An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen Aspergillus fumigatus

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

(2016) Tonia Akoumianaki et al.   Cell Host & Microbe

Putative methyltransferase LaeA and transcription factor CreA are necessary for proper asexual development and controlling secondary metabolic gene cluster expression

(2016) Xiujun Zhang et al.   FUNGAL GENETICS AND BIOLOGY

TrpE feedback mutants reveal roadblocks and conduits toward increasing secondary metabolism in Aspergillus fumigatus

(2016) Pin-Mei Wang et al.   FUNGAL GENETICS AND BIOLOGY

Developmental regulators in Aspergillus fumigatus

(2016) Hee-Soo Park et al.   JOURNAL OF MICROBIOLOGY

Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger

(2016) Lara Manzanares-Miralles et al.   Journal of Proteomics

Secondary metabolite arsenal of an opportunistic pathogenic fungus

(2016) Elaine Bignell et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Regulation of Secondary Metabolism by the Velvet Complex Is Temperature-Responsive in Aspergillus

(2016) Abigail L. Lind et al.   G3-Genes Genomes Genetics

Proteomic analyses reveal the key roles of BrlA and AbaA in biogenesis of gliotoxin in Aspergillus fumigatus

(2015) Kwang-Soo Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters inAspergillus fumigatus

(2015) Kurt Throckmorton et al.   ENVIRONMENTAL MICROBIOLOGY

Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus

(2015) Rebecca A. Owens et al.   EUKARYOTIC CELL

PdbrlA, PdabaA and PdwetA control distinct stages of conidiogenesis in Penicillium digitatum

(2015) Mingshuang Wang et al.   RESEARCH IN MICROBIOLOGY

Mutant characterization andin vivoconditional repression identify aromatic amino acid biosynthesis to be essential forAspergillus fumigatusvirulence

(2015) Anna Sasse et al.   Virulence

Examining the Evolution of the Regulatory Circuit Controlling Secondary Metabolism and Development in the Fungal Genus Aspergillus

(2015) Abigail L. Lind et al.   PLoS Genetics

Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals

(2015) Markus Gressler et al.   eLife

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Co-ordination between BrlA regulation and secretion of the oxidoreductase FmqD directs selective accumulation of fumiquinazoline C to conidial tissues inAspergillus fumigatus

(2014) Fang Yun Lim et al.   CELLULAR MICROBIOLOGY

Identification of Hypoxia-Inducible Target Genes of Aspergillus fumigatus by Transcriptome Analysis Reveals Cellular Respiration as an Important Contributor to Hypoxic Survival

(2014) Kristin Kroll et al.   EUKARYOTIC CELL

Regulatory mutations affecting sulfur metabolism induce environmental stress response in Aspergillus nidulans

(2014) Marzena Sieńko et al.   FUNGAL GENETICS AND BIOLOGY

Two C4-sterol methyl oxidases (Erg25) catalyse ergosterol intermediate demethylation and impact environmental stress adaptation in Aspergillus fumigatus

(2014) S. J. Blosser et al.   MICROBIOLOGY-SGM

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

(2014) Dawoon Chung et al.   PLoS Pathogens

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

(2014) Philipp Wiemann et al.   Frontiers in Microbiology

Penicillium decumbens BrlA extensively regulates secondary metabolism and functionally associates with the expression of cellulase genes

(2013) Yuqi Qin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Point Mutation inftmDBlocks the Fumitremorgin Biosynthetic Pathway inAspergillus fumigatusStrain Af293

(2013) Naoki KATO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae

(2013) Diane O Inglis et al.   BMC MICROBIOLOGY

Functional Analyses of Trichoderma reesei LAE1 Reveal Conserved and Contrasting Roles of This Regulator

(2013) Razieh Karimi-Aghcheh et al.   G3-Genes Genomes Genetics

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

(2013) Erwin Berthier et al.   PLoS Pathogens

Regulation of Sulphur Assimilation Is Essential for Virulence and Affects Iron Homeostasis of the Human-Pathogenic Mould Aspergillus fumigatus

(2013) Jorge Amich et al.   PLoS Pathogens

Ergosterol biosynthesis in Aspergillus fumigatus: its relevance as an antifungal target and role in antifungal drug resistance

(2013) Laura Alcazar-Fuoli et al.   Frontiers in Microbiology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

Trypacidin, a Spore-Borne Toxin from Aspergillus fumigatus, Is Cytotoxic to Lung Cells

(2012) Thierry Gauthier et al.   PLoS One

SREBP-Dependent Triazole Susceptibility in Aspergillus fumigatus Is Mediated through Direct Transcriptional Regulation oferg11A(cyp51A)

(2011) Sara J. Blosser et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Aspergillus Genome Database (AspGD): recent developments in comprehensive multispecies curation, comparative genomics and community resources

(2011) M. B. Arnaud et al.   NUCLEIC ACIDS RESEARCH

Regulation of Development inAspergillus nidulansandAspergillus fumigatus

(2011) Jae-Hyuk Yu   MYCOBIOLOGY

Metabolomic Analysis and Visualization Engine for LC−MS Data

(2010) Eugene Melamud et al.   ANALYTICAL CHEMISTRY

Among Developmental Regulators, StuA but Not BrlA Is Essential for Penicillin V Production inPenicillium chrysogenum

(2010) Claudia Sigl et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

AbaA and WetA govern distinct stages of Aspergillus fumigatus development

(2010) L. Tao et al.   MICROBIOLOGY-SGM

Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans

(2010) Yazmid Reyes-Dominguez et al.   MOLECULAR MICROBIOLOGY

The Aspergillus Genome Database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community

(2009) Martha B. Arnaud et al.   NUCLEIC ACIDS RESEARCH

H3K9 Methylation Regulates Growth and Development inAspergillus fumigatus

(2008) Jonathan M. Palmer et al.   EUKARYOTIC CELL

Transcriptional Profiling Identifies a Role for BrlA in the Response to Nitrogen Depletion and for StuA in the Regulation of Secondary Metabolite Clusters inAspergillus fumigatus

(2008) Kwame Twumasi-Boateng et al.   EUKARYOTIC CELL

Metabolomics ofAspergillus fumigatus

(2008) Jens C. Frisvad et al.   MEDICAL MYCOLOGY

VelB/VeA/LaeA Complex Coordinates Light Signal with Fungal Development and Secondary Metabolism

(2008) O. Bayram et al.   SCIENCE

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens