IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-05-15
DOI
10.3389/fimmu.2018.01037
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Drugmakers cling to dual IL-13/IL-4 blockbuster hopes
- (2018) Cormac Sheridan NATURE BIOTECHNOLOGY
- Estrogen Signaling Contributes to Sex Differences in Macrophage Polarization during Asthma
- (2017) Aleksander Keselman et al. JOURNAL OF IMMUNOLOGY
- IL-4/IL-13–mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury
- (2017) Ming-Zhi Zhang et al. KIDNEY INTERNATIONAL
- mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis
- (2017) R. W. Hallowell et al. Nature Communications
- IRS-2 rs1805097 polymorphism is associated with the decreased risk of colorectal cancer
- (2017) Jiefeng Yin et al. Oncotarget
- Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection
- (2017) Justin Komguep Nono et al. PLoS Neglected Tropical Diseases
- IRS proteins and diabetic complications
- (2016) Deborah P. Lavin et al. DIABETOLOGIA
- Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome
- (2016) Sarah M. McCormick et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2
- (2016) Kristi J. Warren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer
- (2016) Marc A. Becker et al. PLoS One
- The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation
- (2016) Preeta Dasgupta et al. Science Signaling
- IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617F-positive myeloproliferative neoplasms
- (2016) Paula de Melo Campos et al. Oncotarget
- The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation
- (2016) Preeta Dasgupta et al. Science Signaling
- IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death
- (2016) Sabine Rütti et al. Molecular Metabolism
- Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid
- (2015) Lucy H. Jones et al. INTERNATIONAL IMMUNOLOGY
- Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat
- (2014) Yifu Qiu et al. CELL
- Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis
- (2014) Rajesh R. Rao et al. CELL
- Myeloid-Specific Rictor Deletion Induces M1 Macrophage Polarization and Potentiates In Vivo Pro-Inflammatory Response to Lipopolysaccharide
- (2014) William T. Festuccia et al. PLoS One
- TSC1 controls macrophage polarization to prevent inflammatory disease
- (2014) Linnan Zhu et al. Nature Communications
- IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumors
- (2013) Holly A. Porter et al. CANCER LETTERS
- Rapamycin unbalances the polarization of human macrophages to M1
- (2013) Alessia Mercalli et al. IMMUNOLOGY
- Absence of the Common Gamma Chain (γc), a Critical Component of the Type I IL-4 Receptor, Increases the Severity of Allergic Lung Inflammation
- (2013) Preeta Dasgupta et al. PLoS One
- The TSC-mTOR pathway regulates macrophage polarization
- (2013) Vanessa Byles et al. Nature Communications
- Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation
- (2012) Andrew Q Ford et al. BMC IMMUNOLOGY
- Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
- (2012) K. D. Copps et al. DIABETOLOGIA
- Insulin receptor substrate 1 expression enhances the sensitivity of 32D cells to chemotherapy-induced cell death
- (2012) Holly A. Porter et al. EXPERIMENTAL CELL RESEARCH
- IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages
- (2012) Ashish Bhattacharjee et al. FREE RADICAL BIOLOGY AND MEDICINE
- The Extracellular and Transmembrane Domains of the γC and Interleukin (IL)-13 Receptor α1 Chains, Not Their Cytoplasmic Domains, Dictate the Nature of Signaling Responses to IL-4 and IL-13
- (2012) Nicola M. Heller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Contribution of Alternatively Activated Macrophages to Allergic Lung Inflammation: A Tale of Mice and Men
- (2012) Preeta Dasgupta et al. Journal of Innate Immunity
- Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines
- (2012) Ilkka S Junttila et al. Nature Chemical Biology
- IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro
- (2012) Nicola M. Heller et al. PLoS One
- Insulin Receptor Isoforms A and B as well as Insulin Receptor Substrates-1 and -2 Are Differentially Expressed in Prostate Cancer
- (2012) Martin Heni et al. PLoS One
- Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo
- (2012) P. C. Cook et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association betweenIRS-2G1057D polymorphism and risk of gastric cancer
- (2012) Xiao-Mei Zhao World Journal of Gastrointestinal Oncology
- Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells
- (2011) Oliver Stöhr et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Transfer of in vivo primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner
- (2011) Preeta Dasgupta et al. BMC IMMUNOLOGY
- Alternative activation of macrophages by IL-4 requires SHIP degradation
- (2011) Shelley B. Weisser et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- STAT6 Expression in Multiple Cell Types Mediates the Cooperative Development of Allergic Airway Disease
- (2011) S. P. Chapoval et al. JOURNAL OF IMMUNOLOGY
- IL-13 Receptor 1 Differentially Regulates Aeroallergen-Induced Lung Responses
- (2011) M. E. Rothenberg et al. JOURNAL OF IMMUNOLOGY
- Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity
- (2011) Hong-Erh Liang et al. NATURE IMMUNOLOGY
- Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
- (2011) D. Wu et al. SCIENCE
- Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis
- (2009) Bhumsoo Kim et al. APOPTOSIS
- Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System
- (2008) Sherry L. LaPorte et al. CELL
- Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
- (2008) Edy Y Kim et al. NATURE MEDICINE
- Distinct roles for IL-13 and IL-4 via IL-13 receptor 1 and the type II IL-4 receptor in asthma pathogenesis
- (2008) A. Munitz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages
- (2008) N. M. Heller et al. Science Signaling
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now