Secondary metabolite arsenal of an opportunistic pathogenic fungus

De novo genome assembly and annotation of rice sheath rot fungus Sarocladium oryzae reveals genes involved in Helvolic acid and Cerulenin biosynthesis pathways

(2016) Shailaja Hittalmani et al.   BMC GENOMICS

In Vitro Antitrypanosomal Activity of the Secondary Metabolites from the Mutant Strain IU-3 of the Insect Pathogenic Fungus Ophiocordyceps coccidiicola NBRC 100683

(2016) Momoko Ganaha et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Methionine AminoPeptidase Type-2 Inhibitors Targeting Angiogenesis

(2016) Tedman Ehlers et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus

(2016) Joshua A Baccile et al.   Nature Chemical Biology

Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2)

(2016) Yang Zhan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus

(2015) Derek J. Mattern et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

RNA-seq analysis reveals genetic response and tolerance mechanisms to ozone exposure in soybean

(2015) Adam Whaley et al.   BMC GENOMICS

Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters inAspergillus fumigatus

(2015) Kurt Throckmorton et al.   ENVIRONMENTAL MICROBIOLOGY

The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici

(2015) Xiuna Wang et al.   FUNGAL GENETICS AND BIOLOGY

Oxidative stress induces the biosynthesis of citrinin by Penicillium verrucosum at the expense of ochratoxin

(2015) Markus Schmidt-Heydt et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Translating biosynthetic gene clusters into fungal armor and weaponry

(2015) Nancy P Keller   Nature Chemical Biology

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Resistance is not futile: gliotoxin biosynthesis, functionality and utility

(2015) Stephen K. Dolan et al.   TRENDS IN MICROBIOLOGY

Evolution of Chemical Diversity in a Group of Non-Reduced Polyketide Gene Clusters: Using Phylogenetics to Inform the Search for Novel Fungal Natural Products

(2015) Kurt Throckmorton et al.   Toxins

Aflatoxin Biosynthesis Is a Novel Source of Reactive Oxygen Species—A Potential Redox Signal to Initiate Resistance to Oxidative Stress?

(2015) Ludmila Roze et al.   Toxins

Motif-independent de novo detection of secondary metabolite gene clusters—toward identification from filamentous fungi

(2015) Myco Umemura et al.   Frontiers in Microbiology

Immunochemical analysis of fumigaclavine mycotoxins in respiratory tissues and in blood serum of birds with confirmed aspergillosis

(2015) Hadri Latif et al.   Mycotoxin Research

Characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster fromPenicillium coprobium

(2014) Jie Hu et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Co-ordination between BrlA regulation and secretion of the oxidoreductase FmqD directs selective accumulation of fumiquinazoline C to conidial tissues inAspergillus fumigatus

(2014) Fang Yun Lim et al.   CELLULAR MICROBIOLOGY

Biological roles of fungal carotenoids

(2014) Javier Avalos et al.   CURRENT GENETICS

Surface Structure Characterization of Aspergillus fumigatus Conidia Mutated in the Melanin Synthesis Pathway and Their Human Cellular Immune Response

(2014) Jagadeesh Bayry et al.   INFECTION AND IMMUNITY

Fumagillin: An Overview of Recent Scientific Advances and Their Significance for Apiculture

(2014) Johan P. van den Heever et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant Activity and Mechanisms of Action of Natural Compounds Isolated from Lichens: A Systematic Review

(2014) Pollyanna White et al.   MOLECULES

A Non-Canonical NRPS Is Involved in the Synthesis of Fungisporin and Related Hydrophobic Cyclic Tetrapeptides in Penicillium chrysogenum

(2014) Hazrat Ali et al.   PLoS One

Activation of Innate Immune-Response Genes in Little Brown Bats (Myotis lucifugus) Infected with the Fungus Pseudogymnoascus destructans

(2014) Noreen Rapin et al.   PLoS One

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

(2014) Philipp Wiemann et al.   Frontiers in Microbiology

Aspergillus fumigatus SidJ Mediates Intracellular Siderophore Hydrolysis

(2013) Mario Gründlinger et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Point Mutation inftmDBlocks the Fumitremorgin Biosynthetic Pathway inAspergillus fumigatusStrain Af293

(2013) Naoki KATO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae

(2013) Diane O Inglis et al.   BMC MICROBIOLOGY

The use ofFusariumsecondary metabolite biosynthetic genes in chemotypic and phylogenetic studies

(2013) Łukasz Stępień   CRITICAL REVIEWS IN MICROBIOLOGY

Transcriptomic Insights into the Oxidative Response of Stress-Exposed Aspergillus fumigatus

(2013) Emilie Frealle et al.   CURRENT PHARMACEUTICAL DESIGN

Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans

(2013) Junko Yaegashi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

A Nonribosomal Peptide Synthetase-Derived Iron(III) Complex from the Pathogenic Fungus Aspergillus fumigatus

(2013) Wen-Bing Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fumigaclavine C from a Marine-Derived Fungus Aspergillus Fumigatus Induces Apoptosis in MCF-7 Breast Cancer Cells

(2013) Yong-Xin Li et al.   Marine Drugs

Detecting Sequence Homology at the Gene Cluster Level with MultiGeneBlast

(2013) Marnix H. Medema et al.   MOLECULAR BIOLOGY AND EVOLUTION

Fungal siderophore biosynthesis is partially localized in peroxisomes

(2013) Mario Gründlinger et al.   MOLECULAR MICROBIOLOGY

Hibernating Little Brown Myotis (Myotis lucifugus) Show Variable Immunological Responses to White-Nose Syndrome

(2013) Marianne S. Moore et al.   PLoS One

Prototype of an intertwined secondary-metabolite supercluster

(2013) P. Wiemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold

(2013) Zengyi Shao et al.   ACS Synthetic Biology

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

(2013) Erwin Berthier et al.   PLoS Pathogens

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

(2013) Thorsten Heinekamp et al.   Frontiers in Microbiology

Isotope-Assisted Screening for Iron-Containing Metabolites Reveals a High Degree of Diversity among Known and Unknown Siderophores Produced by Trichoderma spp.

(2012) Sylvia M. Lehner et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum

(2012) Jens Laurids Sørensen et al.   ENVIRONMENTAL MICROBIOLOGY

Production of fusarielins by Fusarium

(2012) Jens Laurids Sørensen et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Metabolites from Aspergillus fumigatus, an Endophytic Fungus Associated with Melia azedarach, and Their Antifungal, Antifeedant, and Toxic Activities

(2012) Xiao-Jun Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chemotypic and genotypic diversity in the ergot alkaloid pathway of Aspergillus fumigatus

(2012) S. L. Robinson et al.   MYCOLOGIA

Antibacterial activity of alkaloids produced by endophytic fungusAspergillussp. EJC08 isolated from medical plantBauhinia guianensis

(2012) Eduardo Antonio A. Pinheiro et al.   NATURAL PRODUCT RESEARCH

Trypacidin, a Spore-Borne Toxin from Aspergillus fumigatus, Is Cytotoxic to Lung Cells

(2012) Thierry Gauthier et al.   PLoS One

Accurate prediction of secondary metabolite gene clusters in filamentous fungi

(2012) M. R. Andersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathology in euthermic bats with white nose syndrome suggests a natural manifestation of immune reconstitution inflammatory syndrome

(2012) Carol U. Meteyer et al.   Virulence

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

(2011) Markus Schrettl et al.   CURRENT OPINION IN MICROBIOLOGY

Targeted Disruption of Nonribosomal Peptide Synthetasepes3Augments the Virulence of Aspergillus fumigatus

(2011) Karen A. O'Hanlon et al.   INFECTION AND IMMUNITY

Cloning and functional analysis of the second geranylgeranyl diphosphate synthase gene influencing helvolic acid biosynthesis in Metarhizium anisopliae

(2010) Suthitar Singkaravanit et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Intensity-based analysis of dual-color gene expression data as an alternative to ratio-based analysis to enhance reproducibility

(2010) Koen Bossers et al.   BMC GENOMICS

SMURF: Genomic mapping of fungal secondary metabolite clusters

(2010) Nora Khaldi et al.   FUNGAL GENETICS AND BIOLOGY

Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases

(2010) Takayuki Itoh et al.   Nature Chemistry

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

(2010) Markus Schrettl et al.   PLoS Pathogens

Identification of Two Aflatrem Biosynthesis Gene Loci in Aspergillus flavus and Metabolic Engineering of Penicillium paxilli To Elucidate Their Function

(2009) M. J. Nicholson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Pseurotin A and its analogues as inhibitors of immunoglobuline E production

(2009) Minoru Ishikawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Protostadienol Biosynthesis and Metabolism in the Pathogenic FungusAspergillus fumigatus

(2009) Silvia Lodeiro et al.   ORGANIC LETTERS

Fusarielin A as an Anti-angiogenic and Anti-proliferative Agent: Basic Biological Characterization

(2008) Haruka Fujimoto et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Gliotoxin Production inAspergillus fumigatusContributes to Host‐Specific Differences in Virulence

(2008) Sara Spikes et al.   JOURNAL OF INFECTIOUS DISEASES

SreA-mediated iron regulation in Aspergillus fumigatus

(2008) Markus Schrettl et al.   MOLECULAR MICROBIOLOGY

Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis

(2008) Andrew McDonagh et al.   PLoS Pathogens