(2013) D. Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect

(2012) Robert Rauh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mucin Biopolymers Prevent Bacterial Aggregation by Retaining Cells in the Free-Swimming State

(2012) Marina Caldara et al.   CURRENT BIOLOGY

Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype

(2012) Jenny K. Gustafsson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Desulfurization of mucin by Pseudomonas aeruginosa: influence of sulfate in the lungs of cystic fibrosis patients

(2012) C. V. Robinson et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways

(2012) M Kesimer et al.   Mucosal Immunology

Calcium and pH-dependent packing and release of the gel-forming MUC2 mucin

(2012) D. Ambort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

(2012) B. Button et al.   SCIENCE

Mucin Promotes Rapid Surface Motility in Pseudomonas aeruginosa

(2012) A. T. Y. Yeung et al.   mBio

Dynamics of the Tear Film

(2011) Richard J. Braun   Annual Review of Fluid Mechanics

Role of mucus layers in gut infection and inflammation

(2011) Gunnar C Hansson   CURRENT OPINION IN MICROBIOLOGY

Serine Proteases Degrade Airway Mucins in Cystic Fibrosis

(2011) Markus O. Henke et al.   INFECTION AND IMMUNITY

Biology and ecology of coral mucus release

(2011) John C. Bythell et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Mucin dynamics and enteric pathogens

(2011) Michael A. McGuckin et al.   NATURE REVIEWS MICROBIOLOGY

Exopolymer alteration of physical properties of sea ice and implications for ice habitability and biogeochemistry in a warmer Arctic

(2011) Christopher Krembs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of epithelial HCO3− transport in mucin secretion: lessons from cystic fibrosis

(2010) Paul M. Quinton   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A new role for bicarbonate in mucus formation

(2010) Eric Y. T. Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Effect of Polarized Release of CXC-Chemokines from Wild-Type and Cystic Fibrosis Murine Airway Epithelial Cells

(2010) Michelle M. Farberman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MUCUS SECRETION IN FISH-A NOTE*

(2010) Sophie Jakowska   Annals of the New York Academy of Sciences

Coral Mucus: The Properties of Its Constituent Mucins

(2010) Amita A. Jatkar et al.   BIOMACROMOLECULES

Review: Gp-340/DMBT1 in mucosal innate immunity

(2010) Jens Madsen et al.   Innate Immunity

Chemoattraction to Dimethylsulfoniopropionate Throughout the Marine Microbial Food Web

(2010) J. R. Seymour et al.   SCIENCE

Micro- and macrorheology of mucus

(2009) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

Jellyfish mucin may have potential disease-modifying effects on osteoarthritis

(2009) Naoshi Ohta et al.   BMC BIOTECHNOLOGY

Regulation of release of antibacterials from stressed scleractinian corals

(2009) Yuval Geffen et al.   FEMS MICROBIOLOGY LETTERS

Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretion

(2009) Mary Abigail S. Garcia et al.   JOURNAL OF CLINICAL INVESTIGATION

A method for growing a biofilm under low shear at the air–liquid interface using the drip flow biofilm reactor

(2009) Darla M Goeres et al.   Nature Protocols

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

(2009) J. P. Celli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Barrier properties of mucus

(2008) Richard A. Cone   ADVANCED DRUG DELIVERY REVIEWS

Comparison of antimicrobial activity in the epidermal mucus extracts of fish

(2008) Sangeetha Subramanian et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Diversity of microbes associated with the marine sponge, Haliclona simulans, isolated from Irish waters and identification of polyketide synthase genes from the sponge metagenome

(2008) Jonathan Kennedy et al.   ENVIRONMENTAL MICROBIOLOGY

Analysis of mucins: role in laboratory diagnosis

(2008) A S Mall   JOURNAL OF CLINICAL PATHOLOGY

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance to Mucosal Lysozyme Compensates for the Fitness Deficit of Peptidoglycan Modifications by Streptococcus pneumoniae

(2008) Kimberly M. Davis et al.   PLoS Pathogens

Structure, evolution, and biology of the MUC4 mucin

(2007) Pallavi Chaturvedi et al.   FASEB JOURNAL