Article
Nutrition & Dietetics
Valeria Dipasquale, Katia Lecoeur, Madeleine Aumar, Dominique Guimber, Stephanie Coopman, Audrey Nicolas, Audrey Lecoufle, Audrey Van Malleghem, Dominique Turck, Delphine Ley, Frederic Gottrand
Summary: This study examined the tube-weaning practice of a group of pediatric gastroenterologists managing children receiving prolonged enteral nutrition. The results showed significant practice variation, with most respondents using individualized weaning programs and preferring home-based weaning attempts. The study highlights the need for standardized tube-weaning programs based on increased knowledge about different weaning modalities.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Pediatrics
Aurelie Pham, Emmanuelle Ecochard-Dugelay, Arnaud Bonnard, Enora Le Roux, Thomas Gelas, Veronique Rousseau, Nadege Thomassin, Isabelle Cabon-Boudard, Audrey Nicolas, Audrey Guinot, Julie Rebeuh, Aurelie Le Mandat, Djamal-Dine Djeddi, Virginie Fouquet, Aurelie Boucharny, Sabine Irtan, Julie Lemale, Aurelie Comte, Laure Bridoux-Henno, Claire Dupont-Lucas, Georges Dimitrov, Anne Turquet, Corinne Borderon, Cecile Pelatan, Emilie Chaillou Legault, Camille Jung, Stephanie Willot, Louise Montalva, Delphine Mitanchez, Frederic Gottrand, Marc Bellaiche
Summary: Feeding disorders are common in children with oesophageal atresia, with no typical profile of patients at risk. A national cohort study in France found 42% of children experienced feeding disorders, and systematic screening for these disorders is recommended to improve patient care and outcomes.
ARCHIVES OF DISEASE IN CHILDHOOD
(2022)
Article
Food Science & Technology
Ratih W. Wisnuwardani, Stefaan De Henauw, Maria Forsner, Frederic Gottrand, Inge Huybrechts, Antonios G. Kafatos, Mathilde Kersting, Viktoria Knaze, Yannis Manios, Esther Nova, Denes Molnar, Joseph A. Rothwell, Augustin Scalbert, Stefania Sette, Kurt Widhalm, Luis A. Moreno, Nathalie Michels
Summary: European adolescents had low dietary polyphenol intake, and there was no linear association between dietary polyphenols and serum total antioxidant capacity. Future studies should use polyphenol biomarkers and additional antioxidant measures to confirm these findings.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
S. M. Flieh, M. L. Miguel-Berges, I Huybrechts, M. J. Castillo, M. Gonzalez-Gross, A. Marcos, F. Gottrand, C. Le Donne, K. Widhalm, D. Molnar, P. Stehle, A. Kafatos, J. Dallongeville, E. Gesteiro, S. Abbeddou, L. A. Moreno, E. M. Gonzalez-Gil
Summary: The study found associations between larger portion sizes of vegetables and dairy products with higher VO2 max, while larger portion sizes of margarines and vegetable oils were associated with lower VO2 max. Additionally, larger portion sizes of certain food groups were linked to higher metabolic risk scores.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Nutrition & Dietetics
Jules Morcel, Laurent Beghin, Nathalie Michels, Jeremy Vanhelst, Julien Labreuche, Elodie Drumez, Angela Polito, Marika Ferrari, Laura Censi, Dominique Deplanque, Maria Luisa Miguel-Berges, Thais De Ruyter, Stefaan De Henauw, Luis A. Moreno, Frederic Gottrand
Summary: Cardiovascular diseases are the leading cause of death worldwide. The BELINDA study aims to evaluate cardiovascular risk and its association with risk factors during adolescence. By following up on the HELENA study, this research collects comprehensive clinical and biological data, and identifies differences in BMI and maternal education level among the participating population.
Article
Medicine, General & Internal
Marion Almes, Anne Spraul, Mathias Ruiz, Muriel Girard, Bertrand Roquelaure, Nolwenn Laborde, Frederic Gottrand, Anne Turquet, Thierry Lamireau, Alain Dabadie, Marjorie Bonneton, Alice Thebaut, Babara Rohmer, Florence Lacaille, Pierre Broue, Alexandre Fabre, Karine Mention-Mulliez, Jerome Bouligand, Emmanuel Jacquemin, Emmanuel Gonzales
Summary: This study evaluated the use of NGS in pediatric cholestasis and found that it provided a certain diagnosis in 28.1% of the included patients. However, further investigation is needed to determine the impact of variants, especially in patients with variants of uncertain significance.
Article
Pediatrics
Agate Bourg, Frederic Gottrand, Benoit Parmentier, Julie Thomas, Anne Lehn, Christian Piolat, Arnaud Bonnard, Rony Sfeir, Julie Lienard, Veronique Rousseau, Myriam Pouzac, Agnes Liard, Philippe Buisson, Aurore Haffreingue, Louis David, Sophie Branchereau, Veronique Carcauzon, Nicolas Kalfa, Marc -David Leclair, Hubert Lardy, Sabine Irtan, Francois Varlet, Thomas Gelas, Diana Potop, Marie Auger-Hunault
Summary: This study evaluated the outcomes of long gap esophageal atresia (EA) compared to non-long gap EA/tracheo-esophageal fistula (TEF) at the ages of 1 and 6 years. The study also assessed whether the initial treatment (delayed primary anastomosis of native esophagus vs. esophageal replacement) influenced mortality and morbidity at these ages. The results showed that the long gap EA group had more complications and longer hospital stay at age 1 year, and digestive complications were more frequent in the long gap group at age 6 years. The study concluded that long gap strongly influenced digestive morbidity at age 6 years.
JOURNAL OF PEDIATRIC SURGERY
(2023)
Article
Nutrition & Dietetics
Ivie Maneschy, Luis A. Moreno, Azahara Ruperez, Andrea Jimeno, Maria L. Miguel-Berges, Kurt Widhalm, Anthony Kafatos, Cristina Molina-Hidalgo, Denes Molnar, Frederic Gottrand, Cinzia Le Donne, Yannis Manios, Evangelia Grammatikaki, Marcela Gonzalez-Gross, Mathilde Kersting, Jean Dallongeville, Sonia Gomez-Martinez, Stefaan De Henauw, Alba M. Santaliestra-Pasias
Summary: This study aims to assess eating behavior and its associations with food intake in European adolescents. The results suggest that specific features of eating behavior are related to food intake, particularly in relation to hunger, interest in eating, and emotional eating.
Article
Multidisciplinary Sciences
Guillaume Lacroix, Valerie Gouyer, Mylene Rocher, Frederic Gottrand, Jean-Luc Desseyn
Summary: This study reveals that Muc5b plays a crucial role in maintaining the barrier function of the cervical mucus plug and preventing uterine infections during gestation.
Review
Nutrition & Dietetics
Valeria Dipasquale, Madeleine Aumar, Delphine Ley, Matthieu Antoine, Claudio Romano, Frederic Gottrand
Summary: This review aims to report on the latest hot topics and new directions in tube-feeding strategies for children with neurological disability.
Article
Endocrinology & Metabolism
Katerina Kondakis, Evangelia Grammatikaki, Marios Kondakis, Denes Molnar, Sonia Gomez-Martinez, Marcela Gonzalez-Gross, Anthony Kafatos, Yannis Manios, David Jimenez Pavon, Frederic Gottrand, Laurent Beghin, Mathilde Kersting, Manuel J. Castillo, Luis A. Moreno, Stefaan De Henauw
Summary: This study developed and validated an easy-to-use screening tool for identifying adolescents at high-risk for insulin resistance. By analyzing multiple factors, the study identified indicators associated with high insulin resistance and developed a corresponding scoring index. The ROC analysis in the validation stage showed that the scoring index could effectively identify high-risk insulin resistance patients.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
(2022)
Article
Nutrition & Dietetics
Lucie Marousez, Lea Chantal Tran, Edwina Micours, Matthieu Antoine, Frederic Gottrand, Jean Lesage, Delphine Ley
Summary: Inadequate perinatal nutrition can affect the maturity of the intestinal barrier and the development of the intestinal microbiota in mice. Supplementing with prebiotic fiber appears to improve gut microbiota establishment in postnatal-growth-restricted mice and can lead to changes in intestinal morphology and microbial composition.
Review
Gastroenterology & Hepatology
Paolo Lionetti, Eytan Wine, Rinat Ran Ressler, Gerard J. Minor, Giles Major, Boutaina Zemrani, Frederic Gottrand, Claudio Romano
Summary: Children who require enteral nutrition often experience gastrointestinal symptoms. Fiber-containing enteral formulas can improve bowel function, promote healthy gut microbiota growth, and improve immune homeostasis. However, there is a lack of guidance in clinical practice.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Miguel Seral-Cortes, Sergio Sabroso-Lasa, Marcela Gonzalez-Gross, Carlos Quesada-Gonzalez, Peter Stehle, Frederic Gottrand, Ascension Marcos, Ligia Esperanza-Diaz, Yannis Manios, Odysseas Androutsos, Kurt Widhalm, Denes Molnar, Inge Huybrechts, Manon Muntaner, Aline Meirhaeghe, Diego R. Salazar-Tortosa, Jonatan Ruiz, Luis Mariano Esteban, Idoia A. Labayen, Luis Moreno, HELENA Study Grp
Summary: The study aimed to develop an ALT-specific genetic risk score to evaluate hepatic damage risk in European adolescents. The unweighted and weighted genetic risk scores were found to be significantly associated with ALT levels, and the predictive ability was further improved by integrating BMI as a clinical factor.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Multidisciplinary Sciences
Florine Ruthmann, Nadia Guerouaou, Francis Vasseur, Maria-Claire Migaud, Dominique Deplanque, Frederic Gottrand, Laurent Beghin, Odile Viltart
Summary: Recent studies have found associations between emotional disorders, cognitive impairments, and cardiovascular disorders at the subclinical level. This exploratory study aimed to investigate these relationships in the general population. The results suggest that anxiety and depression are differentially related to cognitive and endothelial functions, but the relationship between cognitive performance and endothelial function was not significant.