Innate and adaptive T cells in influenza disease

Invariant natural killer T cells and mucosal-associated invariant T cells in multiple sclerosis

(2017) Elena Bianchini et al.   IMMUNOLOGY LETTERS

Influenza

(2017) Catharine Paules et al.   LANCET

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells

(2017) Angela Pizzolla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

(2017) Martin S. Davey et al.   Nature Communications

IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis

(2016) Eric Gracey et al.   ANNALS OF THE RHEUMATIC DISEASES

Mucosal-associated invariant T cells are reduced and functionally immature in the peripheral blood of primary Sjögren's syndrome patients

(2016) Jing J. Wang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Knowns and unknowns of influenza B viruses

(2016) Marios Koutsakos et al.   Future Microbiology

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation

(2016) Liyen Loh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for universal HLA-A*0201–restricted CD8+T-cell immunity against influenza viruses

(2016) Sophie A. Valkenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAIT cells are activated during human viral infections

(2016) Bonnie van Wilgenburg et al.   Nature Communications

Balancing Immune Protection and Immune Pathology by CD8+ T-Cell Responses to Influenza Infection

(2016) Susu Duan et al.   Frontiers in Immunology

α-Galactosylceramide protects swine against influenza infection when administered as a vaccine adjuvant

(2016) Bianca L. Artiaga et al.   Scientific Reports

ICOS+PD-1+CXCR3+ T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

(2016) Salah-Eddine Bentebibel et al.   Scientific Reports

Sterilizing immunity to influenza virus infection requires local antigen-specific T cell response in the lungs

(2016) Avijit Dutta et al.   Scientific Reports

Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study

(2015) Andrew C. Hayward et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Synthetic Influenza Virus Vaccine Induces a Cellular Immune Response That Correlates with Reduction in Symptomatology and Virus Shedding in a Randomized Phase Ib Live-Virus Challenge in Humans

(2015) Olga Pleguezuelos et al.   Clinical and Vaccine Immunology

Influenza B viruses: not to be discounted

(2015) Carolien E van de Sandt et al.   Future Microbiology

Influenza B virus-specific CD8+ T-lymphocytes strongly cross-react with viruses of the opposing influenza B lineage

(2015) Carolien E. van de Sandt et al.   JOURNAL OF GENERAL VIROLOGY

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites

(2015) Isaac G. Sakala et al.   JOURNAL OF IMMUNOLOGY

Human Influenza A Virus–Specific CD8+ T-Cell Response Is Long-lived

(2015) Carolien E. van de Sandt et al.   JOURNAL OF INFECTIOUS DISEASES

The burgeoning family of unconventional T cells

(2015) Dale I Godfrey et al.   NATURE IMMUNOLOGY

Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire

(2015) Tanya Dimova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterosubtypic immunity to H7N9 influenza virus in isogenic guinea pigs after infection with pandemic H1N1 virus

(2015) Lidewij C.M. Wiersma et al.   VACCINE

Establishment of functional influenza virus-specific CD8+ T cell memory pools after intramuscular immunization

(2015) Zhongfang Wang et al.   VACCINE

A novel peptide-based pan-influenza A vaccine: A double blind, randomised clinical trial of immunogenicity and safety

(2015) James N. Francis et al.   VACCINE

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells

(2015) Zhongfang Wang et al.   Nature Communications

Diverse Heterologous Primary Infections Radically Alter Immunodominance Hierarchies and Clinical Outcomes Following H7N9 Influenza Challenge in Mice

(2015) Susu Duan et al.   PLoS Pathogens

MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases

(2015) Lauren J. Howson et al.   Frontiers in Immunology

The Role of Mucosal Associated Invariant T Cells in Antimicrobial Immunity

(2015) Ruth J. Napier et al.   Frontiers in Immunology

Boosted Influenza-Specific T Cell Responses after H5N1 Pandemic Live Attenuated Influenza Virus Vaccination

(2015) YanChun Peng et al.   Frontiers in Immunology

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection

(2014) Brian J. Laidlaw et al.   IMMUNITY

Helping Themselves: Optimal Virus-Specific CD4 T Cell Responses Require Help via CD4 T Cell Licensing of Dendritic Cells

(2014) Matthew R. Olson et al.   JOURNAL OF IMMUNOLOGY

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities

(2014) S. Quinones-Parra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Vγ9Vδ2-T cells efficiently kill influenza virus-infected lung alveolar epithelial cells

(2013) Hong Li et al.   Cellular & Molecular Immunology

Human Cytotoxic T Lymphocytes Directed to Seasonal Influenza A Viruses Cross-React with the Newly Emerging H7N9 Virus

(2013) C. E. van de Sandt et al.   JOURNAL OF VIROLOGY

Cytokine-Dependent Induction of CD4+ T cells with Cytotoxic Potential during Influenza Virus Infection

(2013) L. Hua et al.   JOURNAL OF VIROLOGY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Examination of Influenza Specific T Cell Responses after Influenza Virus Challenge in Individuals Vaccinated with MVA-NP+M1 Vaccine

(2013) Timothy J. Powell et al.   PLoS One

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides

(2013) Sophie A. Valkenburg et al.   Nature Communications

Clearance of influenza virus infections by T cells: risk of collateral damage?

(2013) MLB Hillaire et al.   Current Opinion in Virology

Preliminary Assessment of the Efficacy of a T-Cell–Based Influenza Vaccine, MVA-NP+M1, in Humans

(2012) Patrick J. Lillie et al.   CLINICAL INFECTIOUS DISEASES

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

(2012) Shirley G.K. Seah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Safety and Immunogenicity of Multimeric-001—a Novel Universal Influenza Vaccine

(2012) Jacob Atsmon et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms

(2012) K. Kai McKinstry et al.   JOURNAL OF CLINICAL INVESTIGATION

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses

(2012) M. L. B. Hillaire et al.   JOURNAL OF GENERAL VIROLOGY

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Synthetic Influenza vaccine (FLU-v) stimulates cell mediated immunity in a double-blind, randomised, placebo-controlled Phase I trial

(2012) Olga Pleguezuelos et al.   VACCINE

Early Priming Minimizes the Age-Related Immune Compromise of CD8+ T Cell Diversity and Function

(2012) Sophie A. Valkenburg et al.   PLoS Pathogens

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Cytotoxic CD4 T Cells in Antiviral Immunity

(2011) Nikki B. Marshall et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a γδ T cell population in humanized mice

(2011) Wenwei Tu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Potential Role of Invariant NKT Cells in the Control of Pulmonary Inflammation and CD8+ T Cell Response during Acute Influenza A Virus H3N2 Pneumonia

(2011) C. Paget et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells and CD28 Costimulation Are Required To Sustain Virus-Specific CD8+ T Cell Responses during the Effector Phase In Vivo

(2011) D. V. Dolfi et al.   JOURNAL OF IMMUNOLOGY

Pivotal Advance: Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection

(2011) Wai Ling Kok et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Type 1 Responses of Human V 9V 2 T Cells to Influenza A Viruses

(2011) G. Qin et al.   JOURNAL OF VIROLOGY

A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human γδ T lymphocytes

(2010) Julie M. Jameson et al.   CELLULAR IMMUNOLOGY

Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA-NP+M1

(2010) T. K. Berthoud et al.   CLINICAL INFECTIOUS DISEASES

Cutting Edge: CD4 T Cells Generated from Encounter with Seasonal Influenza Viruses and Vaccines Have Broad Protein Specificity and Can Directly Recognize Naturally Generated Epitopes Derived from the Live Pandemic H1N1 Virus

(2010) K. A. Richards et al.   JOURNAL OF IMMUNOLOGY

Control systems and decision making for antibody production

(2010) Christopher C Goodnow et al.   NATURE IMMUNOLOGY

Cross-reactive CD8+T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

(2010) Stephanie Gras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An α-GalCer analogue with branched acyl chain enhances protective immune responses in a nasal influenza vaccine

(2010) Yoon-Sook Lee et al.   VACCINE

IFN-γ production downstream of NKT cell activation in mice infected with influenza virus enhances the cytolytic activities of both NK cells and viral antigen-specific CD8+ T cells

(2010) Hiroki Ishikawa et al.   VIROLOGY

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

(2010) Sophie A. Valkenburg et al.   PLoS Pathogens

NKT cell immune responses to viral infection

(2009) Marlowe S Tessmer et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Selected Toll-like Receptor Ligands and Viruses Promote Helper-Independent Cytotoxic T Cell Priming by Upregulating CD40L on Dendritic Cells

(2009) Susan Johnson et al.   IMMUNITY

Phosphoantigen‐Expanded Human γδ T Cells Display Potent Cytotoxicity against Monocyte‐Derived Macrophages Infected with Human and Avian Influenza Viruses

(2009) Gang Qin et al.   JOURNAL OF INFECTIOUS DISEASES

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity

(2009) C. Guillonneau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alpha-C-galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine

(2009) Sarah A. Kopecky-Bromberg et al.   VACCINE

Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection

(2008) Ling‐Pei Ho et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

(2008) Carmela De Santo et al.   JOURNAL OF CLINICAL INVESTIGATION

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF VIROLOGY

Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans

(2008) E. Assarsson et al.   JOURNAL OF VIROLOGY

Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population

(2008) J. M. Coquet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biology of influenza viruses

(2008) Nicole M. Bouvier et al.   VACCINE

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY