B cells as a critical node in the microbiota-host immune system network

Cutting Edge: Foxp3+CD4+CD25+ Regulatory T Cells Induced by IL-2 and TGF-  Are Resistant to Th17 Conversion by IL-6

(2014) S. G. Zheng et al.   JOURNAL OF IMMUNOLOGY

Flagellin Induces Antibody Responses through a TLR5- and Inflammasome-Independent Pathway

(2014) A. H. Lopez-Yglesias et al.   JOURNAL OF IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgA deficiency and autoimmunity

(2013) Karmtej Singh et al.   AUTOIMMUNITY REVIEWS

ATG5 regulates plasma cell differentiation

(2013) Kara L. Conway et al.   Autophagy

Glycobiome: Bacteria and mucus at the epithelial interface

(2013) Janneke P. Ouwerkerk et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Innate and Adaptive Immunity Interact to Quench Microbiome Flagellar Motility in the Gut

(2013) Tyler C. Cullender et al.   Cell Host & Microbe

Microbiota-Derived Hydrogen Fuels Salmonella Typhimurium Invasion of the Gut Ecosystem

(2013) Lisa Maier et al.   Cell Host & Microbe

Intraluminal Containment of Commensal Outgrowth in the Gut during Infection-Induced Dysbiosis

(2013) Michael J. Molloy et al.   Cell Host & Microbe

Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit

(2013) Anita Wichmann et al.   Cell Host & Microbe

Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

(2013) Julia Cahenzli et al.   Cell Host & Microbe

The dynamics of gut-associated microbial communities during inflammation

(2013) Sebastian E Winter et al.   EMBO REPORTS

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

(2013) Malin E V Johansson et al.   GUT

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

Clinical Symptoms in Adults with Selective IgA Deficiency: A Case-Control Study

(2013) G. H. Jorgensen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

TLR Activation Excludes Circulating Naive CD8+ T Cells from Gut-Associated Lymphoid Organs in Mice

(2013) S. Heidegger et al.   JOURNAL OF IMMUNOLOGY

The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes

(2013) S Cording et al.   Mucosal Immunology

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis

(2013) Theresa Alenghat et al.   NATURE

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

(2013) Katharine M. Ng et al.   NATURE

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells

(2013) Gretchen E. Diehl et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Plasma cells require autophagy for sustainable immunoglobulin production

(2013) Niccolò Pengo et al.   NATURE IMMUNOLOGY

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

(2013) Keiji Hirota et al.   NATURE IMMUNOLOGY

Resident viruses and their interactions with the immune system

(2013) Breck A Duerkop et al.   NATURE IMMUNOLOGY

Fishing for mammalian paradigms in the teleost immune system

(2013) J Oriol Sunyer   NATURE IMMUNOLOGY

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection

(2013) John R Grainger et al.   NATURE MEDICINE

The gastrointestinal mucus system in health and disease

(2013) Malin E. V. Johansson et al.   Nature Reviews Gastroenterology & Hepatology

Genetic insights into common pathways and complex relationships among immune-mediated diseases

(2013) Miles Parkes et al.   NATURE REVIEWS GENETICS

Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing

(2013) D. Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

(2013) P. C. Kashyap et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Nonredundant Function of Soluble LT 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis

(2013) A. A. Kruglov et al.   SCIENCE

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

(2013) M. Shan et al.   SCIENCE

Stratification and compartmentalisation of immunoglobulin responses to commensal intestinal microbes

(2013) Andrew J. Macpherson et al.   SEMINARS IN IMMUNOLOGY

Use of antibiotics in the treatment of Crohn’s disease

(2013) Maria Lia Scribano   WORLD JOURNAL OF GASTROENTEROLOGY

A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters

(2013) Katerina Hatzi et al.   Cell Reports

Dectin-1 Is Essential for Reverse Transcytosis of Glycosylated SIgA-Antigen Complexes by Intestinal M Cells

(2013) Nicolas Rochereau et al.   PLOS BIOLOGY

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2011

(2012) D E Furst et al.   ANNALS OF THE RHEUMATIC DISEASES

Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut

(2012) Janet Z. Liu et al.   Cell Host & Microbe

The many faces of the clinical picture of common variable immune deficiency

(2012) Elena S. Resnick et al.   Current Opinion in Allergy and Clinical Immunology

Common alleles that influence autophagy and the risk for inflammatory bowel disease

(2012) Agnès Gardet et al.   CURRENT OPINION IN IMMUNOLOGY

A comparative overview of immunoglobulin genes and the generation of their diversity in tetrapods

(2012) Yi Sun et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Novel functions of murine B1 cells: Active phagocytic and microbicidal abilities

(2012) Jixin Gao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Single-cell sequencing provides clues about the host interactions of segmented filamentous bacteria (SFB)

(2012) Sünje J. Pamp et al.   GENOME RESEARCH

B-1 B Cell Development in the Fetus and Adult

(2012) Encarnacion Montecino-Rodriguez et al.   IMMUNITY

Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine

(2012) Cornelia Lindner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice

(2012) Carles Ubeda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Acute Gastrointestinal Infection Induces Long-Lived Microbiota-Specific T Cell Responses

(2012) T. W. Hand et al.   SCIENCE

Lymphoid microenvironments and innate lymphoid cells in the gut

(2012) Claire Pearson et al.   TRENDS IN IMMUNOLOGY

Antigen sampling in the small intestine

(2012) Olga Schulz et al.   TRENDS IN IMMUNOLOGY

Immunogenicity of the pentavalent rotavirus vaccine in African infants

(2012) George E. Armah et al.   VACCINE

The Evolution of Mutualism in Gut Microbiota Via Host Epithelial Selection

(2012) Jonas Schluter et al.   PLOS BIOLOGY

IL-10–Producing Regulatory B10 Cells Inhibit Intestinal Injury in a Mouse Model

(2011) Koichi Yanaba et al.   AMERICAN JOURNAL OF PATHOLOGY

Starvation Compromises Paneth Cells

(2011) Caroline M. Hodin et al.   AMERICAN JOURNAL OF PATHOLOGY

Systems Biology in Immunology: A Computational Modeling Perspective

(2011) Ronald N. Germain et al.   Annual Review of Immunology

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Complete Genome Sequences of Rat and Mouse Segmented Filamentous Bacteria, a Potent Inducer of Th17 Cell Differentiation

(2011) Tulika Prakash et al.   Cell Host & Microbe

The Genome of Th17 Cell-Inducing Segmented Filamentous Bacteria Reveals Extensive Auxotrophy and Adaptations to the Intestinal Environment

(2011) Andrew Sczesnak et al.   Cell Host & Microbe

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

The Lifestyle of the Segmented Filamentous Bacterium: A Non-Culturable Gut-Associated Immunostimulating Microbe Inferred by Whole-Genome Sequencing

(2011) T. Kuwahara et al.   DNA RESEARCH

Biology and novel treatment options for XLA, the most common monogenetic immunodeficiency in man

(2011) Rudi W Hendriks et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8

(2011) John J. Worthington et al.   GASTROENTEROLOGY

The human gut virome: Inter-individual variation and dynamic response to diet

(2011) S. Minot et al.   GENOME RESEARCH

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88

(2011) Erik Larsson et al.   GUT

Prominent Role for Plasmacytoid Dendritic Cells in Mucosal T Cell-Independent IgA Induction

(2011) Hiroyuki Tezuka et al.   IMMUNITY

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

(2011) Markus B. Geuking et al.   IMMUNITY

Commensal and Probiotic Bacteria Influence Intestinal Barrier Function and Susceptibility to Colitis in Nod1−/−;Nod2−/− Mice

(2011) Jane M.M. Natividad et al.   INFLAMMATORY BOWEL DISEASES

Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein

(2011) Eitan M. Akirav et al.   JOURNAL OF NEUROIMMUNOLOGY

European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease

(2011) S. Husby et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut

(2011) Jörg H. Fritz et al.   NATURE

Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans

(2011) B. D. Muegge et al.   SCIENCE

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease

(2011) A. Kathrani et al.   TISSUE ANTIGENS

Systems vaccinology

(2011) Helder I. Nakaya et al.   Current Opinion in HIV and AIDS

Diversity and Genomes of Uncultured Microbial Symbionts in the Termite Gut

(2010) Yuichi HONGOH   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

Mechanisms controlling pathogen colonization of the gut

(2010) Bärbel Stecher et al.   CURRENT OPINION IN MICROBIOLOGY

The Sensing of Environmental Stimuli by Follicular Dendritic Cells Promotes Immunoglobulin A Generation in the Gut

(2010) Keiichiro Suzuki et al.   IMMUNITY

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells

(2010) Matthias Lochner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An externally modulated, noise-driven switch for the regulation of SPI1 in Salmonella enterica serovar Typhimurium

(2010) Marc Bailly-Bechet et al.   JOURNAL OF MATHEMATICAL BIOLOGY

IgT, a primitive immunoglobulin class specialized in mucosal immunity

(2010) Yong-An Zhang et al.   NATURE IMMUNOLOGY

Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis

(2010) T. Obata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

(2010) S. Hapfelmeier et al.   SCIENCE

Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System?

(2010) Y. K. Lee et al.   SCIENCE

Like Will to Like: Abundances of Closely Related Species Can Predict Susceptibility to Intestinal Colonization by Pathogenic and Commensal Bacteria

(2010) Bärbel Stecher et al.   PLoS Pathogens

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

(2010) Kathrin Endt et al.   PLoS Pathogens

Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

(2009) Andrew L. Goodman et al.   Cell Host & Microbe

The role of neutrophils in the event of intestinal inflammation

(2009) Karen L Mumy et al.   CURRENT OPINION IN PHARMACOLOGY

Rotaviruses: From Pathogenesis to Vaccination

(2009) Harry B. Greenberg et al.   GASTROENTEROLOGY

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Primary immunodeficiencies

(2009) Luigi D. Notarangelo   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innate Immunity Mediated by MyD88 Signal Is Not Essential for Induction of Lipopolysaccharide-Specific B Cell Responses but Is Indispensable for Protection against Salmonella enterica serovar Typhimurium infection

(2009) H.-J. Ko et al.   JOURNAL OF IMMUNOLOGY

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota

(2009) Y. Cong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

(2009) E. Slack et al.   SCIENCE

Common variable immunodeficiency disorders: division into distinct clinical phenotypes

(2008) H. Chapel et al.   BLOOD

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Pediatric Selective IgM Immunodeficiency

(2008) Marc F. Goldstein et al.   Clinical & Developmental Immunology

Effect of intestinal microbiota on the induction of regulatory CD25CD4T cells

(2008) H. Ishikawa et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

DC activated via dectin-1 convert Treg into IL-17 producers

(2008) Fabiola Osorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin ΔinvG S. Typhimurium colitis

(2008) Siegfried Hapfelmeier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Worlds within worlds: evolution of the vertebrate gut microbiota

(2008) Ruth E. Ley et al.   NATURE REVIEWS MICROBIOLOGY

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of Mammals and Their Gut Microbes

(2008) R. E. Ley et al.   SCIENCE

Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation

(2008) Caitlin O'Mahony et al.   PLoS Pathogens