Mechanisms of peripheral tolerance to allergens

IL-10 Suppresses Mast Cell IgE Receptor Expression and Signaling In Vitro and In Vivo

(2014) S. Kennedy Norton et al.   JOURNAL OF IMMUNOLOGY

CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells

(2014) S. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Untangling asthma phenotypes and endotypes

(2012) I. Agache et al.   ALLERGY

TH17 and TH22 cells: A confusion of antimicrobial response with tissue inflammation versus protection

(2012) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inhibition of angiogenesis by IL-32: Possible role in asthma

(2012) Norbert Meyer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IgE class switching and cellular memory

(2012) Mübeccel Akdis et al.   NATURE IMMUNOLOGY

Therapies for allergic inflammation: refining strategies to induce tolerance

(2012) Cezmi A Akdis   NATURE MEDICINE

Mucosal dendritic cells in allergy and immunotherapy

(2011) N. Novak et al.   ALLERGY

Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

(2011) H. Hammad et al.   ALLERGY

Therapeutic induction of tolerance by IL-10-differentiated dendritic cells in a mouse model of house dust mite-asthma*

(2011) M. Lu et al.   ALLERGY

T-cell and antibody responses to phospholipase A2 from different species show distinct cross-reactivity patterns

(2011) B. A. Sin et al.   ALLERGY

Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy

(2011) M. H. Shamji et al.   ALLERGY

Persistent Activation of Dendritic Cells after Resolution of Allergic Airway Inflammation Breaks Tolerance to Inhaled Allergens in Mice

(2011) Leonie S. van Rijt et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CCL18 differentiates dendritic cells in tolerogenic cells able to prime regulatory T cells in healthy subjects

(2011) I. Azzaoui et al.   BLOOD

Fighting allergies beyond symptoms: The European Declaration on Immunotherapy

(2011) Cezmi Akdis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-33-activated dendritic cells are critical for allergic airway inflammation

(2011) Anne-Gaëlle Besnard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TIM polymorphisms—genetics and function

(2011) J Lee et al.   GENES AND IMMUNITY

TNF-like weak inducer of apoptosis (TWEAK) and TNF-α cooperate in the induction of keratinocyte apoptosis

(2011) Maya Zimmermann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory B-cell induction by helminths: Implications for allergic disease

(2011) Leonie Hussaarts et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation

(2011) Kentaro Takahashi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanisms of allergen-specific immunotherapy

(2011) Cezmi A. Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

(2011) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-35 production by inducible costimulator (ICOS)–positive regulatory T cells reverses established IL-17–dependent allergic airways disease

(2011) Gregory S. Whitehead et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance

(2011) Oscar Palomares et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Restricted Aeroallergen Access to Airway Mucosal Dendritic Cells In Vivo Limits Allergen-Specific CD4+ T Cell Proliferation during the Induction of Inhalation Tolerance

(2011) V. S. Fear et al.   JOURNAL OF IMMUNOLOGY

Thymic Stromal Lymphopoietin Is Produced by Dendritic Cells

(2011) M. Kashyap et al.   JOURNAL OF IMMUNOLOGY

Thymic Stromal Lymphopoietin Interferes with Airway Tolerance by Suppressing the Generation of Antigen-Specific Regulatory T Cells

(2011) L. Lei et al.   JOURNAL OF IMMUNOLOGY

Airway Inflammation and IgE Production Induced by Dust Mite Allergen-Specific Memory/Effector Th2 Cell Line Can Be Effectively Attenuated by IL-35

(2011) C.-H. Huang et al.   JOURNAL OF IMMUNOLOGY

STAT6-Dependent Regulation of Th9 Development

(2011) R. Goswami et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance

(2011) V. Chaturvedi et al.   JOURNAL OF IMMUNOLOGY

TSLP polymorphisms are associated with asthma in a sex-specific fashion

(2010) G. M. Hunninghake et al.   ALLERGY

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

(2010) S. Gregori et al.   BLOOD

Characterisation of allergen-specific responses of IL-10-producing regulatory B cells (Br1) in Cow Milk Allergy

(2010) Joonyong Noh et al.   CELLULAR IMMUNOLOGY

Increased Airway T Regulatory Cells in Asthmatic Subjects

(2010) Lucy J.C. Smyth et al.   CHEST

Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells

(2010) Valérie Staudt et al.   IMMUNITY

The T Cell Response to Major Grass Allergens Is Regulated and Includes IL-10 Production in Atopic but Not in Non-Atopic Subjects

(2010) A. Domdey et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Mechanisms of allergen-specific desensitization

(2010) Christina Uermösi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structure and function of immunoglobulins

(2010) Harry W. Schroeder et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model

(2010) Sylvie Amu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cellular and molecular basis for the regulation of inflammation by TGF- 

(2010) A. Yoshimura et al.   JOURNAL OF BIOCHEMISTRY

The Effector T Cell Response to Ryegrass Pollen Is Counterregulated by Simultaneous Induction of Regulatory T Cells

(2010) D. Mittag et al.   JOURNAL OF IMMUNOLOGY

RORC2 Is Involved in T Cell Polarization through Interaction with the FOXP3 Promoter

(2010) S. Burgler et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell co-transfected with FasL and allergen genes induces T cell tolerance and decreases airway inflammation in allergen induced murine model

(2010) Yan Wang et al.   MOLECULAR BIOLOGY REPORTS

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

Inhibition of allergic responses by CD40 gene silencing

(2009) M. Suzuki et al.   ALLERGY

Specific immunotherapy suppresses Th2 responses via modulating TIM1/TIM4 interaction on dendritic cells

(2009) C.-Q. Zhao et al.   ALLERGY

Impaired IL-10–dependent Induction of Tolerogenic Dendritic Cells by CD4+CD25hiCD127lo/−Natural Regulatory T Cells in Human Allergic Asthma

(2009) Khoa D. Nguyen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Histamine, histamine receptors and their role in immune pathology

(2009) M. Jutel et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Immunoglobulin G4: an odd antibody

(2009) R. C. Aalberse et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Immune tolerance in allergy

(2009) Mübeccel Akdis   CURRENT OPINION IN IMMUNOLOGY

Antigen-specific Treg regulate Th17-mediated lung neutrophilic inflammation, B-cell recruitment and polymeric IgA and IgM levels in the airways

(2009) Zeina Jaffar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein

(2009) Wayne G. Shreffler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Selective deregulation in chemokine signaling pathways of CD4+CD25hiCD127lo/− regulatory T cells in human allergic asthma

(2009) Khoa D. Nguyen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+inducible regulatory T cells

(2009) Sven Klunker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct regulation of IgE, IgG4 and IgA by T regulatory cells and toll-like receptors

(2008) F. Meiler et al.   ALLERGY

T-cell activation during exacerbations: a longitudinal study in refractory asthma

(2008) E. Mamessier et al.   ALLERGY

Attenuation of allergen-induced airway hyperresponsiveness is mediated by airway regulatory T cells

(2008) Jennifer T. Burchell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Peanut-specific B and T cell responses are correlated in peanut-allergic but not in non-allergic individuals

(2008) V. Turcanu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

(2008) Tomoki Ito et al.   IMMUNITY

CD4+CD25+ Regulatory T Cells Suppress Mast Cell Degranulation and Allergic Responses through OX40-OX40L Interaction

(2008) Giorgia Gri et al.   IMMUNITY

In vivo switch to IL-10–secreting T regulatory cells in high dose allergen exposure

(2008) Flurina Meiler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

(2008) Y. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA