RhoA/ROCK Signaling Pathway Mediates Shuanghuanglian Injection-Induced Pseudo-allergic Reactions

Reclassifying Anaphylaxis to Neuromuscular Blocking Agents Based on the Presumed Patho-Mechanism: IgE-Mediated, Pharmacological Adverse Reaction or “Innate Hypersensitivity”?

(2017) David Spoerl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endothelial Cell Junctional Adhesion Molecules

(2016) Natalia Reglero-Real et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Classification of Drug Hypersensitivity into Allergic, p-i, and Pseudo-Allergic Forms

(2016) Werner J. Pichler et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions

(2016) Jiayin Han et al.   Scientific Reports

Shuang-Huang-Lian Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice Involving Anti-Inflammatory and Antioxidative Activities

(2015) Lei Fang et al.   Evidence-based Complementary and Alternative Medicine

Study on the anaphylactoid of three phenolic acids in Honeysuckle

(2015) Fang Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Comprehensive identification of 125 multifarious constituents in Shuang–huang–lian powder injection by HPLC-DAD-ESI-IT-TOF-MS

(2015) Hongyang Sun et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

(2015) Constantinos M. Mikelis et al.   Nature Communications

Effects of high glucose on human umbilical vein endothelial cell permeability and myosin light chain phosphorylation

(2015) Xiao-Yan Zhao et al.   Diabetology & Metabolic Syndrome

International Consensus on drug allergy

(2014) P. Demoly et al.   ALLERGY

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

(2014) Benjamin D. McNeil et al.   NATURE

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

Chinese Medicine Injection Shuanghuanglian for Treatment of Acute Upper Respiratory Tract Infection: A Systematic Review of Randomized Controlled Trials

(2013) Hongwei Zhang et al.   Evidence-based Complementary and Alternative Medicine

Evaluation of the Potential Sensitization of Chlorogenic Acid: A Meta-Analysis

(2013) Mingbao Lin et al.   Evidence-based Complementary and Alternative Medicine

Chlorogenic acid alters the biological characteristics of basophil granulocytes by affecting the fluidity of the cell membrane and triggering pseudoallergic reactions

(2013) QIN LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

New method of screening allergenic components from Shuanghuanglian injection: With RBL-2H3/CMC model online HPLC/MS system

(2013) Shengli Han et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Shuang-Huang-Lian exerts anti-inflammatory and anti-oxidative activities in lipopolysaccharide-stimulated murine alveolar macrophages

(2013) Yuan Gao et al.   PHYTOMEDICINE

Nonallergic Drug Hypersensitivity Reactions

(2012) Kevin Farnam et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Structure–Activity Differences of Chlorogenic Acid and Its Isomers on Sensitization via Intravenous Exposure

(2012) Mingbao Lin et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Actin stress fibers - assembly, dynamics and biological roles

(2012) S. Tojkander et al.   JOURNAL OF CELL SCIENCE

Allergy, pseudo-allergy and non-allergy

(2011) Derek G. Waller   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Investigation of toxicological effects of Shuanghuanglian injection in Beagle dogs by metabonomic and traditional approaches

(2011) Guangyan Yan et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction

(2011) Jing Peng et al.   Journal of Neuroinflammation

Chemical correlation between Shuanghuanglian injection and its three raw herbs by LC fingerprint

(2011) Lijuan Liu et al.   JOURNAL OF SEPARATION SCIENCE

Vascular hyperpermeability in response to inflammatory mustard oil is mediated by Rho kinase in mice systemically exposed to arsenic

(2011) Shih-Chieh Chen et al.   MICROVASCULAR RESEARCH

Apelin-13 passes through the ADMA-damaged endothelial barrier and acts on vascular smooth muscle cells

(2011) Li-Yan Wang et al.   PEPTIDES

Mast cell degranulation induced by chlorogenic acid

(2010) Fang-hua Huang et al.   ACTA PHARMACOLOGICA SINICA

The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications

(2009) Elisabetta Dejana et al.   DEVELOPMENTAL CELL

Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation

(2009) P. Y. Mong et al.   JOURNAL OF IMMUNOLOGY

Deciphering the functional role of endothelial junctions by using in vivo models

(2008) Daniel Nyqvist et al.   EMBO REPORTS

Endothelial cell junctions and the regulation of vascular permeability and leukocyte transmigration

(2008) A. AGHAJANIAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

(2007) Yann Wallez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton

(2007) Andrea Hartsock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES