Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells

Allergen-specific immunotherapy induces regulatory T cells in an atopic dermatitis mouse model

(2018) J. U. Shin et al.   ALLERGY

Dichotomous function of IL-33 in health and disease: From biology to clinical implications

(2018) Harald Braun et al.   BIOCHEMICAL PHARMACOLOGY

New Treatments for Allergy: Advances in Peptide Immunotherapy

(2018) David Calzada et al.   CURRENT MEDICINAL CHEMISTRY

Induction of Interleukin-10 Producing Dendritic Cells As a Tool to Suppress Allergen-Specific T Helper 2 Responses

(2018) Stefan Schülke   Frontiers in Immunology

Mechanisms of immune regulation in allergic diseases: the role of regulatory T and B cells

(2017) Oscar Palomares et al.   IMMUNOLOGICAL REVIEWS

Stabilizing human regulatory T cells for tolerance inducing immunotherapy

(2017) Xuehui He et al.   Immunotherapy

Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers

(2017) Mohamed H. Shamji et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interleukin-35 on B cell and T cell induction and regulation

(2017) Ai Huang et al.   Journal of Inflammation-London

Heterogeneity and Stability in Foxp3+ Regulatory T Cells

(2017) Booki Min   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Allergy and Aging: An Old/New Emerging Health Issue

(2017) Massimo De Martinis et al.   Aging and Disease

Tregs: Where We Are and What Comes Next?

(2017) Hai Zhao et al.   Frontiers in Immunology

Regulatory T Cells in Allergy and Asthma

(2017) Elena Martín-Orozco et al.   Frontiers in Pediatrics

Role of Anti-inflammatory Cytokines IL-35 and IL-37 in Asthma

(2016) Daiju Hu   INFLAMMATION

Regulatory T cells in allergic diseases

(2016) Magali Noval Rivas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

USP21 prevents the generation of T-helper-1-like Treg cells

(2016) Yangyang Li et al.   Nature Communications

Applications and mechanisms of immunotherapy in allergic rhinitis and asthma

(2016) Jasper H. Kappen et al.   Therapeutic Advances in Respiratory Disease

MALT1 is an intrinsic regulator of regulatory T cells

(2015) A Brüstle et al.   CELL DEATH AND DIFFERENTIATION

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

(2015) Itay Raphael et al.   CYTOKINE

Current developments for improving efficacy of allergy vaccines

(2015) Alessandra Sandrini et al.   Expert Review of Vaccines

Phenotypic Complexity of the Human Regulatory T Cell Compartment Revealed by Mass Cytometry

(2015) Gavin M. Mason et al.   JOURNAL OF IMMUNOLOGY

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

(2015) H.-J. Kim et al.   SCIENCE

Modulation of immune responses by immunotherapy in allergic diseases

(2014) Ozlem Cavkaytar et al.   CURRENT OPINION IN PHARMACOLOGY

Regulatory T cells and immune regulation of allergic diseases: roles of IL-10 and TGF-β

(2014) O Palomares et al.   GENES AND IMMUNITY

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

Mechanisms of allergen-specific immunotherapy: Multiple suppressor factors at work in immune tolerance to allergens

(2014) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs

(2014) Cezmi A. Akdis et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: CD4 T Cell-Mast Cell Interactions Alter IgE Receptor Expression and Signaling

(2014) M. Kashyap et al.   JOURNAL OF IMMUNOLOGY

Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease

(2013) S. Dong et al.   BLOOD

The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

(2013) Zuojia Chen et al.   IMMUNITY

Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity

(2013) Jorg van Loosdregt et al.   IMMUNITY

Grass tablet sublingual immunotherapy downregulates the TH2 cytokine response followed by regulatory T-cell generation

(2013) Abel Suárez-Fueyo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of the E3 Deubiquitinase Ubiquitin-specific Peptidase 21 (USP21) as a Positive Regulator of the Transcription Factor GATA3

(2013) Jing Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Foxp3+ Inducible Regulatory T Cell Stability by SOCS2

(2013) C. A. Knosp et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of peripheral tolerance to allergens

(2012) O. U. Soyer et al.   ALLERGY

One hundred years of allergen immunotherapy European Academy of Allergy and Clinical Immunology celebration: review of unanswered questions

(2012) M. Calderón et al.   ALLERGY

Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

(2012) Angelina M. Bilate et al.   Annual Review of Immunology

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

(2012) T. Duhen et al.   BLOOD

Bcl6 Controls the Th2 Inflammatory Activity of Regulatory T Cells by Repressing Gata3 Function

(2012) D. V. Sawant et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-Cells: Diverse Phenotypes Integral to Immune Homeostasis and Suppression

(2012) Richard A. Peterson   TOXICOLOGIC PATHOLOGY

Mechanisms of Treg Suppression: Still a Long Way to Go

(2012) Dario A. A. Vignali   Frontiers in Immunology

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

The rs3761548 polymorphism of FOXP3 is a protective genetic factor against allergic rhinitis in the Hungarian female population

(2011) Eszter Fodor et al.   HUMAN IMMUNOLOGY

Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy

(2011) Erik Wambre et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice

(2011) Elizabeth A. Wohlfert et al.   JOURNAL OF CLINICAL INVESTIGATION

Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions

(2011) Tomoyuki Yamaguchi et al.   SEMINARS IN IMMUNOLOGY

Role of Treg in immune regulation of allergic diseases

(2010) Oscar Palomares et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites

(2010) Valentina Pacciani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetic association study of FOXP3 polymorphisms in allergic rhinitis in a Chinese population

(2009) Luo Zhang et al.   HUMAN IMMUNOLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Distinct regulation of IgE, IgG4 and IgA by T regulatory cells and toll-like receptors

(2008) F. Meiler et al.   ALLERGY

Heterogeneous response of nasal and lung fibroblasts to transforming growth factor-β1

(2008) M. Nonaka et al.   CLINICAL AND EXPERIMENTAL ALLERGY

CD4+CD25+ Regulatory T Cells Suppress Mast Cell Degranulation and Allergic Responses through OX40-OX40L Interaction

(2008) Giorgia Gri et al.   IMMUNITY

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Contextual Regulation of Inflammation: A Duet by Transforming Growth Factor-β and Interleukin-10

(2008) Ming O. Li et al.   IMMUNITY

In vivo switch to IL-10–secreting T regulatory cells in high dose allergen exposure

(2008) Flurina Meiler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans

(2008) Peter C. J. Janson et al.   PLoS One

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE