Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
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Title
Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
Authors
Keywords
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Journal
Cancer Medicine
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-06-21
DOI
10.1002/cam4.1594
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Note: Only part of the references are listed.- AMPK: Sensing Glucose as well as Cellular Energy Status
- (2018) Sheng-Cai Lin et al. Cell Metabolism
- Glucose starvation increases V-ATPase assembly and activity in mammalian cells through AMP kinase and phosphatidylinositide 3-kinase/Akt signaling
- (2018) Christina M. McGuire et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The curious case of vacuolar ATPase: regulation of signaling pathways
- (2018) Sahithi Pamarthy et al. Molecular Cancer
- Mammary epithelium-specific inactivation of V-ATPase reduces stiffness of extracellular matrix and enhances metastasis of breast cancer
- (2017) Gajendra K. Katara et al. Molecular Oncology
- Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
- (2017) Chen-Song Zhang et al. NATURE
- Osteoclast proton pump regulator Atp6v1c1 enhances breast cancer growth by activating the mTORC1 pathway and bone metastasis by increasing V-ATPase activity
- (2017) Matthew McConnell et al. Oncotarget
- Proton Pump Inhibition Enhances the Cytotoxicity of Paclitaxel in Cervical Cancer
- (2017) Taejong Song et al. Cancer Research and Treatment
- F-actin reorganization by V-ATPase inhibition in prostate cancer
- (2017) Yamhilette Licon-Munoz et al. Biology Open
- Drug Repositioning of Proton Pump Inhibitors for Enhanced Efficacy and Safety of Cancer Chemotherapy
- (2017) Kenji Ikemura et al. Frontiers in Pharmacology
- Regulation of V-ATPase assembly and function of V-ATPases in tumor cell invasiveness
- (2016) Christina McGuire et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- COSMIC: somatic cancer genetics at high-resolution
- (2016) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- The Function of V-ATPases in Cancer
- (2016) Laura Stransky et al. PHYSIOLOGICAL REVIEWS
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling
- (2016) Sahithi Pamarthy et al. Cell Death & Disease
- Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy
- (2016) Ying Gao et al. Cell Death & Disease
- Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma
- (2016) Sung Wook Son et al. Oncotarget
- The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer
- (2016) Kristina Cotter et al. Oncotarget
- Oncogenic regulation of tumor metabolic reprogramming
- (2016) Míriam Tarrado-Castellarnau et al. Oncotarget
- V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy
- (2016) Karin Bartel et al. Oncotarget
- Proton Pump Inhibitors Display Antitumor Effects in Barrett's Adenocarcinoma Cells
- (2016) Eduardo Chueca et al. Frontiers in Pharmacology
- Role of vacuolar-type proton ATPase in signal transduction
- (2015) Ge-Hong Sun-Wada et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer
- (2015) L. S. Schneider et al. CANCER RESEARCH
- Expression and role of V1A subunit of V-ATPases in gastric cancer cells
- (2015) Pengfei Liu et al. International Journal of Clinical Oncology
- Amino Acid Availability Modulates Vacuolar H+-ATPase Assembly
- (2015) Laura A. Stransky et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
- (2015) Jessica Okosun et al. NATURE GENETICS
- Inhibition of vacuolar ATPase subunit in tumor cells delays tumor growth by decreasing the essential macrophage population in the tumor microenvironment
- (2015) G K Katara et al. ONCOGENE
- TM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cells
- (2015) F Lozupone et al. ONCOGENE
- Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation
- (2015) Michael R. Green et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification
- (2015) Caroline Mauvezin et al. Nature Communications
- The Vacuolar ATPase a2-subunit regulates Notch signaling in triple-negative breast cancer cells
- (2015) Sahithi Pamarthy et al. Oncotarget
- Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer
- (2015) Arpita Kulshrestha et al. Oncotarget
- Inhibition of the vacuolar ATPase induces Bnip3-dependent death of cancer cells and a reduction in tumor burden and metastasis
- (2015) Regina M. Graham et al. Oncotarget
- The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism
- (2014) Chen-Song Zhang et al. Cell Metabolism
- Yeast Phosphofructokinase-1 Subunit Pfk2p Is Necessary for pH Homeostasis and Glucose-dependent Vacuolar ATPase Reassembly
- (2014) Chun-Yuan Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activity of Plasma Membrane V-ATPases Is Critical for the Invasion of MDA-MB231 Breast Cancer Cells
- (2014) Kristina Cotter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells
- (2014) C. M. Schempp et al. MOLECULAR CANCER THERAPEUTICS
- Atp6v1c1 May Regulate Filament Actin Arrangement in Breast Cancer Cells
- (2014) Shengmei Feng et al. PLoS One
- V-ATPase is a candidate therapeutic target for Ewing sarcoma
- (2013) Sofia Avnet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer
- (2013) Qiang Lu et al. Diagnostic Pathology
- Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer
- (2013) An Hendrix et al. INTERNATIONAL JOURNAL OF CANCER
- V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activationin vivo
- (2013) Rebekka Kubisch et al. INTERNATIONAL JOURNAL OF CANCER
- The Function of Vacuolar ATPase (V-ATPase) a Subunit Isoforms in Invasiveness of MCF10a and MCF10CA1a Human Breast Cancer Cells
- (2013) Joseph Capecci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell
- (2013) Xiaoyan Xu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- V-ATPase inhibition overcomes trastuzumab resistance in breast cancer
- (2013) Karin von Schwarzenberg et al. Molecular Oncology
- Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
- (2013) G K Katara et al. ONCOGENE
- HRG-1 enhances cancer cell invasive potential and couples glucose metabolism to cytosolic/extracellular pH gradient regulation by the vacuolar-H+ ATPase
- (2013) F M Fogarty et al. ONCOGENE
- The V-ATPase-Inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1
- (2012) R. M. Wiedmann et al. CANCER RESEARCH
- Expression and functional role of vacuolar H+-ATPase in human hepatocellular carcinoma
- (2012) J. Xu et al. CARCINOGENESIS
- Novel Insights into V-ATPase Functioning: Distinct Roles for its Accessory Subunits ATP6AP1/Ac45 and ATP6AP2/(pro) Renin Receptor
- (2012) Eric J.R. Jansen et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- ABCG2/V-ATPase was associated with the drug resistance and tumor metastasis of esophageal squamous cancer cells
- (2012) Lijun Huang et al. Diagnostic Pathology
- The renal v-ATPase a4 subunit is expressed in specific subtypes of human gliomas
- (2012) Vincent Gleize et al. GLIA
- Inhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion
- (2012) Vera Michel et al. INTERNATIONAL JOURNAL OF CANCER
- Epidermal Growth Factor-induced Vacuolar (H+)-ATPase Assembly
- (2012) Yanqing Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition
- (2012) Karin von Schwarzenberg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump
- (2012) S Fan et al. ONCOGENE
- V-ATPase engagement in autophagic processes
- (2011) Dalibor Mijaljica et al. Autophagy
- Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa
- (2011) A García-García et al. BIOTECHNIC & HISTOCHEMISTRY
- The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
- (2011) Chuhan Chung et al. LABORATORY INVESTIGATION
- The a3 Isoform Vacuolar Type H+-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells
- (2011) T. Nishisho et al. MOLECULAR CANCER RESEARCH
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
- (2011) R. Zoncu et al. SCIENCE
- Regulation and Isoform Function of the V-ATPases
- (2010) Masashi Toei et al. BIOCHEMISTRY
- Measurement of ATP6V1C1 expression in brush cytology samples as a diagnostic and prognostic marker in oral squamous cell carcinoma
- (2010) Mario Pérez-Sayáns et al. CANCER BIOLOGY & THERAPY
- The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor
- (2010) T. Vaccari et al. DEVELOPMENT
- PKA Regulates Vacuolar H+-ATPase Localization and Activity via Direct Phosphorylation of the A Subunit in Kidney Cells
- (2010) Rodrigo Alzamora et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Iron Uptake Is Responsible for Differential Sensitivity to V-ATPase Inhibitors in Several Cancer Cell Lines
- (2010) Sarah Straud et al. PLoS One
- Requirement of Prorenin Receptor and Vacuolar H+-ATPase-Mediated Acidification for Wnt Signaling
- (2010) C.-M. Cruciat et al. SCIENCE
- AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells
- (2009) Kenneth R. Hallows et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells
- (2009) Ya Chun Wu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells
- (2009) Haiyan You et al. CANCER LETTERS
- Vacuolar H+-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway
- (2009) Yukiko Sasazawa et al. CANCER SCIENCE
- The Vacuolar Proton Pump, V-ATPase, Is Required for Notch Signaling and Endosomal Trafficking in Drosophila
- (2009) Yan Yan et al. DEVELOPMENTAL CELL
- pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
- (2009) Angelo De Milito et al. INTERNATIONAL JOURNAL OF CANCER
- Function of a Subunit Isoforms of the V-ATPase in pH Homeostasis andin VitroInvasion of MDA-MB231 Human Breast Cancer Cells
- (2009) Ayana Hinton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibitors of V-ATPases: old and new players
- (2009) M. Huss et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Evaluating the potential of Vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamide
- (2008) Sylvain Lebreton et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma
- (2008) Toshiya Morimura et al. PEDIATRIC SURGERY INTERNATIONAL
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