Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae

(2014) Benjamin P. Knox et al.   EUKARYOTIC CELL

The complex interplay of iron, biofilm formation, and mucoidy affecting antimicrobial resistance ofPseudomonas aeruginosa

(2014) Amanda G. Oglesby-Sherrouse et al.   Pathogens and Disease

Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae

(2013) Diane O Inglis et al.   BMC MICROBIOLOGY

Iron sensing and regulation in Saccharomyces cerevisiae: Ironing out the mechanistic details

(2013) Caryn E Outten et al.   CURRENT OPINION IN MICROBIOLOGY

A Nonribosomal Peptide Synthetase-Derived Iron(III) Complex from the Pathogenic Fungus Aspergillus fumigatus

(2013) Wen-Bing Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Sensing Role of the Glutamine Synthetase in the Nitrogen Regulation Network in Fusarium fujikuroi

(2013) Dominik Wagner et al.   PLoS One

Prototype of an intertwined secondary-metabolite supercluster

(2013) P. Wiemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

(2013) Erwin Berthier et al.   PLoS Pathogens

Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporum

(2013) Sixto M. Leal et al.   PLoS Pathogens

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

(2013) Thorsten Heinekamp et al.   Frontiers in Microbiology

Epidithiol Formation by an Unprecedented Twin Carbon-Sulfur Lyase in the Gliotoxin Pathway

(2012) Daniel H. Scharf et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonribosomal Peptide Synthetase GenespesLandpes1Are Essential for Fumigaclavine C Production in Aspergillus fumigatus

(2012) Karen A. O'Hanlon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis

(2012) Lorna Gallagher et al.   EUKARYOTIC CELL

Gliotoxin effects on fungal growth: Mechanisms and exploitation

(2012) Stephen Carberry et al.   FUNGAL GENETICS AND BIOLOGY

The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus

(2012) Fabio Gsaller et al.   Metallomics

Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae

(2012) C. Wallwey et al.   MICROBIOLOGY-SGM

The velvet complex governs mycotoxin production and virulence ofFusarium oxysporumon plant and mammalian hosts

(2012) Manuel S. López-Berges et al.   MOLECULAR MICROBIOLOGY

Chemotypic and genotypic diversity in the ergot alkaloid pathway of Aspergillus fumigatus

(2012) S. L. Robinson et al.   MYCOLOGIA

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

The Sfp-Type 4′-Phosphopantetheinyl Transferase Ppt1 of Fusarium fujikuroi Controls Development, Secondary Metabolism and Pathogenicity

(2012) Philipp Wiemann et al.   PLoS One

Iron – A Key Nexus in the Virulence of Aspergillus fumigatus

(2012) Hubertus Haas   Frontiers in Microbiology

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

(2011) Daniel H. Scharf et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus

(2011) Carol Davis et al.   CHEMISTRY & BIOLOGY

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

(2011) Markus Schrettl et al.   CURRENT OPINION IN MICROBIOLOGY

SRE1 Regulates Iron-Dependent and -Independent Pathways in the Fungal Pathogen Histoplasma capsulatum

(2011) Lena H. Hwang et al.   EUKARYOTIC CELL

The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation

(2011) Michael Blatzer et al.   FUNGAL GENETICS AND BIOLOGY

Identification of Cryptic Products of the Gliotoxin Gene Cluster Using NMR-Based Comparative Metabolomics and a Model for Gliotoxin Biosynthesis

(2011) Ry R. Forseth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

(2011) Michael Blatzer et al.   PLoS Genetics

Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

(2010) James H Bullard et al.   BMC BIOINFORMATICS

SMURF: Genomic mapping of fungal secondary metabolite clusters

(2010) Nora Khaldi et al.   FUNGAL GENETICS AND BIOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3

(2010) Christiane Wallwey et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin

(2010) Markus Schrettl et al.   PLoS Pathogens

SREB, a GATA Transcription Factor That Directs Disparate Fates in Blastomyces dermatitidis Including Morphogenesis and Siderophore Biosynthesis

(2010) Gregory M. Gauthier et al.   PLoS Pathogens

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

(2010) Markus Schrettl et al.   PLoS Pathogens

Cloud-scale RNA-sequencing differential expression analysis with Myrna

(2010) Ben Langmead et al.   GENOME BIOLOGY

Ferricrocin, a Siderophore Involved in Intra- and Transcellular Iron Distribution in Aspergillus fumigatus

(2009) A. Wallner et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Identification of Cytochrome P450s Required for Fumitremorgin Biosynthesis inAspergillus fumigatus

(2009) Naoki Kato et al.   CHEMBIOCHEM

Iron in innate immunity: starve the invaders

(2009) Tomas Ganz   CURRENT OPINION IN IMMUNOLOGY

The interplay between iron and zinc metabolism in Aspergillus fumigatus

(2009) Sabiha Yasmin et al.   FUNGAL GENETICS AND BIOLOGY

Biosynthesis of the red pigment bikaverin inFusarium fujikuroi: genes, their function and regulation

(2009) Philipp Wiemann et al.   MOLECULAR MICROBIOLOGY

FtmOx1, a non-heme Fe(ii) and α-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus

(2009) Nicola Steffan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Iron-Based Redox Switches in Biology

(2008) F. Wayne Outten et al.   ANTIOXIDANTS & REDOX SIGNALING

FtmPT2, anN-Prenyltransferase fromAspergillus fumigatus, Catalyses the Last Step in the Biosynthesis of Fumitremorgin B

(2008) Alexander Grundmann et al.   CHEMBIOCHEM

H3K9 Methylation Regulates Growth and Development inAspergillus fumigatus

(2008) Jonathan M. Palmer et al.   EUKARYOTIC CELL

Metabolomics ofAspergillus fumigatus

(2008) Jens C. Frisvad et al.   MEDICAL MYCOLOGY

SreA-mediated iron regulation in Aspergillus fumigatus

(2008) Markus Schrettl et al.   MOLECULAR MICROBIOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils

(2008) Janyce A. Sugui et al.   PLoS One

Histoplasma Requires SID1, a Member of an Iron-Regulated Siderophore Gene Cluster, for Host Colonization

(2008) Lena H. Hwang et al.   PLoS Pathogens

SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans

(2003) Harald Oberegger et al.   MOLECULAR MICROBIOLOGY